Entry euk:PPR64_ARATH

ID   PPR64_ARATH             Reviewed;        1006 AA.
AC   Q9SA76;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   12-APR-2017, entry version 100.
DE   RecName: Full=Pentatricopeptide repeat-containing protein At1g30610, chloroplastic;
DE   AltName: Full=Protein EMBRYO DEFECTIVE 2279;
DE   Flags: Precursor;
GN   Name=EMB2279; OrderedLocusNames=At1g30610; ORFNames=T5I8.6;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S.,
RA   White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y.,
RA   Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W.,
RA   Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K.,
RA   Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y.,
RA   Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L.,
RA   Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E.,
RA   Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B.,
RA   Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P.,
RA   Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A.,
RA   Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I.,
RA   Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D.,
RA   Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M.,
RA   Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M.,
RA   Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Portal (Araport);
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   GENE FAMILY.
RX   PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA   Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA   Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A.,
RA   Le Ret M., Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P.,
RA   Szurek B., Taconnat L., Small I.;
RT   "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT   reveals their essential role in organelle biogenesis.";
RL   Plant Cell 16:2089-2103(2004).
RN   [4]
RP   FUNCTION.
RX   PubMed=15647901; DOI=10.1007/s00425-004-1452-x;
RA   Cushing D.A., Forsthoefel N.R., Gestaut D.R., Vernon D.M.;
RT   "Arabidopsis emb175 and other ppr knockout mutants reveal essential
RT   roles for pentatricopeptide repeat (PPR) proteins in plant
RT   embryogenesis.";
RL   Planta 221:424-436(2005).
CC   -!- FUNCTION: May play a role in embryogenesis.
CC       {ECO:0000269|PubMed:15647901}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=1;
CC         Comment=A number of isoforms are produced. According to EST
CC         sequences.;
CC       Name=1;
CC         IsoId=Q9SA76-1; Sequence=Displayed;
CC   -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=Arabidopsis PPR Protein Database;
CC       URL="http://www.plantenergy.uwa.edu.au/applications/ppr/ppr.php";
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DR   EMBL; AC007060; AAD25748.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE31249.1; -; Genomic_DNA.
DR   PIR; D86431; D86431.
DR   RefSeq; NP_174349.1; NM_102798.2. [Q9SA76-1]
DR   UniGene; At.51842; -.
DR   ProteinModelPortal; Q9SA76; -.
DR   STRING; 3702.AT1G30610.1; -.
DR   iPTMnet; Q9SA76; -.
DR   PaxDb; Q9SA76; -.
DR   PRIDE; Q9SA76; -.
DR   EnsemblPlants; AT1G30610.1; AT1G30610.1; AT1G30610. [Q9SA76-1]
DR   GeneID; 839941; -.
DR   Gramene; AT1G30610.1; AT1G30610.1; AT1G30610.
DR   KEGG; ath:AT1G30610; -.
DR   Araport; AT1G30610; -.
DR   TAIR; locus:2204629; AT1G30610.
DR   eggNOG; KOG4197; Eukaryota.
DR   eggNOG; ENOG410Z7Z7; LUCA.
DR   HOGENOM; HOG000082730; -.
DR   InParanoid; Q9SA76; -.
DR   OMA; SAGRCNE; -.
DR   OrthoDB; EOG093603PT; -.
DR   PhylomeDB; Q9SA76; -.
DR   PRO; PR:Q9SA76; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9SA76; baseline and differential.
DR   Genevisible; Q9SA76; AT.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0004519; F:endonuclease activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR   GO; GO:0009451; P:RNA modification; IBA:GO_Central.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR011990; TPR-like_helical_dom.
DR   Pfam; PF01535; PPR; 2.
DR   Pfam; PF13041; PPR_2; 1.
DR   Pfam; PF13812; PPR_3; 1.
DR   SUPFAM; SSF48452; SSF48452; 2.
DR   TIGRFAMs; TIGR00756; PPR; 4.
DR   PROSITE; PS51375; PPR; 10.
PE   3: Inferred from homology;
KW   Alternative splicing; Chloroplast; Complete proteome; Plastid;
KW   Reference proteome; Repeat; Transit peptide.
FT   TRANSIT       1     40       Chloroplast. {ECO:0000255}.
FT   CHAIN        41   1006       Pentatricopeptide repeat-containing
FT                                protein At1g30610, chloroplastic.
FT                                /FTId=PRO_0000342805.
FT   REPEAT      468    502       PPR 1.
FT   REPEAT      506    536       PPR 2.
FT   REPEAT      542    572       PPR 3.
FT   REPEAT      592    626       PPR 4.
FT   REPEAT      627    657       PPR 5.
FT   REPEAT      661    695       PPR 6.
FT   REPEAT      759    789       PPR 7.
FT   REPEAT      793    827       PPR 8.
FT   REPEAT      840    874       PPR 9.
FT   REPEAT      875    909       PPR 10.
FT   COMPBIAS    106    111       Poly-Gly.
FT   COMPBIAS    399    403       Poly-Asp.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT       591    635       ipfam:PPR_2 [T]
FT   MYHIT       592    626       iprf:PPR [T]
FT   MYHIT       661    695       iprf:PPR [T]
FT   MYHIT       875    909       iprf:PPR [T]
FT   MYHIT       506    536       iprf:PPR [T]
FT   MYHIT       509    534       ipfam:PPR [T]
FT   MYHIT       793    827       iprf:PPR [T]
FT   MYHIT       665    693       ipfam:PPR [T]
FT   MYHIT       627    657       iprf:PPR [T]
FT   MYHIT       840    874       iprf:PPR [T]
FT   MYHIT       758    804       ipfam:PPR_3 [T]
FT   MYHIT       542    572       iprf:PPR [T]
FT   MYHIT       468    502       iprf:PPR [T]
FT   MYHIT       759    789       iprf:PPR [T]
SQ   SEQUENCE   1006 AA;  116095 MW;  339BE7E79444EF71 CRC64;
     MAVTISTNAF VNASLLDESR NSFWRPLFHQ PYYNCRRVVR LNSRKLNSKV MFCLNLNTKE
     VGLQKPGDKG FEFKPSFDQY LQIMESVKTA RKKKKFDRLK VEEDDGGGGN GDSVYEVKDM
     KIKSGELKDE TFRKRYSRQE IVSDKRNERV FKRNGEIENH RVATDLKWSK SGESSVALKL
     SKSGESSVTV PEDESFRKRY SKQEYHRSSD TSRGIERGSR GDELDLVVEE RRVQRIAKDA
     RWSKSRESSV AVKWSNSGES SVTMPKDESF RRRYSKQEHH RSSDTSRGIA RGSKGDELEL
     VVEERRVQRI AKDVRWSKSD ESLVPVSEDE SFRRGNPKQE MVRYQRVSDT SRGIERGSKG
     DGLDLLAEER RIERLANERH EIRSSKLSGT RRIGAKRNDD DDDSLFAMET PAFRFSDESS
     DIVDKPATSR VEMEDRIEKL AKVLNGADIN MPEWQFSKAI RSAKIRYTDY TVMRLIHFLG
     KLGNWRRVLQ VIEWLQRQDR YKSNKIRIIY TTALNVLGKS RRPVEALNVF HAMLLQISSY
     PDMVAYRSIA VTLGQAGHIK ELFYVIDTMR SPPKKKFKPT TLEKWDPRLE PDVVVYNAVL
     NACVQRKQWE GAFWVLQQLK QRGQKPSPVT YGLIMEVMLA CEKYNLVHEF FRKMQKSSIP
     NALAYRVLVN TLWKEGKSDE AVHTVEDMES RGIVGSAALY YDLARCLCSA GRCNEGLNMV
     NFVNPVVLKL IENLIYKADL VHTIQFQLKK ICRVANKPLV VTYTGLIQAC VDSGNIKNAA
     YIFDQMKKVC SPNLVTCNIM LKAYLQGGLF EEARELFQKM SEDGNHIKNS SDFESRVLPD
     TYTFNTMLDT CAEQEKWDDF GYAYREMLRH GYHFNAKRHL RMVLEASRAG KEEVMEATWE
     HMRRSNRIPP SPLIKERFFR KLEKGDHISA ISSLADLNGK IEETELRAFS TSAWSRVLSR
     FEQDSVLRLM DDVNRRLGSR SESSDSVLGN LLSSCKDYLK TRTHNL
//