Legends: 1, N-linked (GlcNAc...) asparagine. {ECO:0000255}; 2, TOPO_DOM Extracellular. {ECO:0000255}; 3, TRANSMEM Helical; Name=1. {ECO:0000255}; 4, TOPO_DOM Cytoplasmic. {ECO:0000255}; 5, TRANSMEM Helical; Name=2. {ECO:0000255}; 6, TRANSMEM Helical; Name=3. {ECO:0000255}; 7, TRANSMEM Helical; Name=4. {ECO:0000255}; 8, TRANSMEM Helical; Name=5. {ECO:0000255}; 9, TRANSMEM Helical; Name=6. {ECO:0000255}; 10, TRANSMEM Helical; Name=7. {ECO:0000255}; 11, ipat:G_PROTEIN_RECEP_F1_1 [T].
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ID OL494_MOUSE Reviewed; 314 AA.
AC Q8VG07;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 10-MAY-2017, entry version 110.
DE RecName: Full=Olfactory receptor 494;
DE AltName: Full=Olfactory receptor 204-10;
GN Name=Olfr494; Synonyms=Mor204-10;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [3]
RP ERRATUM.
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RL Hum. Mol. Genet. 11:1683-1683(2002).
CC -!- FUNCTION: Potential odorant receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY073358; AAL61021.1; -; Genomic_DNA.
DR EMBL; AY317602; AAP70997.1; -; Genomic_DNA.
DR CCDS; CCDS21713.1; -.
DR RefSeq; NP_666948.1; NM_146737.1.
DR UniGene; Mm.377662; -.
DR ProteinModelPortal; Q8VG07; -.
DR STRING; 10090.ENSMUSP00000072810; -.
DR PaxDb; Q8VG07; -.
DR PRIDE; Q8VG07; -.
DR Ensembl; ENSMUST00000209743; ENSMUSP00000148063; ENSMUSG00000109631.
DR Ensembl; ENSMUST00000210291; ENSMUSP00000147830; ENSMUSG00000109631.
DR GeneID; 258732; -.
DR KEGG; mmu:258732; -.
DR UCSC; uc009jci.1; mouse.
DR CTD; 258732; -.
DR MGI; MGI:3030328; Olfr494.
DR GeneTree; ENSGT00550000074423; -.
DR HOGENOM; HOG000041364; -.
DR HOVERGEN; HBG017625; -.
DR InParanoid; Q8VG07; -.
DR KO; K04257; -.
DR OMA; TISYIAC; -.
DR OrthoDB; EOG091G0CLJ; -.
DR PhylomeDB; Q8VG07; -.
DR TreeFam; TF338848; -.
DR Reactome; R-MMU-381753; Olfactory Signaling Pathway.
DR PRO; PR:Q8VG07; -.
DR Proteomes; UP000000589; Chromosome 7.
DR CleanEx; MM_OLFR494; -.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Complete proteome; Disulfide bond;
KW G-protein coupled receptor; Glycoprotein; Membrane; Olfaction;
KW Receptor; Reference proteome; Sensory transduction; Transducer;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1 314 Olfactory receptor 494.
FT /FTId=PRO_0000150849.
FT TOPO_DOM 1 28 Extracellular. {ECO:0000255}.
FT TRANSMEM 29 49 Helical; Name=1. {ECO:0000255}.
FT TOPO_DOM 50 57 Cytoplasmic. {ECO:0000255}.
FT TRANSMEM 58 78 Helical; Name=2. {ECO:0000255}.
FT TOPO_DOM 79 102 Extracellular. {ECO:0000255}.
FT TRANSMEM 103 123 Helical; Name=3. {ECO:0000255}.
FT TOPO_DOM 124 136 Cytoplasmic. {ECO:0000255}.
FT TRANSMEM 137 157 Helical; Name=4. {ECO:0000255}.
FT TOPO_DOM 158 199 Extracellular. {ECO:0000255}.
FT TRANSMEM 200 220 Helical; Name=5. {ECO:0000255}.
FT TOPO_DOM 221 240 Cytoplasmic. {ECO:0000255}.
FT TRANSMEM 241 261 Helical; Name=6. {ECO:0000255}.
FT TOPO_DOM 262 274 Extracellular. {ECO:0000255}.
FT TRANSMEM 275 295 Helical; Name=7. {ECO:0000255}.
FT TOPO_DOM 296 314 Cytoplasmic. {ECO:0000255}.
FT CARBOHYD 8 8 N-linked (GlcNAc...) asparagine.
FT {ECO:0000255}.
FT DISULFID 100 192 {ECO:0000255|PROSITE-ProRule:PRU00521}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 44 293 iprf:G_PROTEIN_RECEP_F1_2 [T]
FT MYHIT 113 129 ipat:G_PROTEIN_RECEP_F1_1 [T]
SQ SEQUENCE 314 AA; 34658 MW; 71BC08397C5884BD CRC64;
MAFLQDGNHT AVTEFILLGL TDGPILRVIL FTIILCIYLV TVSGNLSTIL LIRVSSQLHH
PMYFFLSHLA SVDMGLSSSV TPNMLVNFLV KQNTISYIAC SIQFGLAAFF GTVECFLLAA
MAYDRFVAIC NPLLYSTKIS TESCIQLVVG SYIGGFLNAS SFILSFFSFI FCGPNRINHF
YCDLAPLVEL SCSDVSVSVV VTSFSAGSVT VITVFVIAVS YSYILITILK MHSTEGRHKA
FSTCTSHLTA VTLYYGTITF IYVMPKSSYS TDQNKVVSVF YMVVIPMLNP LIYSLRNNEI
KGAIKRQLGK KMFC
//
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