ID O17013_CAEEL Unreviewed; 399 AA.
AC O17013;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 04-APR-2006, sequence version 2.
DT 10-MAY-2017, entry version 137.
DE SubName: Full=Nuclear Hormone Receptor family {ECO:0000313|EMBL:CCD71087.1};
GN Name=nhr-270 {ECO:0000313|EMBL:CCD71087.1,
GN ECO:0000313|WormBase:R13D11.8a};
GN ORFNames=CELE_R13D11.8 {ECO:0000313|EMBL:CCD71087.1},
GN R13D11.8 {ECO:0000313|WormBase:R13D11.8a};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD71087.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD71087.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD71087.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for
RT investigating biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
CC ProRule:PRU00407, ECO:0000256|SAAS:SAAS00817906}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|SAAS:SAAS00817792}.
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DR EMBL; BX284605; CCD71087.1; -; Genomic_DNA.
DR PIR; G88941; G88941.
DR RefSeq; NP_503328.2; NM_070927.5.
DR UniGene; Cel.27492; -.
DR ProteinModelPortal; O17013; -.
DR IntAct; O17013; 1.
DR PaxDb; O17013; -.
DR EnsemblMetazoa; R13D11.8; R13D11.8; WBGene00020062.
DR EnsemblMetazoa; R13D11.8a; R13D11.8a; WBGene00020062.
DR GeneID; 187867; -.
DR KEGG; cel:CELE_R13D11.8; -.
DR UCSC; R13D11.8; c. elegans.
DR CTD; 187867; -.
DR WormBase; R13D11.8a; CE39955; WBGene00020062; nhr-270.
DR eggNOG; KOG3575; Eukaryota.
DR eggNOG; ENOG410XRZC; LUCA.
DR GeneTree; ENSGT00530000064753; -.
DR HOGENOM; HOG000017606; -.
DR InParanoid; O17013; -.
DR OMA; CGDQVKS; -.
DR OrthoDB; EOG091G0GHB; -.
DR PhylomeDB; O17013; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00020062; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF48508; SSF48508; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW Complete proteome {ECO:0000313|Proteomes:UP000001940};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00517091};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00517125};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00134727};
KW Receptor {ECO:0000313|EMBL:CCD71087.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transcription {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00134739};
KW Transcription regulation {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00134739};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00517125};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00517125}.
FT DOMAIN 67 142 Nuclear receptor DNA-binding.
FT {ECO:0000259|PROSITE:PS51030}.
FT DNA_BIND 67 142 Nuclear receptor. {ECO:0000256|PROSITE-
FT ProRule:PRU00407}.
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CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 195 371 ismart:HOLI [T]
FT MYHIT 69 136 ipfam:zf-C4 [T]
FT MYHIT 67 142 iprf:NUCLEAR_REC_DBD_2 [T]
FT MYHIT 176 384 ipfam:Hormone_recep [T]
FT MYHIT 67 138 ismart:ZnF_C4 [T]
SQ SEQUENCE 399 AA; 45079 MW; 9CC2D99FDAB4176A CRC64;
MPYEFAGGPY RPLCPLSKIS RRWNLNSRGG AIVPSSTSVH SLGHSISMLA VMSPSTSKAP
NLIAILTERC AVCGDQVKSD RLGCPACLGC ILFFRRSVLK NASYKCGRKG ACPVVSEFRS
TCRHCRFKKC FDVGMKASAV NTCIANPSPP PYVDVPKDLL GPCVILQTRQ IEEHKEQSVK
HVRRASASDV NKMLMWSFND AVEWASDYEP FQLLPNELQK CVISEFGVAF FLIDQGFKSA
RESKRGFWMF QNGTFLHFDY FHGLANIDDT ADREKTKHHC EFVQYLEVTI KQQFQLLQID
EFELAAIKTL LLLSCSYPKP EIFAEFKGTM QKLKNKCFAE LMSYLTVKLP ATHAERFGKL
ILVMGEIRAA VKVLYNHTKV SDLFDPSKFN MFVRSFLLT
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