ID O16390_CAEEL Unreviewed; 359 AA.
AC O16390;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 3.
DT 10-MAY-2017, entry version 143.
DE SubName: Full=Nuclear Hormone Receptor family {ECO:0000313|EMBL:CCD64872.2};
GN Name=nhr-159 {ECO:0000313|EMBL:CCD64872.2,
GN ECO:0000313|WormBase:C17E7.7a};
GN ORFNames=C17E7.7 {ECO:0000313|WormBase:C17E7.7a},
GN CELE_C17E7.7 {ECO:0000313|EMBL:CCD64872.2};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD64872.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD64872.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD64872.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for
RT investigating biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
CC ProRule:PRU00407, ECO:0000256|SAAS:SAAS00817906}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|SAAS:SAAS00817792}.
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DR EMBL; BX284605; CCD64872.2; -; Genomic_DNA.
DR RefSeq; NP_504069.2; NM_071668.3.
DR UniGene; Cel.36718; -.
DR ProteinModelPortal; O16390; -.
DR PaxDb; O16390; -.
DR EnsemblMetazoa; C17E7.7; C17E7.7; WBGene00015902.
DR GeneID; 182732; -.
DR KEGG; cel:CELE_C17E7.7; -.
DR UCSC; C17E7.7; c. elegans.
DR CTD; 182732; -.
DR WormBase; C17E7.7a; CE46871; WBGene00015902; nhr-159.
DR eggNOG; ENOG410KATF; Eukaryota.
DR eggNOG; ENOG4110HYK; LUCA.
DR GeneTree; ENSGT00530000064378; -.
DR HOGENOM; HOG000015902; -.
DR InParanoid; O16390; -.
DR OMA; FFALYTT; -.
DR OrthoDB; EOG091G0JCB; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00015902; -.
DR ExpressionAtlas; O16390; baseline.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0043401; P:steroid hormone mediated signaling pathway; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF48508; SSF48508; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW Complete proteome {ECO:0000313|Proteomes:UP000001940};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00517091};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00517125};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00134727};
KW Receptor {ECO:0000313|EMBL:CCD64872.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transcription {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00134739};
KW Transcription regulation {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00134739};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00517125};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00407,
KW ECO:0000256|SAAS:SAAS00517125}.
FT DOMAIN 16 95 Nuclear receptor DNA-binding.
FT {ECO:0000259|PROSITE:PS51030}.
FT DNA_BIND 16 95 Nuclear receptor. {ECO:0000256|PROSITE-
FT ProRule:PRU00407}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 18 89 ipfam:zf-C4 [T]
FT MYHIT 16 91 ismart:ZnF_C4 [T]
FT MYHIT 16 95 iprf:NUCLEAR_REC_DBD_2 [T]
FT MYHIT 162 332 ismart:HOLI [T]
FT MYHIT 163 331 ipfam:Hormone_recep [T]
SQ SEQUENCE 359 AA; 41545 MW; FC6D64F1921A30FF CRC64;
MSSSPPSLSE YSFIDPRKCL VCYRPAYCNN YGVLTCDACK MFFRRVVTEK LEYTCKCSNN
CFEGFSEDST IYPKCKSCRY QECLKFGMNY AFRKQKRLLE IRNKKDDELD AIIDGLRYLD
NHRRETLRTK FTISNPTLQE MVEKKGLETY VKTPKEQLRP QDWSFFALYT TVEFLSNMPF
MSKLQTAEKM CLLRNSASKC SLFAGAMRSF NEKKAEMITV DGQDIYPNSI LDFVGSSGGA
REFLGRIKSM VVGKLAELTV LREEFLLISS IIFCNPDVFY EPENSAAQSK VASQQQEFTA
ALLHFCMCKY GLNGPSRFTQ LLSLCPIIQR NFDDLQFLTM MFRMKRADIK FRNIVEELI
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