Entry euk:NAC43_ARATH

ID   NAC43_ARATH             Reviewed;         365 AA.
AC   Q84WP6; O81033; Q5M735;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 2.
DT   12-APR-2017, entry version 91.
DE   RecName: Full=NAC domain-containing protein 43;
DE            Short=ANAC043;
DE   AltName: Full=Protein EMBRYO DEFECTIVE 2301;
DE   AltName: Full=Protein NAC SECONDARY WALL THICKENING PROMOTING FACTOR 1;
GN   Name=NAC043; Synonyms=EMB2301, NST1; OrderedLocusNames=At2g46770;
GN   ORFNames=F19D11.5;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L.,
RA   Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L.,
RA   Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H.,
RA   Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D.,
RA   Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M.,
RA   Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Portal (Araport);
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
RA   Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
RA   Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
RA   Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
RA   Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
RA   Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
RA   Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
RA   Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
RA   Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
RA   Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
RA   Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
RA   Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=15029955; DOI=10.1093/dnares/10.6.239;
RA   Ooka H., Satoh K., Doi K., Nagata T., Otomo Y., Murakami K.,
RA   Matsubara K., Osato N., Kawai J., Carninci P., Hayashizaki Y.,
RA   Suzuki K., Kojima K., Takahara Y., Yamamoto K., Kikuchi S.;
RT   "Comprehensive analysis of NAC family genes in Oryza sativa and
RT   Arabidopsis thaliana.";
RL   DNA Res. 10:239-247(2003).
RN   [6]
RP   FUNCTION, AND TISSUE SPECIFICITY.
RX   PubMed=16214898; DOI=10.1105/tpc.105.036004;
RA   Mitsuda N., Seki M., Shinozaki K., Ohme-Takagi M.;
RT   "The NAC transcription factors NST1 and NST2 of Arabidopsis regulate
RT   secondary wall thickenings and are required for anther dehiscence.";
RL   Plant Cell 17:2993-3006(2005).
RN   [7]
RP   FUNCTION, AND TISSUE SPECIFICITY.
RX   PubMed=17237351; DOI=10.1105/tpc.106.047043;
RA   Mitsuda N., Iwase A., Yamamoto H., Yoshida M., Seki M., Shinozaki K.,
RA   Ohme-Takagi M.;
RT   "NAC transcription factors, NST1 and NST3, are key regulators of the
RT   formation of secondary walls in woody tissues of Arabidopsis.";
RL   Plant Cell 19:270-280(2007).
RN   [8]
RP   FUNCTION.
RX   PubMed=17333250; DOI=10.1007/s00425-007-0498-y;
RA   Zhong R., Richardson E.A., Ye Z.-H.;
RT   "Two NAC domain transcription factors, SND1 and NST1, function
RT   redundantly in regulation of secondary wall synthesis in fibers of
RT   Arabidopsis.";
RL   Planta 225:1603-1611(2007).
CC   -!- FUNCTION: Transcription activator of genes involved in
CC       biosynthesis of secondary walls. Together with NST2 and NST3,
CC       required for the secondary cell wall thickening of
CC       sclerenchymatous fibers, secondary xylem (tracheary elements), and
CC       of the anther endocethium, which is necessary for anther
CC       dehiscence. May also regulate the secondary cell wall
CC       lignification of other tissues. {ECO:0000269|PubMed:16214898,
CC       ECO:0000269|PubMed:17237351, ECO:0000269|PubMed:17333250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in various aboveground tissues
CC       undergoing thickening of the lignified secondary wall such as
CC       anthers, filaments of stamens, the base of carpels, styles, the
CC       boundaries between siliques and pedicels, the midrib of leaf
CC       veins, and inflorescence stems, specifically in interfascicular
CC       fibers (sclerenchyma), cells differentiating into vascular
CC       vessels, and xylary fibers (secondary xylem).
CC       {ECO:0000269|PubMed:16214898, ECO:0000269|PubMed:17237351}.
CC   -!- DOMAIN: The NAC domain includes a DNA-binding domain and a
CC       dimerization domain.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC33506.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC005310; AAC33506.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC10750.1; -; Genomic_DNA.
DR   EMBL; BT002931; AAO22745.1; -; mRNA.
DR   EMBL; BT020413; AAV97804.1; -; mRNA.
DR   PIR; T02678; T02678.
DR   RefSeq; NP_182200.2; NM_130243.3.
DR   UniGene; At.36457; -.
DR   ProteinModelPortal; Q84WP6; -.
DR   STRING; 3702.AT2G46770.1; -.
DR   iPTMnet; Q84WP6; -.
DR   PaxDb; Q84WP6; -.
DR   PRIDE; Q84WP6; -.
DR   EnsemblPlants; AT2G46770.1; AT2G46770.1; AT2G46770.
DR   GeneID; 819290; -.
DR   Gramene; AT2G46770.1; AT2G46770.1; AT2G46770.
DR   KEGG; ath:AT2G46770; -.
DR   Araport; AT2G46770; -.
DR   TAIR; locus:2044360; AT2G46770.
DR   eggNOG; ENOG410INES; Eukaryota.
DR   eggNOG; ENOG410YG0P; LUCA.
DR   HOGENOM; HOG000237406; -.
DR   InParanoid; Q84WP6; -.
DR   OMA; HELPSPQ; -.
DR   OrthoDB; EOG09360M1W; -.
DR   PhylomeDB; Q84WP6; -.
DR   PRO; PR:Q84WP6; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   Genevisible; Q84WP6; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; ISS:TAIR.
DR   GO; GO:0010047; P:fruit dehiscence; IMP:TAIR.
DR   GO; GO:0009834; P:plant-type secondary cell wall biogenesis; IMP:TAIR.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   InterPro; IPR003441; NAC-dom.
DR   Pfam; PF02365; NAM; 1.
DR   SUPFAM; SSF101941; SSF101941; 1.
DR   PROSITE; PS51005; NAC; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN         1    365       NAC domain-containing protein 43.
FT                                /FTId=PRO_0000234356.
FT   DOMAIN       16    180       NAC. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00353}.
FT   DNA_BIND    116    186       {ECO:0000255|PROSITE-ProRule:PRU00353}.
FT   CONFLICT    292    292       P -> H (in Ref. 3; AAO22745).
FT                                {ECO:0000305}.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT        16    180       iprf:NAC [T]
FT   MYHIT        17    144       ipfam:NAM [T]
SQ   SEQUENCE   365 AA;  40781 MW;  333921704DA95915 CRC64;
     MMSKSMSISV NGQSQVPPGF RFHPTEEELL QYYLRKKVNS IEIDLDVIRD VDLNKLEPWD
     IQEMCKIGTT PQNDWYFFSH KDKKYPTGTR TNRATAAGFW KATGRDKIIY SNGRRIGMRK
     TLVFYKGRAP HGQKSDWIMH EYRLDDNIIS PEDVTVHEVV SIIGEASQDE GWVVCRIFKK
     KNLHKTLNSP VGGASLSGGG DTPKTTSSQI FNEDTLDQFL ELMGRSCKEE LNLDPFMKLP
     NLESPNSQAI NNCHVSSPDT NHNIHVSNVV DTSFVTSWAA LDRLVASQLN GPTSYSITAV
     NESHVGHDHL ALPSVRSPYP SLNRSASYHA GLTQEYTPEM ELWNTTTSSL SSSPGPFCHV
     SNGSG
//