Entry euk:MU100_SCHPO

ID   MU100_SCHPO             Reviewed;         313 AA.
AC   O14322;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   15-MAR-2017, entry version 73.
DE   RecName: Full=Meiotically up-regulated gene 100 protein, mitochondrial;
DE   Flags: Precursor;
GN   Name=mug100; ORFNames=SPBC16E9.07;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales;
OC   Schizosaccharomycetaceae; Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M.,
RA   Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A.,
RA   Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G.,
RA   Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K.,
RA   James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J.,
RA   Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C.,
RA   Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E.,
RA   Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S.,
RA   Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K.,
RA   Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S.,
RA   Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B.,
RA   Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S.,
RA   Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D.,
RA   Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R.,
RA   Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B.,
RA   Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S.,
RA   Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M.,
RA   Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G.,
RA   Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J.,
RA   Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L.,
RA   Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J.,
RA   Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION IN MEIOSIS.
RX   PubMed=16303567; DOI=10.1016/j.cub.2005.10.038;
RA   Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L.,
RA   Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L.,
RA   San-Segundo P., Smith G.R., Moreno S.;
RT   "A large-scale screen in S. pombe identifies seven novel genes
RT   required for critical meiotic events.";
RL   Curr. Biol. 15:2056-2062(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the
RT   fission yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Has a role in meiosis. {ECO:0000269|PubMed:16303567}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC       {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329671; CAB16899.1; -; Genomic_DNA.
DR   PIR; T39581; T39581.
DR   RefSeq; NP_595789.1; NM_001021690.2.
DR   SMR; O14322; -.
DR   BioGrid; 276684; 2.
DR   MINT; MINT-4672281; -.
DR   SwissPalm; O14322; -.
DR   PRIDE; O14322; -.
DR   EnsemblFungi; SPBC16E9.07.1; SPBC16E9.07.1:pep; SPBC16E9.07.
DR   GeneID; 2540147; -.
DR   KEGG; spo:SPBC16E9.07; -.
DR   EuPathDB; FungiDB:SPBC16E9.07; -.
DR   PomBase; SPBC16E9.07; mug100.
DR   OrthoDB; EOG092C0SZ4; -.
DR   PRO; PR:O14322; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IDA:PomBase.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Complete proteome; Meiosis; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Reference proteome; Transit peptide;
KW   Transmembrane; Transmembrane helix.
FT   TRANSIT       1      ?       Mitochondrion. {ECO:0000255}.
FT   CHAIN         ?    313       Meiotically up-regulated gene 100
FT                                protein, mitochondrial.
FT                                /FTId=PRO_0000278619.
FT   TRANSMEM    147    167       Helical. {ECO:0000255}.
FT   TRANSMEM    178    198       Helical. {ECO:0000255}.
SQ   SEQUENCE   313 AA;  35852 MW;  F05C3F174CCC49CF CRC64;
     MYTTKRFQQL LKEFEVALLL KFSKQLLLLG KIESYLNNGS SMKHEECKSQ IYDCRMAVKI
     YVCSITANKS TNLKHFVRLF FLLGDSERVN LCIKRLIYTF IGSINSVIDK KEDIEQELYS
     SCMHCSIMSP KLQKVMLAQK SLILNKVFDY LFFLYGLSGT SILYTAGDHI RKLDFKDSGF
     ITPFFQLLLL VLLFTLTFKS KHSLNAYSLT ASQFSGHTVC NESSLKPNEN SCDLNLSRTA
     TIKLESAEDD ACQRVLGLIK SYMRPRTLEE LKLEFRFEHK SVQDITTCIL DEVDGVQMAR
     VLEINPDAPI LAF
//