ID METL1_ARATH Reviewed; 775 AA.
AC Q94AI4; Q9T0F6;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 12-APR-2017, entry version 94.
DE RecName: Full=Methyltransferase-like protein 1;
DE EC=2.1.1.-;
DE AltName: Full=Protein EMBRYO DEFECTIVE 1691;
GN Name=EMB1691; OrderedLocusNames=At4g09980; ORFNames=T5L19.110;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G.,
RA Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N.,
RA Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M.,
RA Weichselgartner M., de Simone V., Obermaier B., Mache R., Mueller M.,
RA Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T.,
RA Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I.,
RA Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P.,
RA Langham S.-A., McCullagh B., Bilham L., Robben J.,
RA van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F.,
RA Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E.,
RA Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P.,
RA Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H.,
RA De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R.,
RA van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S.,
RA Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R.,
RA Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S.,
RA Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H.,
RA Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S.,
RA Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A.,
RA Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R.,
RA Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S.,
RA Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E.,
RA Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A.,
RA Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T.,
RA Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C.,
RA Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S.,
RA Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K.,
RA Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L.,
RA Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J.,
RA Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J.,
RA Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D.,
RA Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D.,
RA Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C.,
RA Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C.,
RA Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R.,
RA Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S.,
RA Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A.,
RA Chen E., Marra M.A., Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis
RT thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RG The Arabidopsis Information Portal (Araport);
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
RA Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
RA Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
RA Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
RA Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
RA Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
RA Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
RA Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
RA Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
RA Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
RA Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
RA Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Probable methyltransferase. {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q94AI4-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the MT-A70-like family.
CC {ECO:0000255|PROSITE-ProRule:PRU00489}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB39622.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB78121.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AL049481; CAB39622.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161516; CAB78121.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE82824.1; -; Genomic_DNA.
DR EMBL; AY046016; AAK76690.1; -; mRNA.
DR EMBL; BT000992; AAN41392.1; -; mRNA.
DR PIR; T04002; T04002.
DR RefSeq; NP_001078365.1; NM_001084896.2. [Q94AI4-1]
DR RefSeq; NP_567348.2; NM_117066.4.
DR UniGene; At.33660; -.
DR UniGene; At.69911; -.
DR ProteinModelPortal; Q94AI4; -.
DR SMR; Q94AI4; -.
DR BioGrid; 11888; 1.
DR IntAct; Q94AI4; 1.
DR STRING; 3702.AT4G09980.1; -.
DR iPTMnet; Q94AI4; -.
DR PaxDb; Q94AI4; -.
DR PRIDE; Q94AI4; -.
DR EnsemblPlants; AT4G09980.2; AT4G09980.2; AT4G09980. [Q94AI4-1]
DR GeneID; 826589; -.
DR Gramene; AT4G09980.2; AT4G09980.2; AT4G09980.
DR KEGG; ath:AT4G09980; -.
DR Araport; AT4G09980; -.
DR eggNOG; KOG2097; Eukaryota.
DR eggNOG; ENOG410XQ0H; LUCA.
DR HOGENOM; HOG000237748; -.
DR InParanoid; Q94AI4; -.
DR PhylomeDB; Q94AI4; -.
DR Reactome; R-ATH-72203; Processing of Capped Intron-Containing Pre-mRNA.
DR PRO; PR:Q94AI4; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q94AI4; baseline and differential.
DR Genevisible; Q94AI4; AT.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR007757; MT-A70-like.
DR InterPro; IPR029063; SAM-dependent_MTases.
DR Pfam; PF05063; MT-A70; 1.
DR SUPFAM; SSF53335; SSF53335; 1.
DR PROSITE; PS51143; MT_A70; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Complete proteome; Methyltransferase;
KW Reference proteome; Transferase.
FT CHAIN 1 775 Methyltransferase-like protein 1.
FT /FTId=PRO_0000260073.
FT COMPBIAS 424 562 Pro-rich.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 638 771 ipfam:MT-A70 [T]
FT MYHIT 641 647 ipat:N6_MTASE [T]
FT MYHIT 597 775 iprf:MT_A70 [T]
SQ SEQUENCE 775 AA; 85846 MW; C1A90C40B9DD86DE CRC64;
MKKKQEESSL EKLSTWYQDG EQDGGDRSEK RRMSLKASDF ESSSRSGGSK SKEDNKSVVD
VEHQDRDSKR ERDGRERTHG SSSDSSKRKR WDEAGGLVND GDHKSSKLSD SRHDSGGERV
SVSNEHGESR RDLKSDRSLK TSSRDEKSKS RGVKDDDRGS PLKKTSGKDG SEVVREVGRS
NRSKTPDADY EKEKYSRKDE RSRGRDDGWS DRDRDQEGLK DNWKRRHSSS GDKDQKDGDL
LYDRGREREF PRQGRERSEG ERSHGRLGGR KDGNRGEAVK ALSSGGVSNE NYDVIEIQTK
PHDYVRGESG PNFARMTESG QQPPKKPSNN EEEWAHNQEG RQRSETFGFG SYGEDSRDEA
GEASSDYSGA KARNQRGSTP GRTNFVQTPN RGYQTPQGTR GNRPLRGGKG RPAGGRENQQ
GAIPMPIMGS PFANLGMPPP SPIHSLTPGM SPIPGTSVTP VFMPPFAPTL IWPGARGVDG
NMLPVPPVLS PLPPGPSGPR FPSIGTPPNP NMFFTPPGSD RGGPPNFPGS NISGQMGRGM
PSDKTSGGWV PPRGGGPPGK APSRGEQNDY SQNFVDTGMR PQNFIRELEL TNVEDYPKLR
ELIQKKDEIV SNSASAPMYL KGDLHEVELS PELFGTKFDV ILVDPPWEEY VHRAPGVSDS
MEYWTFEDII NLKIEAIADT PSFLFLWVGD GVGLEQGRQC LKKWGFRRCE DICWVKTNKS
NAAPTLRHDS RTVFQRSKEH CLMGIKGTVR RSTDGHIIHA NIDTDVIIAE EPPYG
//
|
