Legends: 1, REGION Framework-1; 2, REGION Complementarity-determining-1; 3, REGION Framework-2; 4, REGION Complementarity-determining-2; 5, REGION Complementarity-determining-3; 6, REGION Framework-4.
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ID KV3A1_MOUSE Reviewed; 111 AA.
AC P01654;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 10-MAY-2017, entry version 95.
DE RecName: Full=Ig kappa chain V-III region PC 2880/PC 1229;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=103003; DOI=10.1038/276785a0;
RA Weigert M., Gatmaitan L., Loh E., Schilling J., Hood L.E.;
RT "Rearrangement of genetic information may produce immunoglobulin
RT diversity.";
RL Nature 276:785-790(1978).
CC -!- MISCELLANEOUS: The PC 2880 and PC 1229 sequences are identical.
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DR PIR; B93204; KVMS80.
DR PIR; PH0093; PH0093.
DR PIR; PH1079; PH1079.
DR PDB; 1MF2; X-ray; 2.60 A; L/M=1-111.
DR PDB; 1OK5; Model; -; L=1-111.
DR PDB; 2OR9; X-ray; 2.70 A; L/M=1-111.
DR PDB; 2ORB; X-ray; 2.20 A; L/M=1-111.
DR PDBsum; 1MF2; -.
DR PDBsum; 1OK5; -.
DR PDBsum; 2OR9; -.
DR PDBsum; 2ORB; -.
DR ProteinModelPortal; P01654; -.
DR SMR; P01654; -.
DR MaxQB; P01654; -.
DR PeptideAtlas; P01654; -.
DR PRIDE; P01654; -.
DR HOVERGEN; HBG018013; -.
DR EvolutionaryTrace; P01654; -.
DR Proteomes; UP000000589; Unplaced.
DR GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Complete proteome; Direct protein sequencing;
KW Disulfide bond; Immunoglobulin domain; Immunoglobulin V region;
KW Reference proteome.
FT CHAIN 1 >111 Ig kappa chain V-III region PC 2880/PC
FT 1229.
FT /FTId=PRO_0000059777.
FT REGION 1 23 Framework-1.
FT REGION 24 38 Complementarity-determining-1.
FT REGION 39 53 Framework-2.
FT REGION 54 60 Complementarity-determining-2.
FT REGION 61 92 Framework-3.
FT REGION 93 101 Complementarity-determining-3.
FT REGION 102 111 Framework-4.
FT DISULFID 23 92 {ECO:0000255|PROSITE-ProRule:PRU00114}.
FT NON_TER 111 111
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 18 94 ismart:IGv [T]
FT MYHIT 1 93 iprf:IG_LIKE [T]
FT MYHIT 6 110 ipfam:V-set [T]
FT MYHIT 8 111 ismart:IG [T]
SQ SEQUENCE 111 AA; 11980 MW; AFEAC6A9D26FC12D CRC64;
DIVLTQSPAS LAVSLGQRAT ISCRASESVD NYGISFMNWF QQKPGQPPKL LIYAASNQGS
GVPARFSGSG SGTDFSLNIH PMEEDDTAMY FCQQSKEVPW TFGGGTKLEI K
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