MyHits has reached its end of life and no longer provides data or services. Thank you for your support and trust for more than 23 years!
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
- MyHits
| Description | SubName: Full=Zinc finger protein 570 {ECO:0000313|Ensembl:ENSP00000467218}; |
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| MyHits synonyms | K7EP39_HUMAN , K7EP39 , 9F8DB8AFA6AD9ABB |
 Legends: 1, SIGNAL {ECO:0000256|SAM:SignalP}; 2, KRAB. {ECO:0000259|PROSITE:PS50805}; 3, C2H2-type. {ECO:0000259|PROSITE:PS50157}; 4, ismart:ZnF_C2H2 [T]; 5, iprf:ZINC_FINGER_C2H2_2 [T]; 6, ipat:ZINC_FINGER_C2H2_1 [T]; 7, ismart:KRAB [T]; 8, ipfam:KRAB [T].
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ID K7EP39_HUMAN Unreviewed; 592 AA.
AC K7EP39;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 10-MAY-2017, entry version 40.
DE SubName: Full=Zinc finger protein 570 {ECO:0000313|Ensembl:ENSP00000467218};
GN Name=ZNF570 {ECO:0000313|Ensembl:ENSP00000467218};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000467218, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000467218, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000467218}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2012) to UniProtKB.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSP00000467218}.
CC -----------------------------------------------------------------------
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CC Distributed under the Creative Commons Attribution-NoDerivs License
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DR EMBL; AC008806; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001287922.1; NM_001300993.2.
DR UniGene; Hs.126962; -.
DR UniGene; Hs.350875; -.
DR UniGene; Hs.714241; -.
DR ProteinModelPortal; K7EP39; -.
DR STRING; 9606.ENSP00000331540; -.
DR PaxDb; K7EP39; -.
DR PeptideAtlas; K7EP39; -.
DR PRIDE; K7EP39; -.
DR Ensembl; ENST00000586475; ENSP00000467218; ENSG00000171827.
DR GeneID; 148268; -.
DR UCSC; uc010efl.2; human.
DR CTD; 148268; -.
DR HGNC; HGNC:26416; ZNF570.
DR OpenTargets; ENSG00000171827; -.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00840000129704; -.
DR OMA; KGLCSGW; -.
DR OrthoDB; EOG091G02KC; -.
DR GenomeRNAi; 148268; -.
DR Proteomes; UP000005640; Chromosome 19.
DR Bgee; ENSG00000171827; -.
DR ExpressionAtlas; K7EP39; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF01352; KRAB; 1.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 11.
DR SUPFAM; SSF109640; SSF109640; 1.
DR SUPFAM; SSF57667; SSF57667; 6.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 11.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 11.
PE 1: Evidence at protein level;
KW Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW Metal-binding {ECO:0000256|SAAS:SAAS00780264};
KW Proteomics identification {ECO:0000213|PeptideAtlas:K7EP39};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Repeat {ECO:0000256|SAAS:SAAS00780289};
KW Signal {ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|SAAS:SAAS00780264};
KW Zinc-finger {ECO:0000256|SAAS:SAAS00780264}.
FT SIGNAL 1 16 {ECO:0000256|SAM:SignalP}.
FT CHAIN 17 592 {ECO:0000256|SAM:SignalP}.
FT /FTId=PRO_5003904160.
FT DOMAIN 70 141 KRAB. {ECO:0000259|PROSITE:PS50805}.
FT DOMAIN 274 301 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 302 329 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 330 357 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 358 385 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 386 413 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 414 441 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 442 469 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 470 497 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 498 525 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 526 553 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 554 581 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 470 492 ismart:ZnF_C2H2 [T]
FT MYHIT 470 497 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 442 469 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 556 576 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 358 385 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 360 380 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 500 520 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 526 548 ismart:ZnF_C2H2 [T]
FT MYHIT 70 130 ismart:KRAB [T]
FT MYHIT 554 581 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 416 436 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 386 413 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 69 110 ipfam:KRAB [T]
FT MYHIT 444 464 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 302 329 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 358 380 ismart:ZnF_C2H2 [T]
FT MYHIT 276 296 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 386 408 ismart:ZnF_C2H2 [T]
FT MYHIT 414 441 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 274 301 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 526 553 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 302 324 ismart:ZnF_C2H2 [T]
FT MYHIT 388 408 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 274 296 ismart:ZnF_C2H2 [T]
FT MYHIT 472 492 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 70 141 iprf:KRAB [T]
FT MYHIT 554 576 ismart:ZnF_C2H2 [T]
FT MYHIT 414 436 ismart:ZnF_C2H2 [T]
FT MYHIT 304 324 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 528 548 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 330 357 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 498 520 ismart:ZnF_C2H2 [T]
FT MYHIT 332 352 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 330 352 ismart:ZnF_C2H2 [T]
FT MYHIT 498 525 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 442 464 ismart:ZnF_C2H2 [T]
SQ SEQUENCE 592 AA; 68433 MW; 9F8DB8AFA6AD9ABB CRC64;
MCMYLFFLDF SIVGSGLRSG VWVSGSSSQA ICVTPVRVES SEATAISQEK SQEEERMAVG
LLKAMYQELV TFRDVAVDFS QEEWDCLDSS QRHLYSNVML ENYRILVSLG LCFSKPSVIL
LLEQGKAPWM VKRELTKGLC SGWEPICETE ELTPKQDFYE EHQSQKIIET LTSYNLEYSS
LREEWKCEGY FERQPGNQKA CFKEEIITHE EPLFDEREQE YKSWGSFHQN PLLCTQKIIP
KEEKVHKHDT QKRSFKKNLM AIKPKSVCAE KKLLKCNDCE KVFSQSSSLT LHQRIHTGEK
PYKCIECGKA FSQRSNLVQH QRIHTGEKPY ECKECRKAFS QNAHLVQHLR VHTGEKPYEC
KVCRKAFSQF AYLAQHQRVH TGEKPYECIE CGKAFSNRSS IAQHQRVHTG EKPYECNVCG
KAFSLRAYLT VHQRIHTGER PYECKECGKA FSQNSHLAQH QRIHTGEKPY KCQECRKAFS
QIAYLAQHQR VHTGEKPYEC IECGKAFSND SSLTQHQRVH TGEKPYECTV CGKAFSYCGS
LAQHQRIHTG ERPYECKECK KTFRQHAHLA HHQRIHIGES LSPPNPVNHQ VL
//
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