ID H0Y8D0_HUMAN Unreviewed; 80 AA.
AC H0Y8D0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 2.
DT 15-MAR-2017, entry version 25.
DE SubName: Full=Transmembrane protein 222 {ECO:0000313|Ensembl:ENSP00000419878};
GN Name=TMEM222 {ECO:0000313|Ensembl:ENSP00000419878};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000419878, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000419878}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA Waterston R.H., Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2
RT and 4.";
RL Nature 434:724-731(2005).
RN [2] {ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA Porter K.M., Prigmore E.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
RN [3] {ECO:0000213|PubMed:22814378}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E.,
RA Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K.,
RA Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-
RT terminal acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
RN [4] {ECO:0000313|Ensembl:ENSP00000419878}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JAN-2012) to UniProtKB.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSP00000419878}.
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DR EMBL; FO393419; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR ProteinModelPortal; H0Y8D0; -.
DR STRING; 9606.ENSP00000363189; -.
DR PaxDb; H0Y8D0; -.
DR PeptideAtlas; H0Y8D0; -.
DR Ensembl; ENST00000466759; ENSP00000419878; ENSG00000186501.
DR UCSC; uc057duq.1; human.
DR HGNC; HGNC:25363; TMEM222.
DR eggNOG; KOG3150; Eukaryota.
DR eggNOG; ENOG4111G1S; LUCA.
DR GeneTree; ENSGT00390000007371; -.
DR ChiTaRS; TMEM222; human.
DR Proteomes; UP000005640; Chromosome 1.
DR ExpressionAtlas; H0Y8D0; baseline and differential.
DR InterPro; IPR008496; DUF778.
DR PANTHER; PTHR20921; PTHR20921; 1.
DR Pfam; PF05608; DUF778; 1.
PE 1: Evidence at protein level;
KW Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW Proteomics identification {ECO:0000213|MaxQB:H0Y8D0,
KW ECO:0000213|PeptideAtlas:H0Y8D0};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 28 72 ipfam:DUF778 [T]
SQ SEQUENCE 80 AA; 8891 MW; E046A889299AABBE CRC64;
MKQYQGSGGV AMDVERSRFP YCVVWTPIPV LTWFFPIIGH MGICTSTGVI RDFAGPYFVS
EDNMAFGKPA KLTLLPFGNK
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