Legends: 1, N-linked (GlcNAc...) asparagine. {ECO:0000255}; 2, TOPO_DOM Extracellular. {ECO:0000255}; 3, TRANSMEM Helical; Name=1. {ECO:0000255}; 4, TOPO_DOM Cytoplasmic. {ECO:0000255}; 5, TRANSMEM Helical; Name=2. {ECO:0000255}; 6, TRANSMEM Helical; Name=3. {ECO:0000255}; 7, TRANSMEM Helical; Name=4. {ECO:0000255}; 8, TRANSMEM Helical; Name=5. {ECO:0000255}; 9, TRANSMEM Helical; Name=6. {ECO:0000255}; 10, TRANSMEM Helical; Name=7. {ECO:0000255}.
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ID GP173_BOVIN Reviewed; 373 AA.
AC Q5E9H8;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 10-MAY-2017, entry version 80.
DE RecName: Full=Probable G-protein coupled receptor 173;
GN Name=GPR173;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC Pecora; Bovidae; Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Fetal brain;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Orphan receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; BT020942; AAX08959.1; -; mRNA.
DR EMBL; BC133466; AAI33467.1; -; mRNA.
DR RefSeq; NP_001015604.1; NM_001015604.1.
DR RefSeq; XP_005228286.1; XM_005228229.3.
DR UniGene; Bt.66675; -.
DR ProteinModelPortal; Q5E9H8; -.
DR STRING; 9913.ENSBTAP00000023635; -.
DR PaxDb; Q5E9H8; -.
DR PRIDE; Q5E9H8; -.
DR Ensembl; ENSBTAT00000023635; ENSBTAP00000023635; ENSBTAG00000017767.
DR GeneID; 515148; -.
DR KEGG; bta:515148; -.
DR CTD; 54328; -.
DR eggNOG; KOG3656; Eukaryota.
DR eggNOG; ENOG410XRW9; LUCA.
DR GeneTree; ENSGT00870000136395; -.
DR HOGENOM; HOG000231471; -.
DR HOVERGEN; HBG051805; -.
DR InParanoid; Q5E9H8; -.
DR KO; K04300; -.
DR OMA; KRMTFWT; -.
DR OrthoDB; EOG091G0AOZ; -.
DR TreeFam; TF331163; -.
DR Proteomes; UP000009136; Chromosome X.
DR Bgee; ENSBTAG00000017767; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0004968; F:gonadotropin-releasing hormone receptor activity; IBA:GO_Central.
DR GO; GO:2001223; P:negative regulation of neuron migration; IEA:Ensembl.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Complete proteome; Disulfide bond;
KW G-protein coupled receptor; Glycoprotein; Membrane; Receptor;
KW Reference proteome; Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1 373 Probable G-protein coupled receptor 173.
FT /FTId=PRO_0000289297.
FT TOPO_DOM 1 26 Extracellular. {ECO:0000255}.
FT TRANSMEM 27 47 Helical; Name=1. {ECO:0000255}.
FT TOPO_DOM 48 59 Cytoplasmic. {ECO:0000255}.
FT TRANSMEM 60 80 Helical; Name=2. {ECO:0000255}.
FT TOPO_DOM 81 97 Extracellular. {ECO:0000255}.
FT TRANSMEM 98 118 Helical; Name=3. {ECO:0000255}.
FT TOPO_DOM 119 139 Cytoplasmic. {ECO:0000255}.
FT TRANSMEM 140 160 Helical; Name=4. {ECO:0000255}.
FT TOPO_DOM 161 188 Extracellular. {ECO:0000255}.
FT TRANSMEM 189 209 Helical; Name=5. {ECO:0000255}.
FT TOPO_DOM 210 287 Cytoplasmic. {ECO:0000255}.
FT TRANSMEM 288 308 Helical; Name=6. {ECO:0000255}.
FT TOPO_DOM 309 322 Extracellular. {ECO:0000255}.
FT TRANSMEM 323 343 Helical; Name=7. {ECO:0000255}.
FT TOPO_DOM 344 373 Cytoplasmic. {ECO:0000255}.
FT CARBOHYD 3 3 N-linked (GlcNAc...) asparagine.
FT {ECO:0000255}.
FT CARBOHYD 184 184 N-linked (GlcNAc...) asparagine.
FT {ECO:0000255}.
FT DISULFID 96 174 {ECO:0000255|PROSITE-ProRule:PRU00521}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 39 340 iprf:G_PROTEIN_RECEP_F1_2 [T]
FT MYHIT 39 339 ipfam:7tm_1 [T]
SQ SEQUENCE 373 AA; 41479 MW; C3986849BC4AAA3D CRC64;
MANTTGEPEE VSGALSPPSA VAYVKLVLLG LIMCVSLAGN AILSLLVLKD RALHKAPYYF
LLDLCLADGI RSAVCFPFVL ASVRHGSSWT FSALSCKIVA FMAVLFCFHA AFMLFCISVT
RYMAIAHHRF YAKRMTLWTC AAVICMAWTL SVAMAFPPVF DVGTYKFIRE EDQCIFEHRY
FKANDTLGFM LMLAVLMAAT HAVYGKLLLF EYRHRKMKPV QMVPAISQNW TFHGPGATGQ
AAANWIAGFG RGPMPPTLLG IRQNGHAASR RLLGMDEVKG EKQLGRMFYA ITLLFLLLWS
PYIVACYWRV FVKACAVPHR YLATAVWMSF AQAAVNPIVC FLLNKDLKKC LRTHAPCWGT
GGAPAPREPY CVM
//
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