MyHits has reached its end of life and no longer provides data or services. Thank you for your support and trust for more than 23 years!
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
However, the webserver will remain online in its present form at least until end of March 2025.
To ensure the future of MyHits, we would be happy if a person or community would take over the resource or parts of it. Interested? Please contact us (myhits [at] sib.swiss).
Pagni M, Ioannidis V, Cerutti L, Zahn-Zabal M, Jongeneel CV, Hau J, Martin O, Kuznetsov D, Falquet L.
MyHits: improvements to an interactive resource for analyzing protein sequences.
Nucleic Acids Res. 2007 Jul; 35(Web Server issue):W433-7
- MyHits
| Description | RecName: Full=Probable G-protein coupled receptor 156; AltName: Full=GABAB-related G-protein coupled receptor; |
 |
|
| MyHits synonyms | GP156_RAT , Q8K451 , 17E252E8AC8F8FFB |
 Legends: 1, N-linked (GlcNAc...) asparagine. {ECO:0000255}; 2, TOPO_DOM Extracellular. {ECO:0000255}; 3, TRANSMEM Helical; Name=1. {ECO:0000255}; 4, TOPO_DOM Cytoplasmic. {ECO:0000255}; 5, TRANSMEM Helical; Name=2. {ECO:0000255}; 6, TRANSMEM Helical; Name=3. {ECO:0000255}; 7, TRANSMEM Helical; Name=4. {ECO:0000255}; 8, TRANSMEM Helical; Name=5. {ECO:0000255}; 9, TRANSMEM Helical; Name=6. {ECO:0000255}; 10, TRANSMEM Helical; Name=7. {ECO:0000255}; 11, COILED {ECO:0000255}; 12, COMPBIAS Poly-Leu; 13, COMPBIAS Poly-Arg; 14, COMPBIAS Poly-Ser.
| |
ID GP156_RAT Reviewed; 792 AA.
AC Q8K451;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 10-MAY-2017, entry version 73.
DE RecName: Full=Probable G-protein coupled receptor 156;
DE AltName: Full=GABAB-related G-protein coupled receptor;
GN Name=Gpr156; Synonyms=Gababl;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=Sprague-Dawley;
RX PubMed=12591167; DOI=10.1016/S0169-328X(02)00662-9;
RA Calver A.R., Michalovich D., Testa T.T., Robbins M.J., Jaillard C.,
RA Hill J., Szekeres P.G., Charles K.J., Jourdain S., Holbrook J.D.,
RA Boyfield I., Patel N., Medhurst A.D., Pangalos M.N.;
RT "Molecular cloning and characterization of a novel GABA(B)-related G-
RT protein coupled receptor.";
RL Brain Res. Mol. Brain Res. 110:305-317(2003).
CC -!- FUNCTION: Orphan receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- TISSUE SPECIFICITY: Widely expressed throughout the brain and is
CC particularly dense in the olfactory tubercles, islands of Calleja,
CC nucleus accumbens, piriform cortex and all fields of the
CC hippocampus. {ECO:0000269|PubMed:12591167}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC GABA-B receptor subfamily. {ECO:0000305}.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AF488741; AAN03797.1; -; mRNA.
DR RefSeq; NP_695207.1; NM_153295.1.
DR UniGene; Rn.213724; -.
DR STRING; 10116.ENSRNOP00000003773; -.
DR iPTMnet; Q8K451; -.
DR PhosphoSitePlus; Q8K451; -.
DR PaxDb; Q8K451; -.
DR PRIDE; Q8K451; -.
DR GeneID; 260430; -.
DR KEGG; rno:260430; -.
DR UCSC; RGD:708438; rat.
DR CTD; 165829; -.
DR RGD; 708438; Gpr156.
DR eggNOG; KOG1055; Eukaryota.
DR eggNOG; ENOG410XNN1; LUCA.
DR HOGENOM; HOG000168413; -.
DR HOVERGEN; HBG081567; -.
DR InParanoid; Q8K451; -.
DR KO; K04617; -.
DR PhylomeDB; Q8K451; -.
DR PRO; PR:Q8K451; -.
DR Proteomes; UP000002494; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004965; F:G-protein coupled GABA receptor activity; IEA:InterPro.
DR InterPro; IPR002455; GPCR3_GABA-B.
DR InterPro; IPR017978; GPCR_3_C.
DR PANTHER; PTHR10519; PTHR10519; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Coiled coil; Complete proteome;
KW G-protein coupled receptor; Glycoprotein; Membrane; Receptor;
KW Reference proteome; Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1 792 Probable G-protein coupled receptor 156.
FT /FTId=PRO_0000206901.
FT TOPO_DOM 1 49 Extracellular. {ECO:0000255}.
FT TRANSMEM 50 70 Helical; Name=1. {ECO:0000255}.
FT TOPO_DOM 71 86 Cytoplasmic. {ECO:0000255}.
FT TRANSMEM 87 107 Helical; Name=2. {ECO:0000255}.
FT TOPO_DOM 108 118 Extracellular. {ECO:0000255}.
FT TRANSMEM 119 139 Helical; Name=3. {ECO:0000255}.
FT TOPO_DOM 140 164 Cytoplasmic. {ECO:0000255}.
FT TRANSMEM 165 185 Helical; Name=4. {ECO:0000255}.
FT TOPO_DOM 186 222 Extracellular. {ECO:0000255}.
FT TRANSMEM 223 243 Helical; Name=5. {ECO:0000255}.
FT TOPO_DOM 244 257 Cytoplasmic. {ECO:0000255}.
FT TRANSMEM 258 278 Helical; Name=6. {ECO:0000255}.
FT TOPO_DOM 279 287 Extracellular. {ECO:0000255}.
FT TRANSMEM 288 308 Helical; Name=7. {ECO:0000255}.
FT TOPO_DOM 309 792 Cytoplasmic. {ECO:0000255}.
FT COILED 354 390 {ECO:0000255}.
FT COMPBIAS 266 269 Poly-Leu.
FT COMPBIAS 579 582 Poly-Arg.
FT COMPBIAS 724 729 Poly-Ser.
FT CARBOHYD 6 6 N-linked (GlcNAc...) asparagine.
FT {ECO:0000255}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 59 312 iprf:G_PROTEIN_RECEP_F3_4 [T]
FT MYHIT 61 312 ipfam:7tm_3 [T]
SQ SEQUENCE 792 AA; 86426 MW; 17E252E8AC8F8FFB CRC64;
MEPEINCSEF CDSFPGQELD RRPLHDLCKT TITDSQHGSA DISPLSPALL GVIWTFLSCG
LLLVLFFLAF TIRCRKNRIV KMSSPNLNIV TLLGSCLTYS SAYLFGIQDA LVGSSVEALI
QTRLSLLCIG TTLVFGPILG KSWRLYKVFT QRVPDKRVII KDLQLLGLVA ALVVADVILL
VTWVLTDPIQ CLQILGVSMK VTGRDVSCSL TNTHFCASRY SDVWIALVLG CKGLLLLYGA
YLAGLTNHVS SPPVNQSLTI MVGVNLLLLT AGLLFVVTRY LHSWPNLVFG LTSGGIFVCT
TTVNCCVFLP QLRQRKAFEG ENQTIRHMAK YFSTPSKTFR SKFDEDQSCH LRDEXSCMER
LLTEKNAVIE SLQEQVSNAK EKLVKLMSAE CALDSPEWAV PAAASAGGPA ECXATSEKES
GAAAEDSLPA SAASQHMQGP GASRRDXSPS PDQKYDMPLK QFCDHLDMGC SQKPKAEQSE
GPERGNQEPM APGQSLMTDG VACEPHRPRQ NSEVLPERLP RVSSVVREKL QEVLQELDLG
TEAPLSPLPC PQQPWKSNTS GSPQKLSPSK LGFSPYVVRR RRAAQRARSR IPGSVGLKMG
HQANNTVSGS QNGLIVQNRD SPRLDHHNAR SKEPRSSSVK PSPISAPHQR RGSLEGSKQC
ETEPQEARGY SVAFPRQPSA SAPAQSSTAP CLSSXPALPR QRQPLPLLSP GCPSLSSGCY
NLDSESSSSD EFFCRCHRPY CEICFQSSLD SNDSDTSDSD LEQTSGLASW EKLLARSKPV
VNFKDDLKPT LV
//
| |