ID F8VU36_HUMAN Unreviewed; 117 AA.
AC F8VU36;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 02-NOV-2016, entry version 31.
DE SubName: Full=Zinc finger protein 433 {ECO:0000313|Ensembl:ENSP00000447951};
DE Flags: Fragment;
GN Name=ZNF433 {ECO:0000313|Ensembl:ENSP00000447951};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000447951, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000447951, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000447951}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSP00000447951}.
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DR EMBL; AC008770; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC022415; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KC877701; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR ProteinModelPortal; F8VU36; -.
DR STRING; 9606.ENSP00000339767; -.
DR PaxDb; F8VU36; -.
DR Ensembl; ENST00000478765; ENSP00000447951; ENSG00000197647.
DR UCSC; uc060twt.1; human.
DR HGNC; HGNC:20811; ZNF433.
DR OpenTargets; ENSG00000197647; -.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00760000119089; -.
DR Proteomes; UP000005640; Chromosome 19.
DR Bgee; ENSG00000197647; -.
DR ExpressionAtlas; F8VU36; baseline and differential.
DR GO; GO:0005622; C:intracellular; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR InterPro; IPR001909; KRAB.
DR Pfam; PF01352; KRAB; 1.
DR SMART; SM00349; KRAB; 1.
DR SUPFAM; SSF109640; SSF109640; 1.
DR PROSITE; PS50805; KRAB; 1.
PE 4: Predicted;
KW Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1 19 {ECO:0000256|SAM:SignalP}.
FT CHAIN 20 117 {ECO:0000256|SAM:SignalP}.
FT /FTId=PRO_5003379335.
FT DOMAIN 18 96 KRAB. {ECO:0000259|PROSITE:PS50805}.
FT NON_TER 117 117 {ECO:0000313|Ensembl:ENSP00000447951}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 17 58 ipfam:KRAB [T]
FT MYHIT 18 96 iprf:KRAB [T]
FT MYHIT 18 78 ismart:KRAB [T]
SQ SEQUENCE 117 AA; 13603 MW; 0C5BA8358F902A6A CRC64;
MLVLSILLYT CEMFQDSVAF EDVAVTFTQE EWALLDPSQK NLCRDVMQET FRNLASIGKK
WKPQNIYVEY ENLRRNLRIV GERLFESKEG HQHGEILTQV PDDMLKKTTT GVKSCES
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