ID F8VTV7_HUMAN Unreviewed; 207 AA.
AC F8VTV7;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 10-MAY-2017, entry version 34.
DE SubName: Full=Zinc finger protein 433 {ECO:0000313|Ensembl:ENSP00000448099};
DE Flags: Fragment;
GN Name=ZNF433 {ECO:0000313|Ensembl:ENSP00000448099};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000448099, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000448099, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000448099}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSP00000448099}.
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DR EMBL; AC008770; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC022415; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KC877701; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR ProteinModelPortal; F8VTV7; -.
DR SMR; F8VTV7; -.
DR STRING; 9606.ENSP00000339767; -.
DR PaxDb; F8VTV7; -.
DR Ensembl; ENST00000550507; ENSP00000448099; ENSG00000197647.
DR UCSC; uc060twp.1; human.
DR HGNC; HGNC:20811; ZNF433.
DR OpenTargets; ENSG00000197647; -.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00760000119089; -.
DR Proteomes; UP000005640; Chromosome 19.
DR Bgee; ENSG00000197647; -.
DR ExpressionAtlas; F8VTV7; baseline and differential.
DR GO; GO:0005622; C:intracellular; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF01352; KRAB; 1.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF109640; SSF109640; 1.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 4: Predicted;
KW Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW Metal-binding {ECO:0000256|SAAS:SAAS00780264};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Repeat {ECO:0000256|SAAS:SAAS00780289};
KW Zinc {ECO:0000256|SAAS:SAAS00780264};
KW Zinc-finger {ECO:0000256|SAAS:SAAS00780264}.
FT DOMAIN 4 82 KRAB. {ECO:0000259|PROSITE:PS50805}.
FT DOMAIN 139 166 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 167 194 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT NON_TER 207 207 {ECO:0000313|Ensembl:ENSP00000448099}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 167 194 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 169 189 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 141 161 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 167 189 ismart:ZnF_C2H2 [T]
FT MYHIT 4 64 ismart:KRAB [T]
FT MYHIT 4 82 iprf:KRAB [T]
FT MYHIT 139 166 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 3 44 ipfam:KRAB [T]
FT MYHIT 139 161 ismart:ZnF_C2H2 [T]
SQ SEQUENCE 207 AA; 23992 MW; 07C48B5C538D252B CRC64;
MDSVAFEDVA VTFTQEEWAL LDPSQKNLCR DVMQETFRNL ASIGKKWKPQ NIYVEYENLR
RNLRIVGERL FESKEGHQHG EILTQVPDDM LKKTTTGVKS CESSVYGEVG SAHSSLNRHI
RDDTGHKAYE YQEYGQKPYK CKYCKKPFNC LSSVQTHERA HSGRKLYVCE ECGKTFISHS
NLQRHRIMHR GDGPYKCKFC GKALMFL
//
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