ID F6VKC7_MOUSE Unreviewed; 633 AA.
AC F6VKC7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 10-MAY-2017, entry version 49.
DE SubName: Full=Zinc finger protein 988 {ECO:0000313|Ensembl:ENSMUSP00000120413};
GN Name=Zfp988 {ECO:0000313|Ensembl:ENSMUSP00000120413};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000120413, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000120413, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120413,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of
RT the mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000120413}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120413};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000120413}.
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DR EMBL; AL606931; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR ProteinModelPortal; F6VKC7; -.
DR SMR; F6VKC7; -.
DR STRING; 10090.ENSMUSP00000120413; -.
DR PaxDb; F6VKC7; -.
DR PeptideAtlas; F6VKC7; -.
DR Ensembl; ENSMUST00000148762; ENSMUSP00000120413; ENSMUSG00000078498.
DR MGI; MGI:3651985; Zfp988.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00840000129966; -.
DR InParanoid; F6VKC7; -.
DR OMA; KSTATFG; -.
DR OrthoDB; EOG091G02KC; -.
DR TreeFam; TF350864; -.
DR Proteomes; UP000000589; Chromosome 4.
DR Bgee; ENSMUSG00000078498; -.
DR ExpressionAtlas; F6VKC7; baseline and differential.
DR GO; GO:0005622; C:intracellular; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF01352; KRAB; 1.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 14.
DR SUPFAM; SSF109640; SSF109640; 1.
DR SUPFAM; SSF57667; SSF57667; 8.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 14.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 15.
PE 1: Evidence at protein level;
KW Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW Metal-binding {ECO:0000256|SAAS:SAAS00780264};
KW Proteomics identification {ECO:0000213|PeptideAtlas:F6VKC7};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Repeat {ECO:0000256|SAAS:SAAS00780289};
KW Zinc {ECO:0000256|SAAS:SAAS00780264};
KW Zinc-finger {ECO:0000256|SAAS:SAAS00780264}.
FT DOMAIN 13 84 KRAB. {ECO:0000259|PROSITE:PS50805}.
FT DOMAIN 184 211 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 240 267 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 268 295 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 296 323 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 324 351 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 352 379 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 380 407 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 408 435 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 436 463 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 464 491 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 492 519 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 520 547 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 548 575 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 576 603 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 604 631 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 240 262 ismart:ZnF_C2H2 [T]
FT MYHIT 604 631 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 494 514 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 12 52 ipfam:KRAB [T]
FT MYHIT 268 295 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 466 486 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 268 290 ismart:ZnF_C2H2 [T]
FT MYHIT 576 603 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 380 407 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 522 542 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 382 402 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 436 463 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 354 374 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 438 458 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 324 346 ismart:ZnF_C2H2 [T]
FT MYHIT 492 519 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 548 570 ismart:ZnF_C2H2 [T]
FT MYHIT 464 491 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 298 318 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 326 346 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 270 290 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 520 542 ismart:ZnF_C2H2 [T]
FT MYHIT 324 351 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 352 374 ismart:ZnF_C2H2 [T]
FT MYHIT 352 379 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 436 458 ismart:ZnF_C2H2 [T]
FT MYHIT 492 514 ismart:ZnF_C2H2 [T]
FT MYHIT 296 323 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 410 430 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 520 547 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 408 430 ismart:ZnF_C2H2 [T]
FT MYHIT 604 626 ismart:ZnF_C2H2 [T]
FT MYHIT 296 318 ismart:ZnF_C2H2 [T]
FT MYHIT 578 598 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 548 575 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 13 76 ismart:KRAB [T]
FT MYHIT 13 84 iprf:KRAB [T]
FT MYHIT 184 211 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 408 435 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 242 262 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 606 626 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 380 402 ismart:ZnF_C2H2 [T]
FT MYHIT 576 598 ismart:ZnF_C2H2 [T]
FT MYHIT 240 267 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 550 570 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 464 486 ismart:ZnF_C2H2 [T]
SQ SEQUENCE 633 AA; 74121 MW; CA46F7DAE74F2F18 CRC64;
MSVCLVNTPQ GLLTFKDVAL DFSLEEWECL SFAQRSLYMD VMLENYNNLL FVENHCIRGK
NGKVLDQDSQ YIVHEHMNIQ EKSSKWDKLS NVILESLQCT PYKTNHSSDA LQFSNQKRLK
PRNTKEVCKY NDSVNSLSLF STISLNQGIN MQKKKHNRNA ELDNIFVSKH KVMVKKDNIA
GNPYKCSEFH KYLTQRENLQ SQQRIYHGKK PYKSSKSDKC FTHQIHLSIH QGIHTEEIIY
KCSECDKCFK NKFNLTMHQR IHTGEKPYKC SECGKCFTEK SSLRIHQRIH TGEKPYKCSE
CDKCFTKQSN LSIHQRIHTG EKPYKCSECD KCFTQQSCLS IHQRIHTGEK PYKCSECGKC
FTEKSSLRIH QRIHTGEKTY KCSECDKCFT RKFHLGIHQR IHTGEKPYKC SECDKCFTQQ
SNLTIHQRIH TGEKPYKCPE CGKCFTEKSS LRIHQRIHTG EKPYKCSECG KCFTEKSSLR
IHQRIHTGEK PYKCNECGKC FTEKSSLRIH QRIHTGEKPY KCSECGKCFT VKSSLRIHQR
IHTGEKPYKC SECDKCFTKQ SNLSIHQRIH TGEKPYKCSE CEKCFSRKLH LGIHQRIHTG
ERPYKCSECE KCFSRKFHLG IHQRIHTGKK PYK
//
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