Entry euk:F5GZ56_HUMAN

ID   F5GZ56_HUMAN            Unreviewed;       511 AA.
AC   F5GZ56;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   12-APR-2017, entry version 45.
DE   SubName: Full=Intraflagellar transport protein 172 homolog {ECO:0000313|Ensembl:ENSP00000407408};
GN   Name=IFT172 {ECO:0000313|Ensembl:ENSP00000407408};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000407408, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000407408, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000407408}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSP00000407408}.
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DR   EMBL; AC074117; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; F5GZ56; -.
DR   STRING; 9606.ENSP00000260570; -.
DR   MaxQB; F5GZ56; -.
DR   PaxDb; F5GZ56; -.
DR   PeptideAtlas; F5GZ56; -.
DR   Ensembl; ENST00000416524; ENSP00000407408; ENSG00000138002.
DR   UCSC; uc010yls.3; human.
DR   HGNC; HGNC:30391; IFT172.
DR   OpenTargets; ENSG00000138002; -.
DR   eggNOG; KOG3616; Eukaryota.
DR   eggNOG; ENOG410XR2C; LUCA.
DR   GeneTree; ENSGT00440000033648; -.
DR   ChiTaRS; IFT172; human.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000138002; -.
DR   ExpressionAtlas; F5GZ56; baseline and differential.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR017986; WD40_repeat_dom.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:F5GZ56,
KW   ECO:0000213|PeptideAtlas:F5GZ56};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT        81    118       ismart:WD40 [T]
FT   MYHIT       165    202       ismart:WD40 [T]
FT   MYHIT       120    159       ismart:WD40 [T]
FT   MYHIT        34     73       ismart:WD40 [T]
FT   MYHIT       258    293       ismart:WD40 [T]
FT   MYHIT       204    246       ismart:WD40 [T]
SQ   SEQUENCE   511 AA;  57357 MW;  F7AE7109C9FD92D7 CRC64;
     MAWSQNNAKF AVCTVDRVVL LYDEHGERRD KFSTKPADMK YGRKSYMVKG MAFSPDSTKI
     AIGQTDNIIY VYKIGEDWGD KKVICNKFIQ TSAVTCLQWP AEYIIVFGLA EGKVRLANTK
     TNKSSTIYGT ESYVVSLTTN CSGKGILSGH ADGTIVRYFF DDEGSGESQG KLVNHPCPPY
     ALAWATNSIV AAGCDRKIVA YGKEGHMLQT FDYSRDPQER EFTTAVSSPG GQSVVLGSYD
     RLRVFNWIPR RSIWEEAKPK EITNLYTITA LAWKRDGSRL CVGTLCGGVE QFDCCLRRSI
     YKNKFELTYV GPSQVIVKNL SSGTRVVLKS HYGYEVEEVK ILGKERYLVA HTSETLLLGD
     LNTNRLSEIA WQGSGGNEKY FFENENVCMI FNAGELTLVE YGNNDTLGSV RTEFMNPHLI
     SVRINERCQR GTEDNKKLAY LIDIKTIAIV DLIGGYNIGT VSHESRVDWL ELNETGHKLL
     FRDRKLRVRR ATKALGIGWP TEGVRQAATR D
//