ID F1R4A8_DANRE Unreviewed; 428 AA.
AC F1R4A8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 15-MAR-2017, entry version 33.
DE SubName: Full=Keratin 222 {ECO:0000313|Ensembl:ENSDARP00000096591};
DE Flags: Fragment;
GN Name=krt222 {ECO:0000313|Ensembl:ENSDARP00000096591,
GN ECO:0000313|ZFIN:ZDB-GENE-070912-343};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000096591, ECO:0000313|Proteomes:UP000000437};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000096591}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000096591};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000096591, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000096591,
RC ECO:0000313|Proteomes:UP000000437};
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S.,
RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the
RT human genome.";
RL Nature 496:498-503(2013).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685, ECO:0000256|SAAS:SAAS00547919}.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSDARP00000096591}.
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DR EMBL; CU041376; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PaxDb; F1R4A8; -.
DR Ensembl; ENSDART00000105813; ENSDARP00000096591; ENSDARG00000071518.
DR ZFIN; ZDB-GENE-070912-343; krt222.
DR eggNOG; ENOG410IEQR; Eukaryota.
DR eggNOG; ENOG410YA01; LUCA.
DR GeneTree; ENSGT00770000120671; -.
DR OrthoDB; EOG091G0F2M; -.
DR Proteomes; UP000000437; Chromosome 22.
DR ExpressionAtlas; F1R4A8; baseline.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR InterPro; IPR001664; IF.
DR InterPro; IPR018039; Intermediate_filament_CS.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; PTHR23239; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR PROSITE; PS00226; IF; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAAS:SAAS00031873, ECO:0000256|SAM:Coils};
KW Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW Intermediate filament {ECO:0000256|RuleBase:RU000685,
KW ECO:0000256|SAAS:SAAS00031864};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT COILED 35 87 {ECO:0000256|SAM:Coils}.
FT COILED 155 182 {ECO:0000256|SAM:Coils}.
FT COILED 208 263 {ECO:0000256|SAM:Coils}.
FT NON_TER 1 1 {ECO:0000313|Ensembl:ENSDARP00000096591}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 33 263 ismart:Filament [T]
FT MYHIT 250 258 ipat:IF [T]
FT MYHIT 154 262 ipfam:Filament [T]
SQ SEQUENCE 428 AA; 48426 MW; AE249B8CB0CEDCC7 CRC64;
AELLIQSDAV NLKAAHLKNR CETEENLRLL QEQDVLQLKT KKNEVETTNR LLEKQILETE
HELQQTIEEH ERELDQHQQR TAEECDRVLA QVAAGEDGRG MDLSRTSTQC DHSSPAQSSP
DSATPPTQAS GSGPAPKRRP RKDAVSPTVV FPPQVKASDG ALKEARAELA EARKRWHRLQ
VEIESLHALE RSLQSSLRHT QLQYSVQLRD LSRSVKGLES ELETVRDGLE VQKESHNQLL
NTKMRLEKEI ATYRKLLEHE EGRFLNSDGR SVQLKPWKGS DPAPEQNGLP NGCDEGIADP
FFTEKTPKRS PSLQRQRSLV ILTEPVRNKD GDICTVKTQE YLEGNVVRES AEGHGNVETE
KIDKVIRQWE GSFFKGNPKL RKKSVSLRFD LHMAVADEGC SQIKQDSLPN VEVRLVMRRS
RSIPTFAQ
//
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