ID F1QUN0_DANRE Unreviewed; 1008 AA.
AC F1QUN0;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 10-MAY-2017, entry version 41.
DE SubName: Full=Zinc finger protein 574 {ECO:0000313|Ensembl:ENSDARP00000108333};
GN Name=znf574 {ECO:0000313|Ensembl:ENSDARP00000108333,
GN ECO:0000313|ZFIN:ZDB-GENE-100922-259};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000108333, ECO:0000313|Proteomes:UP000000437};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000108333}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000108333};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000108333, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000108333,
RC ECO:0000313|Proteomes:UP000000437};
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S.,
RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the
RT human genome.";
RL Nature 496:498-503(2013).
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSDARP00000108333}.
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DR EMBL; BX005242; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CT583628; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_009290379.1; XM_009292104.2.
DR UniGene; Dr.118434; -.
DR STRING; 7955.ENSDARP00000108333; -.
DR PaxDb; F1QUN0; -.
DR Ensembl; ENSDART00000125158; ENSDARP00000108333; ENSDARG00000087074.
DR GeneID; 798589; -.
DR CTD; 64763; -.
DR ZFIN; ZDB-GENE-100922-259; znf574.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00670000098063; -.
DR InParanoid; F1QUN0; -.
DR OMA; YMCFPCY; -.
DR OrthoDB; EOG091G02KC; -.
DR TreeFam; TF333168; -.
DR Proteomes; UP000000437; Chromosome 16.
DR Bgee; ENSDARG00000087074; -.
DR GO; GO:0030331; F:estrogen receptor binding; IBA:GO_Central.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003714; F:transcription corepressor activity; IBA:GO_Central.
DR GO; GO:0060216; P:definitive hemopoiesis; IMP:ZFIN.
DR GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:GO_Central.
DR GO; GO:0043627; P:response to estrogen; IBA:GO_Central.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR SMART; SM00355; ZnF_C2H2; 16.
DR SUPFAM; SSF57667; SSF57667; 9.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 14.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 16.
PE 1: Evidence at protein level;
KW Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW Proteomics identification {ECO:0000213|PeptideAtlas:F1QUN0};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT DOMAIN 7 34 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 233 260 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 263 290 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 427 455 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 457 484 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 530 557 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 558 585 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 586 608 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 633 660 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 660 687 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 688 715 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 732 759 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 798 825 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 826 853 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 854 881 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 882 909 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 734 754 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 828 848 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 235 256 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 732 754 ismart:ZnF_C2H2 [T]
FT MYHIT 635 655 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 427 455 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 688 715 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 263 290 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 429 450 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 586 608 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 633 660 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 427 450 ismart:ZnF_C2H2 [T]
FT MYHIT 760 784 ismart:ZnF_C2H2 [T]
FT MYHIT 854 876 ismart:ZnF_C2H2 [T]
FT MYHIT 826 848 ismart:ZnF_C2H2 [T]
FT MYHIT 558 580 ismart:ZnF_C2H2 [T]
FT MYHIT 826 853 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 882 909 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 800 820 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 459 479 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 882 904 ismart:ZnF_C2H2 [T]
FT MYHIT 457 479 ismart:ZnF_C2H2 [T]
FT MYHIT 586 608 ismart:ZnF_C2H2 [T]
FT MYHIT 660 682 ismart:ZnF_C2H2 [T]
FT MYHIT 732 759 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 884 904 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 798 825 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 688 708 ismart:ZnF_C2H2 [T]
FT MYHIT 530 552 ismart:ZnF_C2H2 [T]
FT MYHIT 856 876 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 457 484 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 263 285 ismart:ZnF_C2H2 [T]
FT MYHIT 233 260 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 532 552 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 530 557 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 558 585 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 560 580 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 662 682 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 660 687 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 588 608 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 265 285 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 633 655 ismart:ZnF_C2H2 [T]
FT MYHIT 798 820 ismart:ZnF_C2H2 [T]
FT MYHIT 854 881 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 233 256 ismart:ZnF_C2H2 [T]
FT MYHIT 7 34 iprf:ZINC_FINGER_C2H2_2 [T]
SQ SEQUENCE 1008 AA; 111092 MW; 2E5C089D781280BF CRC64;
MESSSVYMCF PCYREFPTLE EVLAHQMTCT AENPQLLPNE TPVEAAAAAA GLPQVAMQAV
TVPQIQTQTA VDLSSLLQQK KTIQADAPRV LYQCADCEVL FDALSLWQQH RKMGCCLETE
PAGEQTEETY EAVAQPQPSQ KENENAVQEQ NTPEQTQVKE VVEIRFESVS QGSVEVAGKV
AAPATSEEEE SSNSVSKEAS ATHEASSVET SAEASSPATR RRGQKKAKPP SSLLCVECGQ
SFSLVPELVT HRRTQHGLKD AIHRCAVCGE GFLNTTLFLY HRRQHRSEVE EEPKQASSGI
PQISTAMLEA PGEGLLLLAT AGEGQSLMEV TTLEQTITET PVAQVEVELE GNEIRGTEQE
PMVEGAEILV EKTEEMLEEH EAPDQEVKME LVIEKVEGNV QMEKIGADEE IQDAVESNAS
ENTSTAFLCH QCGSVFSNDQ ELAKHRKAEH GLEAALHTCG DCGAKFMSTT QFLYHRRQHK
NTTAGHLVTA EVKSRLYTTA ASATGAAAAD GGLEAPAKLS REWSRTALPH ECPHCGQGFT
RRSRLREHVF QHTGEKLFNC KICKKSFPSP ANLLRHSLIH GGSRIYSCPI CDKRFFQPTS
LKRHMMTHQE GVQERRTRGR GKGRGPSSDG RLHICPECPA SFKLEAQLKS HRLLHTSHPF
PCSVCGEAFI RRKELDLHSL IHQDKEPKMC PNCGSQFLNQ TVLDTHLQRC TGEQTGQRKY
KGQGRGKVGG QLECDMCGHR CVTQDGLDLH RLSHTGQTPL RCPLAPCRRR FASSAALGEH
LVAHCCGALG KRNAPRRFTC EFCGKEFAYA STFTVHMRTH TNERPFECAQ CGKRFRQLPH
LQDHERIHSG ERPFTCWVCG KSFSVAARLT EHARVHSGER PYVCPRCPTA FRSRPNLDKH
MRIHANDPVD PTAQNVMDDD AAVQTILLVQ ESASSSPSSS SSVMPVVQEG MFVTEEGGSS
VVFLHPNMSM PTITVPAISV PSMNMPNISV VAGQDVPHTI EVILEETV
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