ID F1QGE8_DANRE Unreviewed; 321 AA.
AC F1QGE8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 2.
DT 12-APR-2017, entry version 43.
DE SubName: Full=Zgc:100911 {ECO:0000313|Ensembl:ENSDARP00000053570};
GN ORFNames=zgc:100911 {ECO:0000313|Ensembl:ENSDARP00000053570,
GN ECO:0000313|ZFIN:ZDB-GENE-040801-162};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000053570, ECO:0000313|Proteomes:UP000000437};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000053570}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000053570};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000053570, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000053570,
RC ECO:0000313|Proteomes:UP000000437};
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S.,
RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the
RT human genome.";
RL Nature 496:498-503(2013).
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSDARP00000053570}.
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DR EMBL; CU905501; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 7955.ENSDARP00000125103; -.
DR Ensembl; ENSDART00000053571; ENSDARP00000053570; ENSDARG00000036897.
DR ZFIN; ZDB-GENE-040801-162; zgc:100911.
DR eggNOG; KOG3058; Eukaryota.
DR eggNOG; ENOG410XNSC; LUCA.
DR GeneTree; ENSGT00390000001630; -.
DR OMA; HITMAKS; -.
DR OrthoDB; EOG091G0J6C; -.
DR TreeFam; TF314547; -.
DR Reactome; R-DRE-1660661; Sphingolipid de novo biosynthesis.
DR Proteomes; UP000000437; Chromosome 23.
DR Bgee; ENSDARG00000036897; -.
DR ExpressionAtlas; F1QGE8; baseline.
DR GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0047493; F:ceramide cholinephosphotransferase activity; IBA:GO_Central.
DR GO; GO:0033188; F:sphingomyelin synthase activity; IBA:GO_Central.
DR GO; GO:0046513; P:ceramide biosynthetic process; IBA:GO_Central.
DR GO; GO:0006686; P:sphingomyelin biosynthetic process; IBA:GO_Central.
DR InterPro; IPR025749; Sphingomyelin_synth-like_dom.
DR Pfam; PF14360; PAP2_C; 1.
PE 4: Predicted;
KW Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 92 112 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 138 159 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 171 189 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 236 255 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 262 283 Helical. {ECO:0000256|SAM:Phobius}.
FT DOMAIN 232 307 PAP2_C. {ECO:0000259|Pfam:PF14360}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 232 307 ipfam:PAP2_C [T]
SQ SEQUENCE 321 AA; 37439 MW; E9CE9842A773FF4A CRC64;
MAQTQLLDEQ DDGQISEYHV MVTVEDSTRP QTPPTGRTHP YQDTPPFSQV DDKPKDSKQR
GFRRIRKNQD YVHITMAKSS TSRLPSEWWK TGIAFIWACF NLVLTTAMIT IVHDRVPDKS
VSPPLPDKFF DYVPRKEWAF RVTEVFGMIL VVLWFIQWLS LKYRAIVGRR FFFLQGLLYM
YRMVTMYITT LPVPSMHMEC APKLQNNSYE KLQRAYQLVT GAGLSITGSH RMCGDFLYSG
HTVMLTLTFL FIYEYSPRSR LWTVYHVICG LLSAMGMICI LMGHEHYSLD VVVAYYITSR
LFYWYHTMAN NQVKTAKLHS V
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