ID E9PWW0_MOUSE Unreviewed; 856 AA.
AC E9PWW0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 10-MAY-2017, entry version 54.
DE SubName: Full=Vomeronasal 2, receptor 103 {ECO:0000313|Ensembl:ENSMUSP00000126756};
GN Name=Vmn2r103 {ECO:0000313|Ensembl:ENSMUSP00000126756,
GN ECO:0000313|MGI:MGI:3644032};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000126756, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000126756, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000126756,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of
RT the mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000126756}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000126756};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane
CC {ECO:0000256|SAAS:SAAS00543559}; Multi-pass membrane protein
CC {ECO:0000256|SAAS:SAAS00543559}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|SAAS:SAAS00547813}.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000126756}.
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DR EMBL; AC113053; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC116463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001098035.1; NM_001104565.1.
DR UniGene; Mm.469855; -.
DR ProteinModelPortal; E9PWW0; -.
DR SMR; E9PWW0; -.
DR STRING; 10090.ENSMUSP00000126756; -.
DR iPTMnet; E9PWW0; -.
DR PhosphoSitePlus; E9PWW0; -.
DR PaxDb; E9PWW0; -.
DR Ensembl; ENSMUST00000172203; ENSMUSP00000126756; ENSMUSG00000091771.
DR GeneID; 627636; -.
DR KEGG; mmu:627636; -.
DR UCSC; uc009vbh.1; mouse.
DR CTD; 627636; -.
DR MGI; MGI:3644032; Vmn2r103.
DR eggNOG; KOG1056; Eukaryota.
DR eggNOG; ENOG410XR6W; LUCA.
DR GeneTree; ENSGT00870000136881; -.
DR InParanoid; E9PWW0; -.
DR OMA; VENHIEM; -.
DR OrthoDB; EOG091G02M6; -.
DR PhylomeDB; E9PWW0; -.
DR TreeFam; TF340115; -.
DR Proteomes; UP000000589; Chromosome 17.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; SSF53822; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|SAAS:SAAS00138752};
KW Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW G-protein coupled receptor {ECO:0000256|SAAS:SAAS00497975};
KW Membrane {ECO:0000256|SAAS:SAAS00138752,
KW ECO:0000256|SAAS:SAAS00425515, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|SAAS:SAAS00497975};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|SAAS:SAAS00497975};
KW Transmembrane {ECO:0000256|SAAS:SAAS00425515,
KW ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAAS:SAAS00425515,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1 19 {ECO:0000256|SAM:SignalP}.
FT CHAIN 20 856 {ECO:0000256|SAM:SignalP}.
FT /FTId=PRO_5003242998.
FT TRANSMEM 583 608 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 620 641 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 653 677 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 697 714 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 747 765 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 777 797 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 803 824 Helical. {ECO:0000256|SAM:Phobius}.
FT DOMAIN 583 847 G_PROTEIN_RECEP_F3_4.
FT {ECO:0000259|PROSITE:PS50259}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 597 830 ipfam:7tm_3 [T]
FT MYHIT 84 427 ipfam:ANF_receptor [T]
FT MYHIT 509 561 ipfam:NCD3G [T]
FT MYHIT 583 847 iprf:G_PROTEIN_RECEP_F3_4 [T]
SQ SEQUENCE 856 AA; 98821 MW; 63B68B69DF4FBDC2 CRC64;
MFTWIFFFRL LQIPKFVSVF TYNISRCYYI VTEEFHHEGD VVVGAFFPLH TFYTEKKMPH
KTVLYQYLDN QIQYNFKNYK YILALQFSIE EINRNPNLLP NTSLGFDFYN VRFTEKYTLD
NVFIWLTALV HRKYFPNYNC KKRNFTAALT GTSWIISAQI GTLLQLFKFP QITFGPYDLL
LSDHGQYPSL YQMAPKDTSL SLAIVSLMAH FRWSWVGLIL PDDHKGNNIV SDFREEMERK
GICLAFVKMI PATWTSHFAK FWEHMDETNV TIVYGDVDSL EGIMRNIEQR LLTQNVWIMN
IEHHVIDRAD YFMLDSFHGS LIFKHNYKEN FEFTKFIQTV NPNKYPEDIY LPKLWHLFFK
CSFADINCNV LENCQTNASL DVFPRHIFDL SMNAESTSIY NGVYAVAHSL HEIRLQQLQM
QPYENGEGMV FFPWQLNRFL KDTEVKDKRC LDWRQTIDTE YDILNFWNLP KGLGLKVKIG
SFSANAPQGQ ELSLSEQMIQ WPEIFSEIPQ SVCSESCEPG FRKVALEGKA ICCYKCTPCG
DNEISNETDV YQCVKCPEGH YANTERNNCF QKSVIFLAYE DPLGMTLASV ALCLSALTVF
VIGIFVKHRD TPIVKANNRA LSYILLLTLT FCFLCSLNFI GQPNTATCIL QQTTFAVTFT
MALATVLAKA ITVVLAFKVS FPGKIVRWLM LSRGPNYIIP ICTLIQLLIC GIWMTTSPPF
IDQDAHTEHG HIIILCNKGS AVAFHSVLGY LCFLALGSYT MAFLSRNLPD TFNESKYLSF
SMLVFFCVWV TFLPVFHSTK GKIMVSMEVF SILASSIALL AFIFGPKCYI ILLKPENNSF
THVRKKTYSR KNYPKI
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