Entry euk:E9PVE7_MOUSE

ID   E9PVE7_MOUSE            Unreviewed;       495 AA.
AC   E9PVE7;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   10-MAY-2017, entry version 42.
DE   SubName: Full=Cilia- and flagella-associated protein 251 {ECO:0000313|Ensembl:ENSMUSP00000126995};
GN   Name=Wdr66 {ECO:0000313|Ensembl:ENSMUSP00000126995,
GN   ECO:0000313|MGI:MGI:1918495};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000126995, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000126995, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000126995,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000213|PubMed:21183079}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and
RT   expression.";
RL   Cell 143:1174-1189(2010).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000126995}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000126995};
RG   Ensembl;
RL   Submitted (MAY-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000126995}.
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DR   EMBL; AC113504; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC163337; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E9PVE7; -.
DR   STRING; 10090.ENSMUSP00000113309; -.
DR   MaxQB; E9PVE7; -.
DR   PaxDb; E9PVE7; -.
DR   Ensembl; ENSMUST00000163092; ENSMUSP00000126995; ENSMUSG00000029442.
DR   MGI; MGI:1918495; Wdr66.
DR   eggNOG; ENOG410JR21; Eukaryota.
DR   eggNOG; ENOG410XQRH; LUCA.
DR   GeneTree; ENSGT00390000013370; -.
DR   Proteomes; UP000000589; Chromosome 5.
DR   Bgee; ENSMUSG00000029442; -.
DR   ExpressionAtlas; E9PVE7; baseline and differential.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR017986; WD40_repeat_dom.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   Proteomics identification {ECO:0000213|MaxQB:E9PVE7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN      255    383       WD_REPEATS_REGION.
FT                                {ECO:0000259|PROSITE:PS50294}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT       146    180       ismart:WD40 [T]
FT   MYHIT       383    426       ismart:WD40 [T]
FT   MYHIT       255    383       iprf:WD_REPEATS_REGION [T]
FT   MYHIT       335    374       ismart:WD40 [T]
FT   MYHIT       292    330       ismart:WD40 [T]
FT   MYHIT       248    287       ismart:WD40 [T]
FT   MYHIT       262    287       ipfam:WD40 [T]
SQ   SEQUENCE   495 AA;  55912 MW;  4F9FCC0BC43824B7 CRC64;
     MRSIAITRDS KFLATISDSA TQKVCIWKWT LAVETPACTL ELPKEYGFQD NLVFNPANNK
     ELVSNSKTQA IYYCWFEDKG ILAHSAPVLT EKTFNKLVGK FSQSVFHLKL PQVLSATKEG
     KLVVWDIHYP SSTSSSAISA FPFIKPRKLV HLQKEAITVL MTIDSYIVTG DIKGNIKFYD
     HTLSVVNWYS NFKLGAIRTL SFSKTIPSLP TEKSNLPTDC TLRGDLFVVR NFIIGTFDAT
     VYHMTVDGTK LEKLFVEPRD AVYAVSCHPY QPLIAVGSVC GMIKVWDFEK KVYLFSRTFE
     KGLGVQCLTY NPEGALLGAG FTEGTVYILD AMSLENESPE PFKYSKSSVS HCCFSHDSNY
     MATADVNFTV AVYMVVVKNG QRVWEYLARL RSHQNSIQSL LFGVHLDSNE PRLLSLGKDR
     FLIEYNLVKS CKDHLDVLDV HRTDQGNYPT CMIWYPPLQG TLPAHLQQRL QSEALQCHHE
     DVQKDAPWTG VWVAY
//