Entry euk:E7F1E4_DANRE

ID   E7F1E4_DANRE            Unreviewed;       800 AA.
AC   E7F1E4;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   10-MAY-2017, entry version 54.
DE   SubName: Full=G protein-coupled receptor 156 {ECO:0000313|Ensembl:ENSDARP00000123809};
GN   Name=gpr156 {ECO:0000313|Ensembl:ENSDARP00000123809,
GN   ECO:0000313|ZFIN:ZDB-GENE-060201-2};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000123809, ECO:0000313|Proteomes:UP000000437};
RN   [1] {ECO:0000313|Ensembl:ENSDARP00000123809}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000123809};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000123809, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000123809,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSDARP00000123809}.
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DR   EMBL; CR759880; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005167483.1; XM_005167426.3.
DR   STRING; 7955.ENSDARP00000123809; -.
DR   Ensembl; ENSDART00000149021; ENSDARP00000123809; ENSDARG00000086215.
DR   GeneID; 101885196; -.
DR   KEGG; dre:101885196; -.
DR   CTD; 165829; -.
DR   ZFIN; ZDB-GENE-060201-2; gpr156.
DR   eggNOG; KOG1055; Eukaryota.
DR   eggNOG; ENOG410XNN1; LUCA.
DR   GeneTree; ENSGT00530000063129; -.
DR   KO; K04617; -.
DR   OMA; YASENTH; -.
DR   OrthoDB; EOG091G03VZ; -.
DR   PhylomeDB; E7F1E4; -.
DR   TreeFam; TF313965; -.
DR   Proteomes; UP000000437; Chromosome 9.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004965; F:G-protein coupled GABA receptor activity; IEA:InterPro.
DR   InterPro; IPR002455; GPCR3_GABA-B.
DR   InterPro; IPR017978; GPCR_3_C.
DR   PANTHER; PTHR10519; PTHR10519; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Membrane {ECO:0000256|SAAS:SAAS00500858, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00500858,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00500858,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     55     78       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     90    110       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    171    192       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    225    245       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    266    287       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    293    315       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       53    318       G_PROTEIN_RECEP_F3_4.
FT                                {ECO:0000259|PROSITE:PS50259}.
FT   COILED      362    396       {ECO:0000256|SAM:Coils}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT        65    318       ipfam:7tm_3 [T]
FT   MYHIT        53    318       iprf:G_PROTEIN_RECEP_F3_4 [T]
SQ   SEQUENCE   800 AA;  88230 MW;  A4B5963B6102E6EA CRC64;
     MEAGLNCSSH CESGVCFINA GVNSQQAWDV LQRLCALTAS SVDVQSRSLS PALRAVVWTL
     LSCGILLALF FLIFTLRFKN NRIVKMSSPN LNVLTLCGSV LTYSSGFLFA IEEKSLLSGA
     GARAVLQARM WTLCIGSSLV FGPILGKTWR LYRVFTQRVP DKRVIIRDIQ LMGLVALLVL
     VDIVVLTAWG LMDPAKCSRS VSAMVKVIDL DSSYSLSQLD SCSSLYSHLW IILISVLKGS
     LLLYGTYLAG LTSNVSLPPV NQSKTIMGAV CLVTMSSAVA VPISLYLYSW PNVVYSVISG
     AIFICTMAIN CLLFVPQLTQ WRHFEEETNS HPSQMAKYFS SPSKTTNSMY SEDEIYYLLG
     ENDSMKRLIN EKNAVIDSLQ EQVNNAKDKL LKLMTASQLL DEREMDSSNT NLNSTSTQTT
     VVSPDSPTLV LKQYSEVAPT RVLSPPPYVP PPPIPIHTTS NATSPEGPGA TDESSPHLRT
     QGNSFLEVES LKGNTEDNIR YSGLGKEISE KPQDVPLDQE KLTEDFPPPA STQFNLPQVE
     SPVPSASVEL PAISPAGRLG FVTNEQLVEI LQDLSIDAVS SSVKSPDRAR SPSINPDELS
     MTLSPQSPLQ FFFPPISPYV MRKRRPPFYS SKGGPPPYYF PGSVPPGRRR GLPDLEKFRD
     DDPITSSTGN PQRHDLLREE RRSKRAEKAQ TQSNSGQDSW QCSSHKCSIT PFMGHVPQPA
     SAGLIEEVKH SKEPYDYSDS DSSSSEDYCY YQRSYCRACH HPYDSTDSLT SGTSDSEDED
     FYRLSHPVVN FKVDVKPTFV
//