Entry euk:E7EVV8_HUMAN

ID   E7EVV8_HUMAN            Unreviewed;       530 AA.
AC   E7EVV8;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   15-MAR-2017, entry version 39.
DE   SubName: Full=Fanconi anemia core complex-associated protein 100 {ECO:0000313|Ensembl:ENSP00000399674};
GN   Name=FAAP100 {ECO:0000313|Ensembl:ENSP00000399674};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000399674, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000399674, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000213|PubMed:18669648}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA   Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA   Elledge S.J., Gygi S.P.;
RT   "A quantitative atlas of mitotic phosphorylation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN   [3] {ECO:0000313|Ensembl:ENSP00000399674}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [4] {ECO:0000213|PubMed:23186163}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=23186163;
RA   Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA   Mohammed S.;
RT   "Toward a comprehensive characterization of a human cancer cell
RT   phosphoproteome.";
RL   J. Proteome Res. 12:260-271(2013).
RN   [5] {ECO:0000213|PubMed:24275569}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA   Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
RA   Wang L., Ye M., Zou H.;
RT   "An enzyme assisted RP-RPLC approach for in-depth analysis of human
RT   liver phosphoproteome.";
RL   J. Proteomics 96:253-262(2014).
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSP00000399674}.
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DR   EMBL; AC137896; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; E7EVV8; -.
DR   STRING; 9606.ENSP00000333283; -.
DR   PaxDb; E7EVV8; -.
DR   PeptideAtlas; E7EVV8; -.
DR   PRIDE; E7EVV8; -.
DR   Ensembl; ENST00000425898; ENSP00000399674; ENSG00000185504.
DR   UCSC; uc002kao.2; human.
DR   HGNC; HGNC:26171; FAAP100.
DR   OpenTargets; ENSG00000185504; -.
DR   eggNOG; ENOG410IEYW; Eukaryota.
DR   eggNOG; ENOG410YKI3; LUCA.
DR   GeneTree; ENSGT00390000016682; -.
DR   ChiTaRS; C17orf70; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000185504; -.
DR   ExpressionAtlas; E7EVV8; baseline and differential.
DR   GO; GO:0005829; C:cytosol; IDA:HPA.
DR   GO; GO:0043240; C:Fanconi anaemia nuclear complex; IEA:InterPro.
DR   GO; GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
DR   GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   InterPro; IPR029251; Faap100.
DR   Pfam; PF15146; FANCAA; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:E7EVV8,
KW   ECO:0000213|PeptideAtlas:E7EVV8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT       110    530       ipfam:FANCAA [T]
SQ   SEQUENCE   530 AA;  56650 MW;  41305A31FABFA9E9 CRC64;
     MHHPAPAWPR CGWCASHTWQ ISLGPRSTSF ILCPLSSCGP RGEVRSDGWR QLPERLGVGG
     AGRNMPLGRG LTLWRGSTPT VCLSWSQARC LPGLSQDVAP GAVGVPPLPG VMSVLRRVSF
     LKKAVDQRNK ALTSLNEAMN VSCALLSSGT GPRPISCTTS TTWSRLQTQD VLMATCVLEN
     SSSFSLDQGW TLCIQVLTSS CALDLDSACS AITYTIPVDQ LGPGARREVT LPLGPGENGG
     LDLPVTVSCT LFYSLREVVG GALAPSDSED PFLDECPSDV LPEQEGVCLP LSRHTVDMLQ
     CLRFPGLAPP HTRAPSPLGP TRDPVATFLE TCREPGSQPA GPASLRAEYL PPSVASIKVS
     AELLRAALKD GHSGVPLCCA TLQWLLAENA AVDVVRARAL SSIQGVAPDG ANVHLIVREV
     AMTDLCPAGP IQAVEIQVES SSLADICRAH HAVVGRMQTM VTEQATQGSS APDLRVQYLR
     QIHANHETLL REVQTLRDRL CTEDEASSCA TAQRLLQVYR QLRHPSLILL
//