Entry euk:E1JJN1_DROME

ID   E1JJN1_DROME            Unreviewed;       151 AA.
AC   E1JJN1;
DT   30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2010, sequence version 1.
DT   10-MAY-2017, entry version 67.
DE   SubName: Full=Bendless, isoform B {ECO:0000313|EMBL:ACZ95287.1};
DE   SubName: Full=Bendless, isoform C {ECO:0000313|EMBL:AFH07377.1};
DE   SubName: Full=Bendless, isoform D {ECO:0000313|EMBL:AGB95382.1};
DE   SubName: Full=Bendless, isoform E {ECO:0000313|EMBL:AGB95383.1};
DE   SubName: Full=CG18319 {ECO:0000313|EMBL:ADF66859.1};
DE   SubName: Full=GEO04036p1 {ECO:0000313|EMBL:ANY27605.1};
GN   Name=ben {ECO:0000313|EMBL:ACZ95287.1,
GN   ECO:0000313|FlyBase:FBgn0000173};
GN   ORFNames=CG18319 {ECO:0000313|EMBL:ADF66859.1,
GN   ECO:0000313|FlyBase:FBgn0000173},
GN   Dmel_CG18319 {ECO:0000313|EMBL:ACZ95287.1};
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227 {ECO:0000313|EMBL:ACZ95287.1, ECO:0000313|Proteomes:UP000000803};
RN   [1] {ECO:0000313|EMBL:ACZ95287.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X.,
RA   Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D.,
RA   Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L.,
RA   Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D.,
RA   Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M.,
RA   Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S.,
RA   Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P.,
RA   Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I.,
RA   Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P.,
RA   de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M.,
RA   Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P.,
RA   Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W.,
RA   Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K.,
RA   Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J.,
RA   Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C.,
RA   Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A.,
RA   Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z.,
RA   Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X.,
RA   Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D.,
RA   Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A.,
RA   Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L.,
RA   Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M.,
RA   Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G.,
RA   Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
RA   Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E.,
RA   Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X.,
RA   Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J.,
RA   Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J.,
RA   Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L.,
RA   Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O.,
RA   Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2] {ECO:0000313|EMBL:ACZ95287.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537568;
RA   Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
RA   Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
RA   George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
RA   Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
RA   Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
RA   Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
RT   "Finishing a whole-genome shotgun: release 3 of the Drosophila
RT   melanogaster euchromatic genome sequence.";
RL   Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
RN   [3] {ECO:0000313|EMBL:ACZ95287.1, ECO:0000313|Proteomes:UP000000803}
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q.,
RA   Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M.,
RA   Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a
RT   systematic review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [4] {ECO:0000313|EMBL:ACZ95287.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537573;
RA   Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
RA   Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M.,
RA   Ashburner M., Celniker S.E.;
RT   "The transposable elements of the Drosophila melanogaster euchromatin:
RT   a genomics perspective.";
RL   Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002).
RN   [5] {ECO:0000313|EMBL:ACZ95287.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=12537574;
RA   Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
RA   Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
RA   Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
RA   Karpen G.H.;
RT   "Heterochromatic sequences in a Drosophila whole-genome shotgun
RT   assembly.";
RL   Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
RN   [6] {ECO:0000313|EMBL:ACZ95287.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
RA   Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
RA   Ashburner M., Anxolabehere D.;
RT   "Combined evidence annotation of transposable elements in genome
RT   sequences.";
RL   PLoS Comput. Biol. 1:166-175(2005).
RN   [7] {ECO:0000313|EMBL:ACZ95287.1}
RP   NUCLEOTIDE SEQUENCE.
RG   Berkeley Drosophila Genome Project;
RA   Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,
RA   Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,
RA   Yu C., Rubin G.;
RT   "Drosophila melanogaster release 4 sequence.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [8] {ECO:0000313|EMBL:ACZ95287.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,
RA   Svirskas R., Rubin G.;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [9] {ECO:0000313|EMBL:ACZ95287.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=17569856; DOI=10.1126/science.1139815;
RA   Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
RT   "The Release 5.1 annotation of Drosophila melanogaster
RT   heterochromatin.";
RL   Science 316:1586-1591(2007).
RN   [10] {ECO:0000313|EMBL:ACZ95287.1, ECO:0000313|Proteomes:UP000000803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
RX   PubMed=17569867; DOI=10.1126/science.1139816;
RA   Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
RA   Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
RA   Dimitri P., Karpen G.H., Celniker S.E.;
RT   "Sequence finishing and mapping of Drosophila melanogaster
RT   heterochromatin.";
RL   Science 316:1625-1628(2007).
RN   [11] {ECO:0000313|EMBL:ADF66859.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ZW149 {ECO:0000313|EMBL:ADF66859.1},
RC   ZW155 {ECO:0000313|EMBL:ADF66860.1},
RC   ZW164 {ECO:0000313|EMBL:ADF66861.1},
RC   ZW165 {ECO:0000313|EMBL:ADF66862.1},
RC   ZW177 {ECO:0000313|EMBL:ADF66863.1},
RC   ZW183 {ECO:0000313|EMBL:ADF66864.1},
RC   ZW184 {ECO:0000313|EMBL:ADF66865.1},
RC   ZW185 {ECO:0000313|EMBL:ADF66866.1},
RC   ZW189 {ECO:0000313|EMBL:ADF66867.1}, and
RC   ZW190 {ECO:0000313|EMBL:ADF66868.1};
RX   PubMed=21383965; DOI=10.1371/journal.pgen.1001315;
RA   Callahan B., Neher R.A., Bachtrog D., Andolfatto P., Shraiman B.I.;
RT   "Correlated evolution of nearby residues in Drosophilid proteins.";
RL   PLoS Genet. 7:E1001315-E1001315(2011).
RN   [12] {ECO:0000313|EMBL:ACZ95287.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Millard Andrew;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [13] {ECO:0000313|EMBL:ANY27605.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family.
CC       {ECO:0000256|PROSITE-ProRule:PRU00388,
CC       ECO:0000256|RuleBase:RU362109, ECO:0000256|SAAS:SAAS00805669}.
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DR   EMBL; AE014298; ACZ95287.1; -; Genomic_DNA.
DR   EMBL; GQ307110; ADF66859.1; -; Genomic_DNA.
DR   EMBL; GQ307111; ADF66860.1; -; Genomic_DNA.
DR   EMBL; GQ307112; ADF66861.1; -; Genomic_DNA.
DR   EMBL; GQ307113; ADF66862.1; -; Genomic_DNA.
DR   EMBL; GQ307114; ADF66863.1; -; Genomic_DNA.
DR   EMBL; GQ307115; ADF66864.1; -; Genomic_DNA.
DR   EMBL; GQ307116; ADF66865.1; -; Genomic_DNA.
DR   EMBL; GQ307117; ADF66866.1; -; Genomic_DNA.
DR   EMBL; GQ307118; ADF66867.1; -; Genomic_DNA.
DR   EMBL; GQ307119; ADF66868.1; -; Genomic_DNA.
DR   EMBL; AE014298; AFH07377.1; -; Genomic_DNA.
DR   EMBL; AE014298; AGB95382.1; -; Genomic_DNA.
DR   EMBL; AE014298; AGB95383.1; -; Genomic_DNA.
DR   EMBL; KX531795; ANY27605.1; -; mRNA.
DR   RefSeq; NP_001162752.1; NM_001169281.2.
DR   RefSeq; NP_001245663.1; NM_001258734.2.
DR   RefSeq; NP_001259540.1; NM_001272611.2.
DR   RefSeq; NP_001259541.1; NM_001272612.2.
DR   RefSeq; NP_511150.1; NM_078595.3.
DR   UniGene; Dm.2088; -.
DR   STRING; 7227.FBpp0073686; -.
DR   EnsemblMetazoa; FBtr0073855; FBpp0073686; FBgn0000173.
DR   EnsemblMetazoa; FBtr0300566; FBpp0289793; FBgn0000173.
DR   EnsemblMetazoa; FBtr0307296; FBpp0298297; FBgn0000173.
DR   EnsemblMetazoa; FBtr0332843; FBpp0305066; FBgn0000173.
DR   EnsemblMetazoa; FBtr0332844; FBpp0305067; FBgn0000173.
DR   GeneID; 32358; -.
DR   KEGG; dme:Dmel_CG18319; -.
DR   CTD; 32358; -.
DR   FlyBase; FBgn0000173; ben.
DR   eggNOG; KOG0417; Eukaryota.
DR   eggNOG; COG5078; LUCA.
DR   KO; K10580; -.
DR   OMA; YFDVEIH; -.
DR   OrthoDB; EOG091G0VPD; -.
DR   GenomeRNAi; 32358; -.
DR   Proteomes; UP000000803; Chromosome X.
DR   Bgee; FBgn0000173; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   CDD; cd00195; UBCc; 1.
DR   Gene3D; 3.10.110.10; -; 1.
DR   InterPro; IPR000608; UBQ-conjugat_E2.
DR   InterPro; IPR023313; UBQ-conjugating_AS.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   Pfam; PF00179; UQ_con; 1.
DR   SUPFAM; SSF54495; SSF54495; 1.
DR   PROSITE; PS00183; UBIQUITIN_CONJUGAT_1; 1.
DR   PROSITE; PS50127; UBIQUITIN_CONJUGAT_2; 1.
PE   1: Evidence at protein level;
KW   ATP-binding {ECO:0000256|RuleBase:RU362109};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000803};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362109};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:E1JJN1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000803};
KW   Ubl conjugation pathway {ECO:0000256|RuleBase:RU362109,
KW   ECO:0000256|SAAS:SAAS00805691}.
FT   DOMAIN        6    138       UBIQUITIN_CONJUGAT_2.
FT                                {ECO:0000259|PROSITE:PS50127}.
FT   ACT_SITE     87     87       Glycyl thioester intermediate.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00388}.
FT   NON_TER     151    151       {ECO:0000313|EMBL:ANY27605.1}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT         7    143       ipfam:UQ_con [T]
FT   MYHIT         6    138       iprf:UBIQUITIN_CONJUGAT_2 [T]
FT   MYHIT        76     91       ipat:UBIQUITIN_CONJUGAT_1 [T]
SQ   SEQUENCE   151 AA;  17236 MW;  1D096E72A7AEA420 CRC64;
     MSSLPRRIIK ETQRLMQEPV PGINAIPDEN NARYFHVIVT GPNDSPFEGG VFKLELFLPE
     DYPMSAPKVR FITKIYHPNI DRLGRICLDV LKDKWSPALQ IRTILLSIQA LLSAPNPDDP
     LANDVAELWK VNEAEAIRNA REWTQKYAVE D
//