ID D4AC93_RAT Unreviewed; 199 AA.
AC D4AC93;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 10-MAY-2017, entry version 54.
DE SubName: Full=Transmembrane protein 223 {ECO:0000313|Ensembl:ENSRNOP00000026141};
GN Name=Tmem223 {ECO:0000313|Ensembl:ENSRNOP00000026141,
GN ECO:0000313|RGD:1582829};
GN Synonyms=LOC686289 {ECO:0000313|RGD:1582829};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000026141, ECO:0000313|Proteomes:UP000002494};
RN [1] {ECO:0000313|Ensembl:ENSRNOP00000026141, ECO:0000313|Proteomes:UP000002494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000026141,
RC ECO:0000313|Proteomes:UP000002494};
RX PubMed=15057822; DOI=10.1038/nature02426;
RG Rat Genome Sequencing Project Consortium;
RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T.,
RA Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A.,
RA Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M.,
RA Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K.,
RA Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S.,
RA Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J.,
RA Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y.,
RA Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A.,
RA Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J.,
RA D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R.,
RA Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A.,
RA Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E.,
RA Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E.,
RA Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D.,
RA Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M.,
RA Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O.,
RA Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O.,
RA Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H.,
RA Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S.,
RA Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J.,
RA Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E.,
RA Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F.,
RA Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K.,
RA Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S.,
RA Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M.,
RA Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M.,
RA Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A.,
RA Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S.,
RA Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G.,
RA Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H.,
RA Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R.,
RA Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M.,
RA Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H.,
RA Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S.,
RA Collins F.S.;
RT "Genome sequence of the Brown Norway rat yields insights into
RT mammalian evolution.";
RL Nature 428:493-521(2004).
RN [2] {ECO:0000313|Ensembl:ENSRNOP00000026141}
RP IDENTIFICATION.
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000026141};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSRNOP00000026141}.
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DR EMBL; AC099294; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001178033.1; NM_001191104.1.
DR UniGene; Rn.1807; -.
DR STRING; 10116.ENSRNOP00000026141; -.
DR PaxDb; D4AC93; -.
DR PeptideAtlas; D4AC93; -.
DR Ensembl; ENSRNOT00000026141; ENSRNOP00000026141; ENSRNOG00000019266.
DR GeneID; 690285; -.
DR KEGG; rno:690285; -.
DR CTD; 79064; -.
DR RGD; 1582829; Tmem223.
DR eggNOG; ENOG410IWJD; Eukaryota.
DR eggNOG; ENOG4111M6M; LUCA.
DR GeneTree; ENSGT00390000012589; -.
DR InParanoid; D4AC93; -.
DR OMA; TSCEHAR; -.
DR OrthoDB; EOG091G0W7I; -.
DR PhylomeDB; D4AC93; -.
DR TreeFam; TF324862; -.
DR PRO; PR:D4AC93; -.
DR Proteomes; UP000002494; Chromosome 1.
DR Bgee; ENSRNOG00000019266; -.
DR Genevisible; D4AC93; RN.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR026100; Tmem223.
DR PANTHER; PTHR14549; PTHR14549; 1.
PE 1: Evidence at protein level;
KW Complete proteome {ECO:0000313|Proteomes:UP000002494};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0000213|PeptideAtlas:D4AC93};
KW Reference proteome {ECO:0000313|Proteomes:UP000002494};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 44 67 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 90 113 Helical. {ECO:0000256|SAM:Phobius}.
SQ SEQUENCE 199 AA; 21674 MW; F6C51DBC52E55ADC CRC64;
MAATLLPRSV SQLLSMLRSG NVHRSLQSGV PRDVLLFEHE RSRFFAILGL FCAGQSIFWT
SLAVAALPKP LIRVPAEAPN RGSLDLRSAL WRYGLAVGCG MMGALVPGAG LLYSLRSVRS
VMLLAGGQQV TLTTYAPFGL GTHFTVPLNQ ISCMAHRGEV PAMLPLKVKG RRFYFLLDKA
GHFPNTLLFD NTVGTYRSL
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