ID D4A1A3_RAT Unreviewed; 519 AA.
AC D4A1A3;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 10-MAY-2017, entry version 64.
DE SubName: Full=Zinc finger and BTB domain-containing 45 {ECO:0000313|Ensembl:ENSRNOP00000033852};
DE SubName: Full=Zinc finger protein 499 (Predicted), isoform CRA_a {ECO:0000313|EMBL:EDL75768.1};
GN Name=Zbtb45 {ECO:0000313|Ensembl:ENSRNOP00000033852,
GN ECO:0000313|RGD:1310920};
GN Synonyms=Zfp499_predicted {ECO:0000313|EMBL:EDL75768.1};
GN ORFNames=rCG_27427 {ECO:0000313|EMBL:EDL75768.1};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000033852, ECO:0000313|Proteomes:UP000002494};
RN [1] {ECO:0000313|Ensembl:ENSRNOP00000033852, ECO:0000313|Proteomes:UP000002494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000033852,
RC ECO:0000313|Proteomes:UP000002494};
RX PubMed=15057822; DOI=10.1038/nature02426;
RG Rat Genome Sequencing Project Consortium;
RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T.,
RA Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A.,
RA Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M.,
RA Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K.,
RA Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S.,
RA Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J.,
RA Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y.,
RA Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A.,
RA Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J.,
RA D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R.,
RA Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A.,
RA Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E.,
RA Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E.,
RA Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D.,
RA Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M.,
RA Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O.,
RA Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O.,
RA Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H.,
RA Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S.,
RA Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J.,
RA Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E.,
RA Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F.,
RA Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K.,
RA Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S.,
RA Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M.,
RA Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M.,
RA Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A.,
RA Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S.,
RA Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G.,
RA Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H.,
RA Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R.,
RA Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M.,
RA Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H.,
RA Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S.,
RA Collins F.S.;
RT "Genome sequence of the Brown Norway rat yields insights into
RT mammalian evolution.";
RL Nature 428:493-521(2004).
RN [2] {ECO:0000313|EMBL:EDL75768.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BN {ECO:0000313|EMBL:EDL75768.1};
RX PubMed=15632090; DOI=10.1101/gr.2889405;
RA Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M.,
RA Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z.,
RA Istrail S., Li P., Sutton G.;
RT "Gene and alternative splicing annotation with AIR.";
RL Genome Res. 15:54-66(2005).
RN [3] {ECO:0000313|EMBL:EDL75768.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BN {ECO:0000313|EMBL:EDL75768.1};
RA Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H.,
RA Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M.,
RA Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L.,
RA Lu F., Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C.,
RA Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Ensembl:ENSRNOP00000033852}
RP IDENTIFICATION.
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000033852};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
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DR EMBL; AABR07002063; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH474090; EDL75768.1; -; Genomic_DNA.
DR EMBL; CH474090; EDL75769.1; -; Genomic_DNA.
DR RefSeq; NP_001100948.1; NM_001107478.1.
DR RefSeq; XP_006228176.1; XM_006228114.3.
DR RefSeq; XP_006228177.1; XM_006228115.3.
DR UniGene; Rn.203449; -.
DR STRING; 10116.ENSRNOP00000033852; -.
DR Ensembl; ENSRNOT00000038860; ENSRNOP00000033852; ENSRNOG00000027459.
DR GeneID; 308366; -.
DR KEGG; rno:308366; -.
DR UCSC; RGD:1310920; rat.
DR CTD; 84878; -.
DR RGD; 1310920; Zbtb45.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00760000119063; -.
DR KO; K10516; -.
DR OMA; APPDCVL; -.
DR OrthoDB; EOG091G0EMJ; -.
DR TreeFam; TF335684; -.
DR Proteomes; UP000002494; Chromosome 1.
DR Bgee; ENSRNOG00000027459; -.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 4.
DR SUPFAM; SSF54695; SSF54695; 1.
DR SUPFAM; SSF57667; SSF57667; 2.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 4.
PE 4: Predicted;
KW Complete proteome {ECO:0000313|Proteomes:UP000002494};
KW Reference proteome {ECO:0000313|Proteomes:UP000002494}.
FT DOMAIN 33 96 BTB (POZ). {ECO:0000259|PROSITE:PS50097}.
FT DOMAIN 411 438 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 439 466 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 467 494 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 494 519 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 439 466 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 411 438 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 467 489 ismart:ZnF_C2H2 [T]
FT MYHIT 33 96 iprf:BTB [T]
FT MYHIT 494 516 ismart:ZnF_C2H2 [T]
FT MYHIT 469 489 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 439 461 ismart:ZnF_C2H2 [T]
FT MYHIT 496 516 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 441 461 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 494 519 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 413 433 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 23 122 ipfam:BTB [T]
FT MYHIT 411 433 ismart:ZnF_C2H2 [T]
FT MYHIT 467 494 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 33 126 ismart:BTB [T]
SQ SEQUENCE 519 AA; 54924 MW; 68D1BC2E5B40D92F CRC64;
MAATEAVHHI HLQNFSRSLL ETLNGQRLGG HFCDVTVRIR EASLRAHRCV LAAGSPFFQD
KLLLGHSEIR VPPVVPAQTV RQLVEFLYSG SLVVAQGEAL QVLTAASVLR IQTVIDECTQ
IIARARVPNP PAPAPLPPPV PPPLAPAQLR HRLRHLLAAR PPGHPNAAHS RKQRQPARLQ
LPAPPTPIKA EGPDTEPVLT AAPEDRGEED DDEETDEETD AEEGEGVGGP GEGQAPPAFP
DCAGGFLTAA ADSAREDPPA STGITDYGGA GRDFLRGTGV TEDVFPDSYV SAWHEEGSGG
PEGCPVETSA PPDCALAGPH PTGVKTPGPP VALFPFHLGA PGPPAPTPPT PSGPAPAPPP
TFYPTLQPDA APSAQLGETP AVPAAPAAQA TAISGTPVRA PGAPGAEQPA YECSHCRKTF
SSRKNYTKHM FIHSGEKPHQ CAVCWRSFSL RDYLLKHMVT HTGVRAFQCA VCAKRFTQKS
SLNVHMRTHR PERAPCPACG KVFSHRALLE RHLAAHPAP
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