ID D3ZVH4_RAT Unreviewed; 313 AA.
AC D3ZVH4;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 10-MAY-2017, entry version 58.
DE SubName: Full=Olfactory receptor 1640 {ECO:0000313|Ensembl:ENSRNOP00000051472};
GN Name=Olr1640 {ECO:0000313|Ensembl:ENSRNOP00000051472,
GN ECO:0000313|RGD:1334263};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000051472, ECO:0000313|Proteomes:UP000002494};
RN [1] {ECO:0000313|Ensembl:ENSRNOP00000051472, ECO:0000313|Proteomes:UP000002494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000051472,
RC ECO:0000313|Proteomes:UP000002494};
RX PubMed=15057822; DOI=10.1038/nature02426;
RG Rat Genome Sequencing Project Consortium;
RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T.,
RA Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A.,
RA Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M.,
RA Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K.,
RA Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S.,
RA Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J.,
RA Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y.,
RA Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A.,
RA Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J.,
RA D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R.,
RA Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A.,
RA Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E.,
RA Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E.,
RA Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D.,
RA Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M.,
RA Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O.,
RA Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O.,
RA Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H.,
RA Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S.,
RA Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J.,
RA Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E.,
RA Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F.,
RA Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K.,
RA Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S.,
RA Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M.,
RA Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M.,
RA Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A.,
RA Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S.,
RA Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G.,
RA Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H.,
RA Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R.,
RA Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M.,
RA Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H.,
RA Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S.,
RA Collins F.S.;
RT "Genome sequence of the Brown Norway rat yields insights into
RT mammalian evolution.";
RL Nature 428:493-521(2004).
RN [2] {ECO:0000313|Ensembl:ENSRNOP00000051472}
RP IDENTIFICATION.
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000051472};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane
CC {ECO:0000256|SAAS:SAAS00521146}; Multi-pass membrane protein
CC {ECO:0000256|SAAS:SAAS00521146}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|SAAS:SAAS00591716}.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSRNOP00000051472}.
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DR EMBL; AC117101; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001000099.1; NM_001000099.1.
DR UniGene; Rn.142432; -.
DR ProteinModelPortal; D3ZVH4; -.
DR STRING; 10116.ENSRNOP00000051472; -.
DR PaxDb; D3ZVH4; -.
DR Ensembl; ENSRNOT00000047436; ENSRNOP00000051472; ENSRNOG00000048857.
DR GeneID; 290049; -.
DR KEGG; rno:290049; -.
DR UCSC; RGD:1334263; rat.
DR CTD; 290049; -.
DR RGD; 1334263; Olr1640.
DR eggNOG; ENOG410IHDC; Eukaryota.
DR eggNOG; ENOG411199R; LUCA.
DR GeneTree; ENSGT00760000119161; -.
DR InParanoid; D3ZVH4; -.
DR KO; K04257; -.
DR OMA; ITVWADP; -.
DR OrthoDB; EOG091G0CZD; -.
DR PhylomeDB; D3ZVH4; -.
DR TreeFam; TF337251; -.
DR Reactome; R-RNO-381753; Olfactory Signaling Pathway.
DR Proteomes; UP000002494; Chromosome 15.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0007608; P:sensory perception of smell; IBA:GO_Central.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|SAAS:SAAS00521172};
KW Complete proteome {ECO:0000313|Proteomes:UP000002494};
KW G-protein coupled receptor {ECO:0000256|SAAS:SAAS00529918};
KW Membrane {ECO:0000256|SAAS:SAAS00520911,
KW ECO:0000256|SAAS:SAAS00521172, ECO:0000256|SAM:Phobius};
KW Olfaction {ECO:0000256|SAAS:SAAS00521184};
KW Receptor {ECO:0000256|SAAS:SAAS00529918};
KW Reference proteome {ECO:0000313|Proteomes:UP000002494};
KW Sensory transduction {ECO:0000256|SAAS:SAAS00521184};
KW Transducer {ECO:0000256|SAAS:SAAS00529918};
KW Transmembrane {ECO:0000256|SAAS:SAAS00520911,
KW ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAAS:SAAS00520911,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 26 49 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 61 83 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 103 121 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 141 163 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 204 227 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 239 261 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 273 291 Helical. {ECO:0000256|SAM:Phobius}.
FT DOMAIN 41 289 G_PROTEIN_RECEP_F1_2.
FT {ECO:0000259|PROSITE:PS50262}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 41 289 iprf:G_PROTEIN_RECEP_F1_2 [T]
SQ SEQUENCE 313 AA; 34958 MW; B7FA7783E15F7E1E CRC64;
MERVNHTLLT EFVLTGVPHP PRLRTFLFVF FLLIYILTQL GNMLILITVC ADTQLHARPM
YVFLGALSVI DMGISTIIVP RLMMNFTPGI KPIPFGGCVA QLYFYHFLGS SQCFLYTTMA
YDRYLAICQP LRYPVLMSAK LSILLVAGAW VAGSIHGAIQ AILTFRLPYC GPNQVDYFFC
DIPAVLKLAC ADTTVNELVT FVDIGVVVAS CFSLILLSYI YIIRAILRIR TADGRRRAFS
TCGAHVTIVT VYYVPCAFIY LRPDSHSILD GAAALFPTAI TPFLNPLIYT LRNQEVKTAL
RRMVGRQSTK SEV
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