Entry euk:CRPM4_ARATH

ID   CRPM4_ARATH             Reviewed;         202 AA.
AC   O23164;
DT   28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 2.
DT   12-APR-2017, entry version 92.
DE   RecName: Full=Cold-regulated 413 plasma membrane protein 4;
DE            Short=AtCOR413-PM4;
GN   OrderedLocusNames=At4g37220; ORFNames=AP22.71, C7A10.140;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9461215; DOI=10.1038/35140;
RA   Bevan M., Bancroft I., Bent E., Love K., Goodman H.M., Dean C.,
RA   Bergkamp R., Dirkse W., van Staveren M., Stiekema W., Drost L.,
RA   Ridley P., Hudson S.-A., Patel K., Murphy G., Piffanelli P.,
RA   Wedler H., Wedler E., Wambutt R., Weitzenegger T., Pohl T., Terryn N.,
RA   Gielen J., Villarroel R., De Clercq R., van Montagu M., Lecharny A.,
RA   Aubourg S., Gy I., Kreis M., Lao N., Kavanagh T., Hempel S.,
RA   Kotter P., Entian K.-D., Rieger M., Schaefer M., Funk B.,
RA   Mueller-Auer S., Silvey M., James R., Monfort A., Pons A.,
RA   Puigdomenech P., Douka A., Voukelatou E., Milioni D., Hatzopoulos P.,
RA   Piravandi E., Obermaier B., Hilbert H., Duesterhoeft A., Moores T.,
RA   Jones J.D.G., Eneva T., Palme K., Benes V., Rechmann S., Ansorge W.,
RA   Cooke R., Berger C., Delseny M., Voet M., Volckaert G., Mewes H.-W.,
RA   Klosterman S., Schueller C., Chalwatzis N.;
RT   "Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of
RT   Arabidopsis thaliana.";
RL   Nature 391:485-488(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617198; DOI=10.1038/47134;
RA   Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G.,
RA   Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N.,
RA   Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M.,
RA   Weichselgartner M., de Simone V., Obermaier B., Mache R., Mueller M.,
RA   Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T.,
RA   Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I.,
RA   Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P.,
RA   Langham S.-A., McCullagh B., Bilham L., Robben J.,
RA   van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F.,
RA   Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E.,
RA   Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA   Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P.,
RA   Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H.,
RA   De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R.,
RA   van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S.,
RA   Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R.,
RA   Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S.,
RA   Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H.,
RA   Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S.,
RA   Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A.,
RA   Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA   Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R.,
RA   Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S.,
RA   Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E.,
RA   Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A.,
RA   Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T.,
RA   Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C.,
RA   Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S.,
RA   Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K.,
RA   Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L.,
RA   Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J.,
RA   Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J.,
RA   Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D.,
RA   Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA   Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA   Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D.,
RA   Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C.,
RA   Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C.,
RA   Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R.,
RA   Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S.,
RA   Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A.,
RA   Chen E., Marra M.A., Martienssen R., McCombie W.R.;
RT   "Sequence and analysis of chromosome 4 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 402:769-777(1999).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Portal (Araport);
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11910074; DOI=10.1126/science.1071006;
RA   Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA   Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M.,
RA   Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T.,
RA   Shibata K., Shinagawa A., Shinozaki K.;
RT   "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL   Science 296:141-145(2002).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
RA   Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
RA   Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
RA   Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
RA   Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
RA   Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
RA   Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
RA   Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
RA   Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
RA   Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
RA   Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
RA   Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [6]
RP   INDUCTION BY SUGARS.
RX   PubMed=16463203; DOI=10.1007/s10265-005-0251-1;
RA   Gonzali S., Loreti E., Solfanelli C., Novi G., Alpi A., Perata P.;
RT   "Identification of sugar-modulated genes and evidence for in vivo
RT   sugar sensing in Arabidopsis.";
RL   J. Plant Res. 119:115-123(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- INDUCTION: Repressed by sucrose, glucose and fructose. Slightly
CC       induced by turanose and mannitol. {ECO:0000269|PubMed:16463203}.
CC   -!- SIMILARITY: Belongs to the Cold-regulated 413 protein family.
CC       {ECO:0000305}.
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DR   EMBL; Z99707; CAB16776.1; -; Genomic_DNA.
DR   EMBL; AL161591; CAB80388.1; -; Genomic_DNA.
DR   EMBL; CP002687; AEE86769.1; -; Genomic_DNA.
DR   EMBL; AK117399; BAC42066.1; -; mRNA.
DR   EMBL; BT005584; AAO64004.1; -; mRNA.
DR   PIR; G85439; G85439.
DR   RefSeq; NP_195439.1; NM_119885.3.
DR   UniGene; At.31263; -.
DR   ProteinModelPortal; O23164; -.
DR   BioGrid; 15157; 21.
DR   STRING; 3702.AT4G37220.1; -.
DR   PaxDb; O23164; -.
DR   EnsemblPlants; AT4G37220.1; AT4G37220.1; AT4G37220.
DR   GeneID; 829876; -.
DR   Gramene; AT4G37220.1; AT4G37220.1; AT4G37220.
DR   KEGG; ath:AT4G37220; -.
DR   Araport; AT4G37220; -.
DR   TAIR; locus:2115010; AT4G37220.
DR   eggNOG; ENOG410JWVD; Eukaryota.
DR   eggNOG; ENOG41104JT; LUCA.
DR   HOGENOM; HOG000239742; -.
DR   InParanoid; O23164; -.
DR   OMA; YLFHEHI; -.
DR   OrthoDB; EOG09360RWR; -.
DR   PhylomeDB; O23164; -.
DR   PRO; PR:O23164; -.
DR   Proteomes; UP000006548; Chromosome 4.
DR   ExpressionAtlas; O23164; baseline and differential.
DR   Genevisible; O23164; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009750; P:response to fructose; IEP:TAIR.
DR   GO; GO:0009749; P:response to glucose; IEP:TAIR.
DR   GO; GO:0009744; P:response to sucrose; IEP:TAIR.
DR   InterPro; IPR008892; COR413.
DR   Pfam; PF05562; WCOR413; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Complete proteome; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN         1    202       Cold-regulated 413 plasma membrane
FT                                protein 4.
FT                                /FTId=PRO_0000420443.
FT   TOPO_DOM      1     42       Extracellular. {ECO:0000255}.
FT   TRANSMEM     43     63       Helical. {ECO:0000255}.
FT   TOPO_DOM     64     72       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM     73     93       Helical. {ECO:0000255}.
FT   TOPO_DOM     94     97       Extracellular. {ECO:0000255}.
FT   TRANSMEM     98    118       Helical. {ECO:0000255}.
FT   TOPO_DOM    119    119       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    120    140       Helical. {ECO:0000255}.
FT   TOPO_DOM    141    145       Extracellular. {ECO:0000255}.
FT   TRANSMEM    146    166       Helical. {ECO:0000255}.
FT   TOPO_DOM    167    181       Cytoplasmic. {ECO:0000255}.
FT   TRANSMEM    182    202       Helical. {ECO:0000255}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT         9    189       ipfam:WCOR413 [T]
SQ   SEQUENCE   202 AA;  22632 MW;  F453FAE0548C6B47 CRC64;
     MGRGEFLAMK TEENAANLIN SDMNEFVAAA KKLVKDVGML GGVGFGTSVL QWAASIFAIY
     LLILDRTNWK TKMLTTLLVP YIFFTLPSVI FQFFSGDFGK WIALIAIIVR LFFPKEFPEW
     LEIPVALILI VVVSPSLIAW TLRESWVGAV ICLVIACYLF HEHIKASGGF KNSFTQKNGI
     SNTIGIVALL VYPVWTIFFH IF
//