ID CC172_HUMAN Reviewed; 258 AA.
AC P0C7W6;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 22-JUL-2008, sequence version 1.
DT 15-MAR-2017, entry version 69.
DE RecName: Full=Coiled-coil domain-containing protein 172;
GN Name=CCDC172; Synonyms=C10orf96;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164054; DOI=10.1038/nature02462;
RA Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,
RA Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,
RA Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,
RA Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,
RA Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,
RA Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J.,
RA Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D.,
RA Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L.,
RA Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S.,
RA Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L.,
RA Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J.,
RA Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M.,
RA Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S.,
RA Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M.,
RA Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A.,
RA Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T.,
RA Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I.,
RA Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T.,
RA Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,
RA Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W.,
RA Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H.,
RA Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L.,
RA Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K.,
RA Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T.,
RA Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;
RT "The DNA sequence and comparative analysis of human chromosome 10.";
RL Nature 429:375-381(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA
RT project: the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q13561:DCTN2; NbExp=3; IntAct=EBI-2548868, EBI-715074;
CC Q8NE31:FAM13C; NbExp=3; IntAct=EBI-2548868, EBI-751248;
CC Q8N4P3:HDDC3; NbExp=3; IntAct=EBI-2548868, EBI-750003;
CC Q9H1K1:ISCU; NbExp=3; IntAct=EBI-2548868, EBI-1047335;
CC Q9H788:SH2D4A; NbExp=3; IntAct=EBI-2548868, EBI-747035;
CC Q969G3:SMARCE1; NbExp=3; IntAct=EBI-2548868, EBI-455078;
CC Q9BT92:TCHP; NbExp=5; IntAct=EBI-2548868, EBI-740781;
CC D3DUQ6:TEAD4; NbExp=3; IntAct=EBI-2548868, EBI-10176734;
CC O14530:TXNDC9; NbExp=3; IntAct=EBI-2548868, EBI-707554;
CC -!- SIMILARITY: Belongs to the CCDC172 family. {ECO:0000305}.
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DR EMBL; AC011328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC044830; AAH44830.1; -; mRNA.
DR CCDS; CCDS31291.1; -.
DR RefSeq; NP_940917.1; NM_198515.2.
DR RefSeq; XP_016871695.1; XM_017016206.1.
DR UniGene; Hs.233407; -.
DR ProteinModelPortal; P0C7W6; -.
DR SMR; P0C7W6; -.
DR BioGrid; 131893; 17.
DR IntAct; P0C7W6; 23.
DR MINT; MINT-8417611; -.
DR STRING; 9606.ENSP00000329860; -.
DR iPTMnet; P0C7W6; -.
DR PhosphoSitePlus; P0C7W6; -.
DR BioMuta; CCDC172; -.
DR DMDM; 206557852; -.
DR MaxQB; P0C7W6; -.
DR PaxDb; P0C7W6; -.
DR PeptideAtlas; P0C7W6; -.
DR PRIDE; P0C7W6; -.
DR DNASU; 374355; -.
DR Ensembl; ENST00000333254; ENSP00000329860; ENSG00000182645.
DR GeneID; 374355; -.
DR KEGG; hsa:374355; -.
DR UCSC; uc001lck.3; human.
DR CTD; 374355; -.
DR DisGeNET; 374355; -.
DR GeneCards; CCDC172; -.
DR HGNC; HGNC:30524; CCDC172.
DR neXtProt; NX_P0C7W6; -.
DR OpenTargets; ENSG00000182645; -.
DR PharmGKB; PA134867240; -.
DR eggNOG; ENOG410IWRG; Eukaryota.
DR eggNOG; ENOG4112A44; LUCA.
DR GeneTree; ENSGT00390000005203; -.
DR HOGENOM; HOG000111699; -.
DR HOVERGEN; HBG106901; -.
DR InParanoid; P0C7W6; -.
DR OMA; EAICTTK; -.
DR OrthoDB; EOG091G0OD3; -.
DR PhylomeDB; P0C7W6; -.
DR TreeFam; TF333231; -.
DR GenomeRNAi; 374355; -.
DR PRO; PR:P0C7W6; -.
DR Proteomes; UP000005640; Chromosome 10.
DR Bgee; ENSG00000182645; -.
DR CleanEx; HS_C10orf96; -.
DR Genevisible; P0C7W6; HS.
DR InterPro; IPR029618; CCDC172.
DR PANTHER; PTHR22419:SF3; PTHR22419:SF3; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Complete proteome; Reference proteome.
FT CHAIN 1 258 Coiled-coil domain-containing protein
FT 172.
FT /FTId=PRO_0000344513.
FT COILED 13 90 {ECO:0000255}.
FT COILED 123 191 {ECO:0000255}.
FT COILED 226 256 {ECO:0000255}.
SQ SEQUENCE 258 AA; 31035 MW; 9CFC9C42B13486B3 CRC64;
MSLESLFQHI IFTEHQAEES RRLMREVRSE ITRCREKIKK ATEELNEEKI KLESKVQQFF
EKSFFLQLLK AHENALEKQY SEITNHRNML LQTFEAIKKQ MIEEEDKFIK EITDFNNDYE
ITKKRELLMK ENVKIEISDL ENQANMLKSE MKSMEHDSSQ LNELQKQKSE LIQELFTLQR
KLKVFEDEEN ESICTTKYLE AEKIKISEKP QNDTECLRLK KELELYKEDD MESVYEALQT
EIEFLELTLA QKDLQESK
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