Entry euk:CC159_MOUSE

ID   CC159_MOUSE             Reviewed;         411 AA.
AC   Q8C963; Q0VBB7; Q9CXZ5; Q9D4W5;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   10-MAY-2017, entry version 85.
DE   RecName: Full=Coiled-coil domain-containing protein 159;
GN   Name=Ccdc159;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3).
RC   STRAIN=C57BL/6J; TISSUE=Cerebellum, Liver, and Testis;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
RA   Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
RA   Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
RA   Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
RA   Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
RA   Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
RA   di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
RA   Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
RA   Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
RA   Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
RA   Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
RA   Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
RA   Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
RA   Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
RA   Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
RA   Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
RA   Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
RA   Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
RA   Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
RA   Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
RA   Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
RA   Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
RA   Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
RA   Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
RA   Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
RA   Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
RA   Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
RA   Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
RA   Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
RA   Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
RA   Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
RA   Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=1;
CC         IsoId=Q8C963-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q8C963-2; Sequence=VSP_033427;
CC       Name=3;
CC         IsoId=Q8C963-3; Sequence=VSP_033428, VSP_033429;
CC         Note=No experimental confirmation available.;
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DR   EMBL; AK011114; BAB27409.1; -; mRNA.
DR   EMBL; AK016073; BAB30102.1; -; mRNA.
DR   EMBL; AK042884; BAC31391.1; -; mRNA.
DR   EMBL; BC120702; AAI20703.1; -; mRNA.
DR   EMBL; BC120704; AAI20705.1; -; mRNA.
DR   CCDS; CCDS40557.1; -. [Q8C963-2]
DR   CCDS; CCDS52738.1; -. [Q8C963-1]
DR   RefSeq; NP_001158086.1; NM_001164614.1. [Q8C963-1]
DR   RefSeq; NP_080253.2; NM_025977.3. [Q8C963-2]
DR   UniGene; Mm.154305; -.
DR   ProteinModelPortal; Q8C963; -.
DR   SMR; Q8C963; -.
DR   iPTMnet; Q8C963; -.
DR   PhosphoSitePlus; Q8C963; -.
DR   PaxDb; Q8C963; -.
DR   PRIDE; Q8C963; -.
DR   Ensembl; ENSMUST00000006403; ENSMUSP00000006403; ENSMUSG00000006241. [Q8C963-2]
DR   Ensembl; ENSMUST00000170304; ENSMUSP00000126474; ENSMUSG00000006241. [Q8C963-1]
DR   Ensembl; ENSMUST00000214734; ENSMUSP00000150744; ENSMUSG00000006241. [Q8C963-3]
DR   GeneID; 67119; -.
DR   KEGG; mmu:67119; -.
DR   UCSC; uc009omx.1; mouse. [Q8C963-2]
DR   UCSC; uc009omy.2; mouse. [Q8C963-3]
DR   UCSC; uc009omz.2; mouse. [Q8C963-1]
DR   CTD; 126075; -.
DR   MGI; MGI:1914369; Ccdc159.
DR   eggNOG; ENOG410J016; Eukaryota.
DR   eggNOG; ENOG41114KW; LUCA.
DR   GeneTree; ENSGT00390000008201; -.
DR   HOGENOM; HOG000139146; -.
DR   HOVERGEN; HBG056552; -.
DR   InParanoid; Q8C963; -.
DR   OMA; WPETEEI; -.
DR   OrthoDB; EOG091G0A8B; -.
DR   PhylomeDB; Q8C963; -.
DR   TreeFam; TF337495; -.
DR   PRO; PR:Q8C963; -.
DR   Proteomes; UP000000589; Chromosome 9.
DR   Bgee; ENSMUSG00000006241; -.
DR   Genevisible; Q8C963; MM.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Coiled coil; Complete proteome;
KW   Reference proteome.
FT   CHAIN         1    411       Coiled-coil domain-containing protein
FT                                159.
FT                                /FTId=PRO_0000332997.
FT   COILED      269    305       {ECO:0000255}.
FT   VAR_SEQ       1     12       MGEHERVVCCSS -> MNGC (in isoform 2).
FT                                {ECO:0000303|PubMed:15489334,
FT                                ECO:0000303|PubMed:16141072}.
FT                                /FTId=VSP_033427.
FT   VAR_SEQ     263    267       SKKFL -> RGPGG (in isoform 3).
FT                                {ECO:0000303|PubMed:16141072}.
FT                                /FTId=VSP_033428.
FT   VAR_SEQ     268    411       Missing (in isoform 3).
FT                                {ECO:0000303|PubMed:16141072}.
FT                                /FTId=VSP_033429.
FT   CONFLICT     55     55       E -> D (in Ref. 1; BAB27409).
FT                                {ECO:0000305}.
SQ   SEQUENCE   411 AA;  46342 MW;  8E9CA2940FC293AA CRC64;
     MGEHERVVCC SSDSLLAGLS RDSDDCVSHL CTPPLLAITS WAAKERSQYS PPPGEPGPSS
     DKALDCMTHW SRVLEPEIVN TASEQAGKSG AWEKEWDSEP QPHEGTPCSS SDVNKDHYHD
     QDLVKRNHCV AKKSLEPSSA KVKVKNTMII PDSQKLLRCE LESLRSQLQA QSKAFEFLNH
     SVTMLEKESC LQQIKIQQLE EVLSPTSRQG EKYGRKWSTE QELYGALAQG LQGLQKTLKE
     GEELQRARTT RCLQLLAREI RDSKKFLWEE LELVREEVTF IYQKLQDQED EISENLLNIQ
     KMQKTQVKCR KVLTKMKQQA YDSWPEAEGV PTEGNGCCKD DLQKELGDIW SAVHSLQSSI
     DCLALSMGTR PRASSLRGQK GHQCKSSQCP SWDSDSDWER PFSKSGSYPP A
//