Entry euk:B3DJF2_DANRE

ID   B3DJF2_DANRE            Unreviewed;       674 AA.
AC   B3DJF2;
DT   22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2008, sequence version 1.
DT   10-MAY-2017, entry version 72.
DE   SubName: Full=WD and tetratricopeptide repeats 1 {ECO:0000313|Ensembl:ENSDARP00000099567};
DE   SubName: Full=Zgc:194983 {ECO:0000313|EMBL:AAI63463.1};
GN   Name=wdtc1 {ECO:0000313|Ensembl:ENSDARP00000099567,
GN   ECO:0000313|ZFIN:ZDB-GENE-030131-3224};
GN   ORFNames=zgc:194983 {ECO:0000313|EMBL:AAI63463.1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI63463.1};
RN   [1] {ECO:0000313|EMBL:AAI63463.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000099567}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000099567};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000099567, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000099567,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
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DR   EMBL; CU861891; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC163463; AAI63463.1; -; mRNA.
DR   RefSeq; NP_001124078.1; NM_001130606.1.
DR   UniGene; Dr.78779; -.
DR   STRING; 7955.ENSDARP00000099567; -.
DR   Ensembl; ENSDART00000113358; ENSDARP00000099567; ENSDARG00000059760.
DR   GeneID; 570606; -.
DR   KEGG; dre:570606; -.
DR   CTD; 23038; -.
DR   ZFIN; ZDB-GENE-030131-3224; wdtc1.
DR   eggNOG; KOG1310; Eukaryota.
DR   eggNOG; KOG1334; Eukaryota.
DR   eggNOG; ENOG410XWAR; LUCA.
DR   GeneTree; ENSGT00530000062951; -.
DR   HOGENOM; HOG000231334; -.
DR   HOVERGEN; HBG059105; -.
DR   KO; K11807; -.
DR   OMA; IWDPFRK; -.
DR   OrthoDB; EOG091G08IE; -.
DR   TreeFam; TF320710; -.
DR   Proteomes; UP000000437; Chromosome 16.
DR   Bgee; ENSDARG00000059760; -.
DR   Gene3D; 1.25.40.10; -; 1.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR013026; TPR-contain_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR017986; WD40_repeat_dom.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   SUPFAM; SSF50978; SSF50978; 3.
DR   PROSITE; PS50293; TPR_REGION; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN       49    178       WD_REPEATS_REGION.
FT                                {ECO:0000259|PROSITE:PS50294}.
FT   REPEAT       49     81       WD. {ECO:0000256|PROSITE-
FT                                ProRule:PRU00221}.
FT   REPEAT       92    135       WD. {ECO:0000256|PROSITE-
FT                                ProRule:PRU00221}.
FT   DOMAIN      395    465       TPR_REGION.
FT                                {ECO:0000259|PROSITE:PS50293}.
FT   DOMAIN      527    614       WD_REPEATS_REGION.
FT                                {ECO:0000259|PROSITE:PS50294}.
FT   REPEAT      543    572       WD. {ECO:0000256|PROSITE-
FT                                ProRule:PRU00221}.
FT   REPEAT      573    605       WD. {ECO:0000256|PROSITE-
FT                                ProRule:PRU00221}.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT       520    563       ismart:WD40 [T]
FT   MYHIT        85    126       ismart:WD40 [T]
FT   MYHIT       543    572       iprf:WD_REPEATS_2 [T]
FT   MYHIT       525    562       ipfam:WD40 [T]
FT   MYHIT       568    605       ipfam:WD40 [T]
FT   MYHIT        92    135       iprf:WD_REPEATS_2 [T]
FT   MYHIT       573    605       iprf:WD_REPEATS_2 [T]
FT   MYHIT        49    178       iprf:WD_REPEATS_REGION [T]
FT   MYHIT       395    465       iprf:TPR_REGION [T]
FT   MYHIT       566    605       ismart:WD40 [T]
FT   MYHIT       527    614       iprf:WD_REPEATS_REGION [T]
FT   MYHIT        49     81       iprf:WD_REPEATS_2 [T]
FT   MYHIT        48     81       ipfam:WD40 [T]
FT   MYHIT       183    219       ismart:WD40 [T]
FT   MYHIT        42     81       ismart:WD40 [T]
FT   MYHIT       129    169       ismart:WD40 [T]
SQ   SEQUENCE   674 AA;  75740 MW;  57FC97B536E7B85A CRC64;
     MTCCETMTLR NITGDLLHRQ IRENRALDFQ RHYHVTDPFI KRLGLEAELQ GHSGCVNCLE
     WNEKGDLLAS GSDDQHAIIW DPFRHSKLIT MHTGHAANIF SVKFLPHSDD RILITGAADT
     KVHVHDVTAK ETIHMFSDHT NRVKRIATAP MWPNTFWSAA EDGLIRQYDL RESSKRSDVL
     IDLTEYCGQL VEAKCLAVNP RDNNYLAVGA NGPFVRLYDI RMIHNHRKSL SQSSSAGVHT
     FCDKRKSIPD GAGQYYVAGH LPVKLPDYNN RLRVLVATYV TFSPDGTELL VNMGGEQVYL
     FDLTFKQRPY TFLLPKKCHS STDVQNGKTT NGVSNGIHLP ASRLKLAKVS SSGSGDLPLH
     LERIKQRAND AFARQQWTQA IQLYSLGIHE AGPNAMLYGN RAAAYMKRKW DGDHYDALRD
     CLKALSLNPG HLKAHFRLAR CLFELKYVAE ALECLNDFKG KFPEQAHSSA CDALDKDIKA
     ALFSKTDASD DKKGNSSIRF HNFSRKESIP EDEIVLRERS FDYKHRYCGH CNTTTDIKEA
     NFFGSKGQYI VSGSDDGSFF IWEKETTNLV RILQGDESIV NCLQPHPGHC FLATSGIDPV
     VRLWSPRPEC ENENGRVVED MEGAAQANQR RMNADPLEVM LLNMGYRISG LSSRGAEGSD
     EEDSSEGQVQ CRSS
//