ID B0S754_DANRE Unreviewed; 2134 AA.
AC B0S754;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 10-MAY-2017, entry version 88.
DE SubName: Full=Small nuclear ribonucleoprotein 200 (U5) {ECO:0000313|Ensembl:ENSDARP00000098660};
GN Name=snrnp200 {ECO:0000313|Ensembl:ENSDARP00000098660,
GN ECO:0000313|ZFIN:ZDB-GENE-081105-64};
GN Synonyms=si:ch211-251j10.5 {ECO:0000313|ZFIN:ZDB-GENE-081105-64};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000098660, ECO:0000313|Proteomes:UP000000437};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000098660, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000098660,
RC ECO:0000313|Proteomes:UP000000437};
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S.,
RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the
RT human genome.";
RL Nature 496:498-503(2013).
RN [2] {ECO:0000313|Ensembl:ENSDARP00000098660}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000098660};
RG Ensembl;
RL Submitted (APR-2013) to UniProtKB.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSDARP00000098660}.
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DR EMBL; BX640472; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CR376723; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001116729.1; NM_001123257.1.
DR UniGene; Dr.32574; -.
DR ProteinModelPortal; B0S754; -.
DR STRING; 7955.ENSDARP00000098660; -.
DR PaxDb; B0S754; -.
DR PeptideAtlas; B0S754; -.
DR PRIDE; B0S754; -.
DR Ensembl; ENSDART00000109885; ENSDARP00000098660; ENSDARG00000077536.
DR GeneID; 799690; -.
DR KEGG; dre:799690; -.
DR CTD; 23020; -.
DR ZFIN; ZDB-GENE-081105-64; snrnp200.
DR eggNOG; KOG0952; Eukaryota.
DR eggNOG; COG1204; LUCA.
DR GeneTree; ENSGT00640000091272; -.
DR HOGENOM; HOG000157749; -.
DR HOVERGEN; HBG051896; -.
DR InParanoid; B0S754; -.
DR KO; K12854; -.
DR OMA; KKMENWW; -.
DR OrthoDB; EOG091G0HE5; -.
DR PhylomeDB; B0S754; -.
DR TreeFam; TF300056; -.
DR Reactome; R-DRE-72163; mRNA Splicing - Major Pathway.
DR Reactome; R-DRE-72165; mRNA Splicing - Minor Pathway.
DR Proteomes; UP000000437; Chromosome 8.
DR Bgee; ENSDARG00000077536; -.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 2.60.40.150; -; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR011991; WHTH_DNA-bd_dom.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 2.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF46785; SSF46785; 2.
DR SUPFAM; SSF52540; SSF52540; 4.
DR SUPFAM; SSF81296; SSF81296; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 2.
PE 1: Evidence at protein level;
KW Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW Proteomics identification {ECO:0000213|PeptideAtlas:B0S754};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT DOMAIN 487 670 Helicase ATP-binding.
FT {ECO:0000259|PROSITE:PS51192}.
FT DOMAIN 681 918 Helicase C-terminal.
FT {ECO:0000259|PROSITE:PS51194}.
FT DOMAIN 1333 1508 Helicase ATP-binding.
FT {ECO:0000259|PROSITE:PS51192}.
FT DOMAIN 1568 1749 Helicase C-terminal.
FT {ECO:0000259|PROSITE:PS51194}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 492 670 ismart:AAA [T]
FT MYHIT 1338 1496 ismart:AAA [T]
FT MYHIT 480 655 ipfam:DEAD [T]
FT MYHIT 979 1282 ipfam:Sec63 [T]
FT MYHIT 1326 1492 ipfam:DEAD [T]
FT MYHIT 1603 1691 ismart:HELICc [T]
FT MYHIT 765 857 ismart:HELICc [T]
FT MYHIT 978 1283 ismart:Sec63 [T]
FT MYHIT 474 687 ismart:DEXDc [T]
FT MYHIT 681 918 iprf:HELICASE_CTER [T]
FT MYHIT 1808 2120 ismart:Sec63 [T]
FT MYHIT 1320 1524 ismart:DEXDc [T]
FT MYHIT 1333 1508 iprf:HELICASE_ATP_BIND_1 [T]
FT MYHIT 1808 2119 ipfam:Sec63 [T]
FT MYHIT 487 670 iprf:HELICASE_ATP_BIND_1 [T]
FT MYHIT 711 855 ipfam:Helicase_C [T]
FT MYHIT 1568 1749 iprf:HELICASE_CTER [T]
SQ SEQUENCE 2134 AA; 243985 MW; 3A87928F0CB7E1C9 CRC64;
MADVTARSLQ YEYKANSNLV LQADRSLIDR TRRDEPTGEV LSLVGKLEGT KMGDRSQRTK
PQMLEERRAK RRKRDEDRHD INKMKGFTLL SEGIDEMVGI VYKPKTKETR ETYEILLSFI
QAALGDQPRD ILCGAADEVL AVLKNDKMRD KERRREVEQL LGPTDDTRYH VLVNLGKKIS
DYGGDKELQN MDDNIDETYG VNVQFESDEE EGDEDQYGEV RDEGSDDSEG EEADESSTLT
ANLGNTGDVM MTKKKDLHPR DIDAFWLQRQ LSRFYNDAIV SQKKADEVLE ILKTASDDRE
CENQLVLLLG FNTFDFIKVL RQHRRMILYC TMLASAQSEA EKEKIINKME ADQDLSKVLY
QLQETEKEDI IREERSRRER MRKSRVDDLE SMDIDHGESV SSRQLLDLED LTFTQGSHFM
ANKRCQLPDG SFRKQRKGYE EVHVPALKPK PFGDEETLVG IEKLPKYAQA GFEGFKSLNR
IQSKLFKTTM ETDENLLVCA PTGAGKTNVA LMAMLREIGK HINMDGTINV ADFKIIYIAP
MRSLVQEMVG SFGKRLASYG IIVSELTGDH QLCKEEINAT QIIVCTPEKW DIITRKGGER
TYTQLVRLII IDEIHLLHDD RGPVLESLIA RTIRNVELTQ EDVRLIGLSA TLPNYEDVAT
CLRVDPSKGL FYFDNSFRPV PLEQTYVGIT EKKAIKRFQI MNEIVYEKIM EHAGKNQVLV
FVHSRKETGK TARAIRDMCL EKDTLGLFLR EGSASTEVLR TEAEQCKNLE LKDLLPYGFA
IHHAGMTRVD RTLVEDLFAD RHIQVLVSTA TLAWGVNLPA HTVIIKGTQV YSPEKGRWTE
LGALDILQML GRAGRPQYDS KGEGILITSH GELQYYLSLL NQQLPIESQM VGKLADMLNA
EIVLGNVQNA KDAVNWLGYT YLYVRMLRNP TLYGVSHDDR SIDPLLERRR MDLVHTAATV
LEKNNLVKYD KRSGSFQVTD LGRIASHFYI THESIMTYNQ LLKPTLSEIE LFRVFSLSSE
FRNITVREEE KLELQKLLER VPIPVKESIE EPSAKINVLL QAYISQLKLE GFALMADMVY
VTQSAGRLMR AIFEIVLSRG WAQLTDKTLN LCKMIDKRMW QSMSPLRQFR KLPEEVIKKI
EKKNFPFERL YDLNHNEIGE LIRMPKMGKT IHKYVHQFPK LDLAVHLQPI TRSTLKVELT
ITPDFQWDDK IHGSSEAFWI LVEDVDSEVV LHHEYFLLKA KYAQDEHLVT FFVPVFEPLP
PQYFIRIASD RWLSCETQLP VSFRHLILPE KYPPPTELLD LQPLPVSALR NGAFESLYQN
FPFFNPIQTQ VFNAVYNSDD NVFVGAPTGS GKTICAEFAI LRMLLHNAEG RCVYITPMEA
LAEQVFLDWH QKFQENLNKK VVLLTGETST DLKLLGKGDI IVSTPDKWDI LSRRWKQRKN
VQNVSLFIID EVHLIGGDNG PVLEVICSRM RYISSQIERP IRIVALSSSL SNAKDVAHWL
GCSTTATFNF HPNVRPVPLE LHIQGFNVSH TQTRLLSMAK PVYHAIMKHS PSKPVLVFVP
SRRQTRLTAI DILTFCAADV VPQRFLHSTE KDLVPFMENL SDVTLKETLS NGVGYLHEGL
SPTERRIVEH LFTSGAIQVV VASRSLCWGT NISAHLVIVM DTQYYNGKIH AYVDYPIYDV
LQMVGKANRP LQDDEGRCVI MCQGSKKDFF KKFLYEPLPV ESHLDHCLHD HFNAEIVTKT
VENKQDAVDY LTWTFLYRRM TQNPNYYNLQ GMSHRHLSDH LSELVENTLQ DLEQSKCISI
EDEMDVAPLN LGMIAAYYYI NYTTIELFSM SLNAKTKVRG LIEIISNAAE YKNIPIRHHE
DTLLRQLAQK VPHKLNNPKF NDPHVKTNLL LQAHLSRMQL SAELQSDTEE ILSKAVRLIQ
ACVDVLSSNG WLSPALAAME LAQMVTQAMW SKDSYLRQLP HFTSELIKRC TDKGVESIFD
IMEMEDEDRT GLLQLSDVQV ADVARFCNRY PNIELSYEVV DKDDIKSGSP VVVQVQLERE
EEVTGPVIAP LFPQKREEGW WVVIGDPKSN SLISIKRLTL QQKAKVKLDF VAPVVGVHNY
TLYFMSDAYM GCDQEYKFST EVKEADSEGD SDSD
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