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DescriptionSubName: Full=Zgc:162183 {ECO:0000313|Ensembl:ENSDARP00000102971}; SubName: Full=Zgc:162183 protein {ECO:0000313|EMBL:AAI39537.1};
MyHits logo
MyHits synonymsA4QNV5_DANRE , A4QNV5 , 21D01A24BC44ABCF
match map segment
ipfam:SAM_1 ipfam:PAP2_C iprf:SAM_DOMAIN ismart:SAM  
Legends: 1, TRANSMEM Helical. {ECO:0000256|SAM:Phobius}; 2, SAM (sterile alpha motif). {ECO:0000259|PROSITE:PS50105}; 3, iprf:SAM_DOMAIN [T].
ID   A4QNV5_DANRE            Unreviewed;       412 AA.
AC   A4QNV5;
DT   15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   15-MAY-2007, sequence version 1.
DT   10-MAY-2017, entry version 72.
DE   SubName: Full=Zgc:162183 {ECO:0000313|Ensembl:ENSDARP00000102971};
DE   SubName: Full=Zgc:162183 protein {ECO:0000313|EMBL:AAI39537.1};
GN   ORFNames=zgc:162183 {ECO:0000313|EMBL:AAI39537.1,
GN   ECO:0000313|Ensembl:ENSDARP00000102971,
GN   ECO:0000313|ZFIN:ZDB-GENE-070410-30};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI39537.1};
RN   [1] {ECO:0000313|EMBL:AAI39537.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Whole {ECO:0000313|EMBL:AAI39537.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000102971}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000102971};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000102971, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000102971,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
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DR   EMBL; CU928227; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC139536; AAI39537.1; -; mRNA.
DR   RefSeq; NP_001082939.1; NM_001089470.1.
DR   UniGene; Dr.86797; -.
DR   STRING; 7955.ENSDARP00000102971; -.
DR   Ensembl; ENSDART00000113936; ENSDARP00000102971; ENSDARG00000074663.
DR   GeneID; 100037314; -.
DR   KEGG; dre:100037314; -.
DR   ZFIN; ZDB-GENE-070410-30; zgc:162183.
DR   eggNOG; KOG3058; Eukaryota.
DR   eggNOG; ENOG410XNSC; LUCA.
DR   GeneTree; ENSGT00390000001630; -.
DR   HOGENOM; HOG000233822; -.
DR   HOVERGEN; HBG048216; -.
DR   TreeFam; TF314547; -.
DR   Proteomes; UP000000437; Chromosome 17.
DR   Bgee; ENSDARG00000074663; -.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0047493; F:ceramide cholinephosphotransferase activity; IBA:GO_Central.
DR   GO; GO:0033188; F:sphingomyelin synthase activity; IBA:GO_Central.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IBA:GO_Central.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed.
DR   InterPro; IPR025749; Sphingomyelin_synth-like_dom.
DR   Pfam; PF14360; PAP2_C; 1.
DR   Pfam; PF00536; SAM_1; 1.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    151    174       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    194    217       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    229    251       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    293    312       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    319    338       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    344    364       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       12     78       SAM (sterile alpha motif).
FT                                {ECO:0000259|PROSITE:PS50105}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT        11     75       ipfam:SAM_1 [T]
FT   MYHIT       289    362       ipfam:PAP2_C [T]
FT   MYHIT        12     78       iprf:SAM_DOMAIN [T]
FT   MYHIT         9     78       ismart:SAM [T]
SQ   SEQUENCE   412 AA;  46868 MW;  21D01A24BC44ABCF CRC64;
     MPSSRCTGVE GWSSKQVAVW LREQGFREYV DLLCSKHRLD GPSLLCLTEK DLRSPPLELK
     VLGDIKRLSL AIRRLQKHYT TLTHSDSSAL SKIDTGGTEQ TLSNGYLERA SIDHQHCNGT
     VATVDGDHSY SNGKRKSHCG RLDPEYWKTA LGALYAMMVC GVTSFVMVLV HERVPDMRTY
     PPLPDIFLDS VPRIPWAFAM AEACAVVLGS MLMLVLLMHR HRSILFRRLC NLTGTVFLLR
     CVTMFVTSLS VPGHHLQCSG KIYGDAWTKV QRALEIWSGL GMSLTGVHTC GDYMFSGHTV
     VLTMLNFFVT EYTPRNWNFI HTMSWVLNLF GIFFILAAHE HYSIDVFIAF YITTRLFLYY
     HTLANTQAYQ HSRRARVWFP LFSFFECNVL GPVPNEYCWP FPTPSFINIL LG
//