ID A4QNV5_DANRE Unreviewed; 412 AA.
AC A4QNV5;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 10-MAY-2017, entry version 72.
DE SubName: Full=Zgc:162183 {ECO:0000313|Ensembl:ENSDARP00000102971};
DE SubName: Full=Zgc:162183 protein {ECO:0000313|EMBL:AAI39537.1};
GN ORFNames=zgc:162183 {ECO:0000313|EMBL:AAI39537.1,
GN ECO:0000313|Ensembl:ENSDARP00000102971,
GN ECO:0000313|ZFIN:ZDB-GENE-070410-30};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI39537.1};
RN [1] {ECO:0000313|EMBL:AAI39537.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole {ECO:0000313|EMBL:AAI39537.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000102971}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000102971};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
RN [3] {ECO:0000313|Ensembl:ENSDARP00000102971, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000102971,
RC ECO:0000313|Proteomes:UP000000437};
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S.,
RA Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the
RT human genome.";
RL Nature 496:498-503(2013).
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DR EMBL; CU928227; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC139536; AAI39537.1; -; mRNA.
DR RefSeq; NP_001082939.1; NM_001089470.1.
DR UniGene; Dr.86797; -.
DR STRING; 7955.ENSDARP00000102971; -.
DR Ensembl; ENSDART00000113936; ENSDARP00000102971; ENSDARG00000074663.
DR GeneID; 100037314; -.
DR KEGG; dre:100037314; -.
DR ZFIN; ZDB-GENE-070410-30; zgc:162183.
DR eggNOG; KOG3058; Eukaryota.
DR eggNOG; ENOG410XNSC; LUCA.
DR GeneTree; ENSGT00390000001630; -.
DR HOGENOM; HOG000233822; -.
DR HOVERGEN; HBG048216; -.
DR TreeFam; TF314547; -.
DR Proteomes; UP000000437; Chromosome 17.
DR Bgee; ENSDARG00000074663; -.
DR GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0047493; F:ceramide cholinephosphotransferase activity; IBA:GO_Central.
DR GO; GO:0033188; F:sphingomyelin synthase activity; IBA:GO_Central.
DR GO; GO:0046513; P:ceramide biosynthetic process; IBA:GO_Central.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed.
DR InterPro; IPR025749; Sphingomyelin_synth-like_dom.
DR Pfam; PF14360; PAP2_C; 1.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SSF47769; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 2: Evidence at transcript level;
KW Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 151 174 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 194 217 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 229 251 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 293 312 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 319 338 Helical. {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 344 364 Helical. {ECO:0000256|SAM:Phobius}.
FT DOMAIN 12 78 SAM (sterile alpha motif).
FT {ECO:0000259|PROSITE:PS50105}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 11 75 ipfam:SAM_1 [T]
FT MYHIT 289 362 ipfam:PAP2_C [T]
FT MYHIT 12 78 iprf:SAM_DOMAIN [T]
FT MYHIT 9 78 ismart:SAM [T]
SQ SEQUENCE 412 AA; 46868 MW; 21D01A24BC44ABCF CRC64;
MPSSRCTGVE GWSSKQVAVW LREQGFREYV DLLCSKHRLD GPSLLCLTEK DLRSPPLELK
VLGDIKRLSL AIRRLQKHYT TLTHSDSSAL SKIDTGGTEQ TLSNGYLERA SIDHQHCNGT
VATVDGDHSY SNGKRKSHCG RLDPEYWKTA LGALYAMMVC GVTSFVMVLV HERVPDMRTY
PPLPDIFLDS VPRIPWAFAM AEACAVVLGS MLMLVLLMHR HRSILFRRLC NLTGTVFLLR
CVTMFVTSLS VPGHHLQCSG KIYGDAWTKV QRALEIWSGL GMSLTGVHTC GDYMFSGHTV
VLTMLNFFVT EYTPRNWNFI HTMSWVLNLF GIFFILAAHE HYSIDVFIAF YITTRLFLYY
HTLANTQAYQ HSRRARVWFP LFSFFECNVL GPVPNEYCWP FPTPSFINIL LG
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