Entry euk:A2BIA5_DANRE

ID   A2BIA5_DANRE            Unreviewed;       177 AA.
AC   A2BIA5;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   10-MAY-2017, entry version 73.
DE   SubName: Full=Biogenesis of lysosomal organelles complex-1, subunit 2 {ECO:0000313|Ensembl:ENSDARP00000110597};
GN   Name=bloc1s2 {ECO:0000313|Ensembl:ENSDARP00000110597,
GN   ECO:0000313|ZFIN:ZDB-GENE-050809-129};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000110597, ECO:0000313|Proteomes:UP000000437};
RN   [1] {ECO:0000313|Ensembl:ENSDARP00000121837}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000121837};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000110597, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000110597,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000110597}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000110597};
RG   Ensembl;
RL   Submitted (AUG-2013) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSDARP00000110597}.
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DR   EMBL; BX897740; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001028273.2; NM_001033101.2.
DR   RefSeq; XP_009292839.1; XM_009294564.2.
DR   UniGene; Dr.48553; -.
DR   STRING; 7955.ENSDARP00000110597; -.
DR   Ensembl; ENSDART00000127975; ENSDARP00000110597; ENSDARG00000046081.
DR   Ensembl; ENSDART00000144551; ENSDARP00000121837; ENSDARG00000046081.
DR   GeneID; 606665; -.
DR   KEGG; dre:606665; -.
DR   CTD; 282991; -.
DR   ZFIN; ZDB-GENE-050809-129; bloc1s2.
DR   eggNOG; KOG4559; Eukaryota.
DR   eggNOG; ENOG4111XFP; LUCA.
DR   GeneTree; ENSGT00390000005889; -.
DR   HOGENOM; HOG000111279; -.
DR   HOVERGEN; HBG079627; -.
DR   KO; K16750; -.
DR   OMA; QQLAPMM; -.
DR   OrthoDB; EOG091G0V5M; -.
DR   TreeFam; TF313861; -.
DR   Proteomes; UP000000437; Chromosome 20.
DR   Bgee; ENSDARG00000046081; -.
DR   GO; GO:1905457; P:negative regulation of lymphoid progenitor cell differentiation; IMP:ZFIN.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IMP:ZFIN.
DR   GO; GO:1902038; P:positive regulation of hematopoietic stem cell differentiation; IMP:ZFIN.
DR   GO; GO:1905455; P:positive regulation of myeloid progenitor cell differentiation; IMP:ZFIN.
DR   InterPro; IPR019269; BLOC1_su2.
DR   Pfam; PF10046; BLOC1_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT        78    172       ipfam:BLOC1_2 [T]
SQ   SEQUENCE   177 AA;  19892 MW;  A093D802AA6A880F CRC64;
     MAATGDEAAA MDSISKAPAP PTELNLTAEP ENSREATTSD TTENQKPKRP SNNNDGGVET
     AEEATEPAEP DINELCRDMF DKMSVFLQGE LTATCEDYKL LENMNKLTSL KYMEMKDISI
     NISRNLQDLN QKYASLQPYL DQINQIEEQV TALEQAAYKL DTYSKKLEAK FKKLEKR
//