ID A2ATL1_MOUSE Unreviewed; 767 AA.
AC A2ATL1;
DT 20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 20-FEB-2007, sequence version 1.
DT 10-MAY-2017, entry version 70.
DE SubName: Full=Family with sequence similarity 171, member A1 {ECO:0000313|Ensembl:ENSMUSP00000072724};
DE SubName: Full=MCG17280 {ECO:0000313|EMBL:EDL07920.1};
GN Name=Fam171a1 {ECO:0000313|Ensembl:ENSMUSP00000072724,
GN ECO:0000313|MGI:MGI:2442917};
GN ORFNames=mCG_17280 {ECO:0000313|EMBL:EDL07920.1};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC Muroidea; Muridae; Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000072724, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|EMBL:EDL07920.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Mixed {ECO:0000313|EMBL:EDL07920.1};
RX PubMed=12040188; DOI=10.1126/science.1069193;
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R.,
RA Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A.,
RA Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.,
RA Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K.,
RA Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J.,
RA Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R.,
RA Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H.,
RA Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A.,
RA Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A.,
RA Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C.,
RA Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C.,
RA Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B.,
RA Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E.,
RA Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R.,
RA Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C.,
RA Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L.,
RA Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S.,
RA Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L.,
RA Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R.,
RA Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R.,
RA Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J.,
RA Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L.,
RA Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C.,
RA Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A.,
RA Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H.,
RA Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L.,
RA Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M.,
RA Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K.,
RA Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S.,
RA Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J.,
RA Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G.,
RA Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.;
RT "A comparison of whole-genome shotgun-derived mouse chromosome 16 and
RT the human genome.";
RL Science 296:1661-1671(2002).
RN [2] {ECO:0000313|EMBL:EDL07920.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Mixed {ECO:0000313|EMBL:EDL07920.1};
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000072724, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000072724,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of
RT the mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [4] {ECO:0000213|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and
RT expression.";
RL Cell 143:1174-1189(2010).
RN [5] {ECO:0000313|Ensembl:ENSMUSP00000072724}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000072724};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
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DR EMBL; AL928883; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH466542; EDL07920.1; -; Genomic_DNA.
DR RefSeq; NP_001297363.1; NM_001310434.1.
DR UniGene; Mm.23044; -.
DR STRING; 10090.ENSMUSP00000110751; -.
DR Ensembl; ENSMUST00000072955; ENSMUSP00000072724; ENSMUSG00000050530.
DR GeneID; 269233; -.
DR KEGG; mmu:269233; -.
DR UCSC; uc008idm.1; mouse.
DR CTD; 221061; -.
DR MGI; MGI:2442917; Fam171a1.
DR eggNOG; ENOG410IKM3; Eukaryota.
DR eggNOG; ENOG410ZV9V; LUCA.
DR GeneTree; ENSGT00530000063318; -.
DR HOGENOM; HOG000231925; -.
DR HOVERGEN; HBG057508; -.
DR ChiTaRS; Fam171a1; mouse.
DR Proteomes; UP000000589; Chromosome 2.
DR Bgee; ENSMUSG00000050530; -.
DR GO; GO:0070062; C:extracellular exosome; ISO:MGI.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018890; Uncharacterised_FAM171.
DR Pfam; PF10577; UPF0560; 1.
PE 1: Evidence at protein level;
KW Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0000213|MaxQB:A2ATL1,
KW ECO:0000213|PeptideAtlas:A2ATL1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 179 202 Helical. {ECO:0000256|SAM:Phobius}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 1 765 ipfam:UPF0560 [T]
SQ SEQUENCE 767 AA; 84794 MW; B42B64CDFB521C65 CRC64;
MVYEDVVQIV SGFQGARPQP RVHFQRRALR LPENTSYSDL TAFLTAASSP SEVDSFPYLR
GLDGNGTGNS TRYDLTPVTA VSVHLLSGNG MPVLVDGPIY VTVPLATQSS LRHNAYVAAW
RFDQKLGTWL KSGLGLVHQE GSQLTWTYIA PQLGYWVAAM SPPIPGPVMT QDITTYHTVF
LLAILGGMAF ILLVLLCLLL YYCRRKCLKP RQHHRKLQLP PALESSKRDQ ATSMSHINLL
FSRRASDYPG PLSVSSHSRP EAPGTKELMG GVHLEMMSPK GEGDLHTPML KLSYSTSQEF
SSREELLSHK EEDKSQTSFD NLTPSGTLGK DYHKSVEIFP LKARKSMEKE DYEAPGNDDY
RGSYNTVLSQ SLFEKQDQEG LASAGSKLTI QEHMYHVPLS PEKEQLLDRR PTECMMSRSV
DHLERPTSFP RPGQLICCSS VDQVNDSVYR KVLPALVIPA HYMKLPGDHS YVSQPLVVPA
DQQLEIGRLQ AELSNPHAGI FPHPSSQIQG QPLSSQAISQ QHLQEAGARE WSSQSASMSE
SLSIPASLND AALAQMNSEV QLLTEKALME LGGGKPLPHP RAWFVSLDGR SNAHVRHSYI
DLQRAGRNGS NDASLDSGVD MNEPKSARKG RGDPLSLQQS HTPLQEHQQK DPRAPDSTAC
TQLLYLEDMD PSGSECAATV CTPEDSALRC LLEGSGRRSG GQLPSLQEET TKRTSDVPLE
PLASPNQRRS ANDEDEDDDD DDDDQGEDKK SPWQKREERP LMAFNIK
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