Entry euk:A2AK62_MOUSE

ID   A2AK62_MOUSE            Unreviewed;       313 AA.
AC   A2AK62;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   10-MAY-2017, entry version 88.
DE   SubName: Full=Olfactory receptor 1066 {ECO:0000313|Ensembl:ENSMUSP00000097470};
GN   Name=Olfr1066 {ECO:0000313|Ensembl:ENSMUSP00000097470,
GN   ECO:0000313|MGI:MGI:3030900};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000097470, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000097470, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000097470,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000097470}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000097470};
RG   Ensembl;
RL   Submitted (DEC-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|SAAS:SAAS00521146}; Multi-pass membrane protein
CC       {ECO:0000256|SAAS:SAAS00521146}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|SAAS:SAAS00591716}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSMUSP00000097470}.
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DR   EMBL; AL772265; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001011735.2; NM_001011735.2.
DR   UniGene; Mm.377281; -.
DR   ProteinModelPortal; A2AK62; -.
DR   STRING; 10090.ENSMUSP00000097470; -.
DR   PaxDb; A2AK62; -.
DR   Ensembl; ENSMUST00000099885; ENSMUSP00000097470; ENSMUSG00000075181.
DR   GeneID; 257880; -.
DR   KEGG; mmu:257880; -.
DR   UCSC; uc008kmk.1; mouse.
DR   CTD; 257880; -.
DR   MGI; MGI:3030900; Olfr1066.
DR   GeneTree; ENSGT00810000125371; -.
DR   HOGENOM; HOG000041364; -.
DR   InParanoid; A2AK62; -.
DR   OMA; SQKVCWI; -.
DR   OrthoDB; EOG091G0AZH; -.
DR   PhylomeDB; A2AK62; -.
DR   TreeFam; TF352749; -.
DR   Reactome; R-MMU-381753; Olfactory Signaling Pathway.
DR   Proteomes; UP000000589; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR   GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISA:MGI.
DR   GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|SAAS:SAAS00521172};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   G-protein coupled receptor {ECO:0000256|SAAS:SAAS00529918};
KW   Membrane {ECO:0000256|SAAS:SAAS00520911,
KW   ECO:0000256|SAAS:SAAS00521172, ECO:0000256|SAM:Phobius};
KW   Olfaction {ECO:0000256|SAAS:SAAS00521184};
KW   Receptor {ECO:0000256|SAAS:SAAS00529918};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Sensory transduction {ECO:0000256|SAAS:SAAS00521184};
KW   Transducer {ECO:0000256|SAAS:SAAS00529918};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00520911,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00520911,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     27     51       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    103    126       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    132    151       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    197    225       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    237    261       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       41    290       G_PROTEIN_RECEP_F1_2.
FT                                {ECO:0000259|PROSITE:PS50262}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT        41    290       iprf:G_PROTEIN_RECEP_F1_2 [T]
SQ   SEQUENCE   313 AA;  35368 MW;  C80B14CACB6B388D CRC64;
     MEKYNLTMVT EFILVGITYH PEFQVPLFGL FLIIYLTSLF GNLGMIILTM VDSGLQTPMY
     FFLRHLATTD LGYSTAVGPK MLRNFLVDQN TISFNACDIQ SSFFSMFIVC EFFILSALSY
     DCYVAICKPL LYTVIMSQKV CWILVTIPYL YSIIVSLIIN IKIFTLSFCG YNVISHFYCD
     ALPLLTLACS NTHEIEAIIL IFSAFNLLSS LLIVIGSYLL ILMAILRINS TEGKWKAFST
     CGSHLTVVIV FYGTLICMYL QPTSTHSIDT GKGTSIFYTQ VIPMLNPLIY SLRNKDVTDV
     LKKTKEKVYN LVS
//