Entry euk:A0A0R4IRT8_DANRE

ID   A0A0R4IRT8_DANRE        Unreviewed;       920 AA.
AC   A0A0R4IRT8;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   10-MAY-2017, entry version 9.
DE   SubName: Full=Zgc:153345 {ECO:0000313|Ensembl:ENSDARP00000138086};
GN   ORFNames=zgc:153345 {ECO:0000313|Ensembl:ENSDARP00000138086,
GN   ECO:0000313|ZFIN:ZDB-GENE-061103-487};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000138086, ECO:0000313|Proteomes:UP000000437};
RN   [1] {ECO:0000313|Ensembl:ENSDARP00000138086, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000138086,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000138086}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000138086};
RG   Ensembl;
RL   Submitted (NOV-2015) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSDARP00000138086}.
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DR   EMBL; BX088525; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSDART00000163458; ENSDARP00000138086; ENSDARG00000055622.
DR   ZFIN; ZDB-GENE-061103-487; zgc:153345.
DR   GeneTree; ENSGT00760000119123; -.
DR   Reactome; R-DRE-194840; Rho GTPase cycle.
DR   Proteomes; UP000000437; Chromosome 10.
DR   ExpressionAtlas; A0A0R4IRT8; baseline.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; SSF48350; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT   DOMAIN       55    256       Rho-GAP. {ECO:0000259|PROSITE:PS50238}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT        55    256       iprf:RHOGAP [T]
FT   MYHIT        70    253       ismart:RhoGAP [T]
FT   MYHIT        73    226       ipfam:RhoGAP [T]
SQ   SEQUENCE   920 AA;  101743 MW;  A28CC9CD0ADD17E2 CRC64;
     MGGLTEERVR VVAIIQALKA VGIRVKNWKN FLNGNSNCEQ TLCQENASQR FAFGRDLHLL
     PQHDLPDNGG TVPRFLVEAC VFLSQHLNTE GLFRKTGSLT RIRALRADLE QGKPVFLPPH
     SSLLQASDVA SLIKQFLREL SSPLIPTDLQ IPLIQAQGLE MTHDQEGARN RTTLLITALF
     PSSNACALRY LCTFLRQVAD RCSENRMDAS SLAVVIAPNL LQCPTQPNKL TLDTEKHLDQ
     QTSVIKSLIL NADRIGVVPS CLLEPSKSTG GIGTPSPVGG TMFSKRTGLS VYRSLRRQRR
     RSVGEIFVDA FSKLKPCRTP TEPAIVLGVA SETLLLKSPT PQSPVTVKRK AAEESLPELE
     GSARKRRSLH DLREDTTTTI TQESVDSRSP LEDNCSNEDP TPTTTKKRSH TRDQRKSLKP
     PGQEEKVNRR RKSLRFFTVS SGSNSSNLSV SPADKVLENG LEEQPNTKSG APFTNAELSS
     NIPFILIDGP EGVVVGSEVD DDPDLLNCSF AESPNDCPNT RSEVSCIQGQ DSEVPCDDEC
     WTVLESEKFE PLAECELIQP VTQHEGFQVN AGTEVKNEPE VKQLEEQPRK ESKKVKNSFK
     NRSRPRRSIS LPEVTLESCT HALADLEKEV VGAEPEMEDS VWPMFESLTL SNEHDNVTAE
     KKVGSKEAQE TKGSVKTLKN YKQDKMADST LGFKRPHQRL SMAERLRGFS ALTLLLRTSR
     AAPQFRDKPQ ESLQKAAARL KRQGARRFGR SISHDGVPER EAEQDPVGSP PANQAYLGLC
     DASPDSGVES VDHEPINDLI SQDICKGPQN SPKAQPTNEV DVDSLISFEN PNQDLILSAS
     DKTECEFQCK KTNQDVEELD LHKLLDQKCQ IGGQEEDDCH DSDVLTEVLS PDIASPMFLQ
     EMVPLNLFGD VDDLRKDQIS
//