Entry euk:A0A0J9YW98_HUMAN

ID   A0A0J9YW98_HUMAN        Unreviewed;       536 AA.
AC   A0A0J9YW98;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   10-MAY-2017, entry version 11.
DE   SubName: Full=HCG31704 {ECO:0000313|EMBL:EAW82216.1};
DE   SubName: Full=Zinc finger protein 623 {ECO:0000313|Ensembl:ENSP00000487869};
GN   Name=ZNF623 {ECO:0000313|Ensembl:ENSP00000487869};
GN   ORFNames=hCG_31704 {ECO:0000313|EMBL:EAW82216.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000487869, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|EMBL:EAW82216.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=11181995; DOI=10.1126/science.1058040;
RA   Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G.,
RA   Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D.,
RA   Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q.,
RA   Kodira C.D., Zheng X.H., Chen L., Skupski M., Subramanian G.,
RA   Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S.,
RA   Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J.,
RA   Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R.,
RA   Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A.,
RA   Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K.,
RA   Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V.,
RA   Brandon R., Cargill M., Chandramouliswaran I., Charlab R.,
RA   Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K.,
RA   Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z.,
RA   Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A.,
RA   Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V.,
RA   Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B.,
RA   Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J.,
RA   Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C.,
RA   Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L.,
RA   Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S.,
RA   Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A.,
RA   Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D.,
RA   Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L.,
RA   Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N.,
RA   Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S.,
RA   Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F.,
RA   Kline L., Koduru S., Love A., Mann F., May D., McCawley S.,
RA   McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K.,
RA   Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M.,
RA   Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C.,
RA   Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N.,
RA   Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M.,
RA   Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F.,
RA   Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A.,
RA   Mi H., Lazareva B., Hatton T., Narechania A., Diemer K.,
RA   Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R.,
RA   Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J.,
RA   Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H.,
RA   Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D.,
RA   Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A.,
RA   Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S.,
RA   Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L.,
RA   Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W.,
RA   McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M.,
RA   Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J.,
RA   Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E.,
RA   Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.;
RT   "The sequence of the human genome.";
RL   Science 291:1304-1351(2001).
RN   [2] {ECO:0000313|Ensembl:ENSP00000487869}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [3] {ECO:0000313|EMBL:EAW82216.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L.,
RA   Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA   Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA   Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA   Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA   Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA   Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA   Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S.,
RA   Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A.,
RA   Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X.,
RA   Allen N.R., Anderson S., Asakawa T., Blechschmidt K., Bloom T.,
RA   Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K.,
RA   DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G.,
RA   Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B.,
RA   Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C.,
RA   O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K.,
RA   Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R.,
RA   Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K.,
RA   Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q.,
RA   Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N.,
RA   Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [5] {ECO:0000313|Ensembl:ENSP00000487869}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2015) to UniProtKB.
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DR   EMBL; AC243411; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471162; EAW82216.1; -; Genomic_DNA.
DR   RefSeq; NP_055604.3; NM_014789.3.
DR   UniGene; Hs.43133; -.
DR   UniGene; Hs.694018; -.
DR   UniGene; Hs.745418; -.
DR   Ensembl; ENST00000633071; ENSP00000487869; ENSG00000276340.
DR   GeneID; 9831; -.
DR   KEGG; hsa:9831; -.
DR   CTD; 9831; -.
DR   HGNC; HGNC:29084; ZNF623.
DR   KO; K09228; -.
DR   OMA; HTEVKQY; -.
DR   GenomeRNAi; 9831; -.
DR   Proteomes; UP000005640; Chromosome 8.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   SMART; SM00355; ZnF_C2H2; 13.
DR   SUPFAM; SSF57667; SSF57667; 7.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 13.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:A0A0J9YW98,
KW   ECO:0000213|MaxQB:A0A0J9YW98, ECO:0000213|PeptideAtlas:A0A0J9YW98};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN      123    150       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      151    178       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      179    206       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      207    234       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      235    262       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      263    290       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      291    318       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      319    346       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      347    374       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      375    402       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      403    430       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      431    458       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT   DOMAIN      459    486       C2H2-type. {ECO:0000259|PROSITE:PS50157}.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT       293    313       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       375    402       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       291    313       ismart:ZnF_C2H2 [T]
FT   MYHIT       263    285       ismart:ZnF_C2H2 [T]
FT   MYHIT       347    374       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       321    341       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       123    150       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       347    369       ismart:ZnF_C2H2 [T]
FT   MYHIT       431    458       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       403    430       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       235    262       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       431    453       ismart:ZnF_C2H2 [T]
FT   MYHIT       433    453       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       123    145       ismart:ZnF_C2H2 [T]
FT   MYHIT       319    346       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       349    369       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       181    201       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       377    397       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       209    229       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       265    285       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       179    201       ismart:ZnF_C2H2 [T]
FT   MYHIT       291    318       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       235    257       ismart:ZnF_C2H2 [T]
FT   MYHIT       459    481       ismart:ZnF_C2H2 [T]
FT   MYHIT       405    425       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       403    425       ismart:ZnF_C2H2 [T]
FT   MYHIT       207    229       ismart:ZnF_C2H2 [T]
FT   MYHIT       459    486       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       319    341       ismart:ZnF_C2H2 [T]
FT   MYHIT       153    173       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       125    145       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       375    397       ismart:ZnF_C2H2 [T]
FT   MYHIT       151    173       ismart:ZnF_C2H2 [T]
FT   MYHIT       237    257       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       263    290       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       207    234       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       151    178       iprf:ZINC_FINGER_C2H2_2 [T]
FT   MYHIT       461    481       ipat:ZINC_FINGER_C2H2_1 [T]
FT   MYHIT       179    206       iprf:ZINC_FINGER_C2H2_2 [T]
SQ   SEQUENCE   536 AA;  61393 MW;  714619E8EE7D6B0E CRC64;
     MILLSFVSDS NVGTGEKKVT EAWISEDENS HRTTSDRLTV MELPSPESEE VHEPRLGELL
     GNPEGQSLGS SPSQDRGCKQ VTVTHWKIQT GETAQVCTKS GRNHILNSDL LLLQRELIEG
     EANPCDICGK TFTFNSDLVR HRISHAGEKP YTCDQCGKGF GQSSHLMEHQ RIHTGERLYV
     CNVCGKDFIH YSGLIEHQRV HSGEKPFKCA QCGKAFCHSS DLIRHQRVHT RERPFECKEC
     GKGFSQSSLL IRHQRIHTGE RPYECNECGK SFIRSSSLIR HYQIHTEVKQ YECKECGKAF
     RHRSDLIEHQ RIHTGERPFE CNECGKAFIR SSKLIQHQRI HTGERPYVCN ECGKRFSQTS
     NFTQHQRIHT GEKLYECNEC GKAFFLSSYL IRHQKIHTGE RVYECKECGK AFLQKAHLTE
     HQKIHSGDRP FECKDCGKAF IQSSKLLLHQ IIHTGEKPYV CSYCGKGFIQ RSNFLQHQKI
     HTEEKLYECS QYGRDFNSTT NVKNNQRVHQ EGLSLSKAPI HLGERSVDKG EHTGNL
//