ID A0A0C4DG37_HUMAN Unreviewed; 363 AA.
AC A0A0C4DG37;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 10-MAY-2017, entry version 17.
DE SubName: Full=Zinc finger protein 439 {ECO:0000313|Ensembl:ENSP00000395632};
GN Name=ZNF439 {ECO:0000313|Ensembl:ENSP00000395632};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000395632, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000395632, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000395632}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2015) to UniProtKB.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSP00000395632}.
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DR EMBL; AC008543; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC008770; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC020951; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001335653.1; NM_001348724.1.
DR RefSeq; NP_001335654.1; NM_001348725.1.
DR UniGene; Hs.528731; -.
DR ProteinModelPortal; A0A0C4DG37; -.
DR STRING; 9606.ENSP00000305077; -.
DR MaxQB; A0A0C4DG37; -.
DR PaxDb; A0A0C4DG37; -.
DR PeptideAtlas; A0A0C4DG37; -.
DR Ensembl; ENST00000455282; ENSP00000395632; ENSG00000171291.
DR GeneID; 90594; -.
DR HGNC; HGNC:20873; ZNF439.
DR OpenTargets; ENSG00000171291; -.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; COG5048; LUCA.
DR GeneTree; ENSGT00760000119089; -.
DR Proteomes; UP000005640; Chromosome 19.
DR ExpressionAtlas; A0A0C4DG37; baseline and differential.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR SMART; SM00355; ZnF_C2H2; 11.
DR SUPFAM; SSF57667; SSF57667; 6.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 11.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 11.
PE 4: Predicted;
KW Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 50 77 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 78 105 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 106 133 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 134 161 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 162 189 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 190 217 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 218 245 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 246 273 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 274 301 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 302 329 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 330 354 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
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CC The following FT lines are automated annotations from the MyHits database.
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FT MYHIT 218 245 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 220 240 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 52 72 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 108 128 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 162 184 ismart:ZnF_C2H2 [T]
FT MYHIT 248 268 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 276 296 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 136 156 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 332 354 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 246 268 ismart:ZnF_C2H2 [T]
FT MYHIT 190 217 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 274 296 ismart:ZnF_C2H2 [T]
FT MYHIT 78 105 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 302 324 ismart:ZnF_C2H2 [T]
FT MYHIT 190 212 ismart:ZnF_C2H2 [T]
FT MYHIT 274 301 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 304 324 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 80 100 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 246 273 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 162 189 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 106 128 ismart:ZnF_C2H2 [T]
FT MYHIT 134 161 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 330 354 ismart:ZnF_C2H2 [T]
FT MYHIT 192 212 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 78 100 ismart:ZnF_C2H2 [T]
FT MYHIT 106 133 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 134 156 ismart:ZnF_C2H2 [T]
FT MYHIT 50 72 ismart:ZnF_C2H2 [T]
FT MYHIT 302 329 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 218 240 ismart:ZnF_C2H2 [T]
FT MYHIT 50 77 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 330 354 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 164 184 ipat:ZINC_FINGER_C2H2_1 [T]
SQ SEQUENCE 363 AA; 42585 MW; 300D5C47E02DEC70 CRC64;
MNIRGDTGHK ACECQEYGPK PWKSQQPKKA FRYHPSLRTQ ERDHTGKKPY ACKECGKNII
YHSSIQRHMV VHSGDGPYKC KFCGKAFHCL SLYLIHERTH TGEKPYECKQ CGKSFSYSAT
HRIHERTHIG EKPYECQECG KAFHSPRSCH RHERSHMGEK AYQCKECGKA FMCPRYVRRH
ERTHSRKKLY ECKQCGKALS SLTSFQTHIR MHSGERPYEC KTCGKGFYSA KSFQRHEKTH
SGEKPYKCKQ CGKAFTRSGS FRYHERTHTG EKPYECKQCG KAFRSAPNLQ LHGRTHTGEK
PYQCKECGKA FRSASQLRIH RRIHTGEKPY ECKKCGKAFR YVQNFRFHER TQTHKNALWR
KTL
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