ID A0A087WTB1_HUMAN Unreviewed; 417 AA.
AC A0A087WTB1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 10-MAY-2017, entry version 16.
DE SubName: Full=Zinc finger protein 772 {ECO:0000313|Ensembl:ENSP00000477730};
GN Name=ZNF772 {ECO:0000313|Ensembl:ENSP00000477730};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000477730, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000477730, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000477730}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2014) to UniProtKB.
CC -!- CAUTION: The sequence shown here is derived from an Ensembl
CC automatic analysis pipeline and should be considered as
CC preliminary data. {ECO:0000313|Ensembl:ENSP00000477730}.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AC003005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC004076; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR ProteinModelPortal; A0A087WTB1; -.
DR PeptideAtlas; A0A087WTB1; -.
DR Ensembl; ENST00000610548; ENSP00000477730; ENSG00000197128.
DR UCSC; uc061dkl.1; human.
DR HGNC; HGNC:33106; ZNF772.
DR OpenTargets; ENSG00000197128; -.
DR GeneTree; ENSGT00760000119107; -.
DR Proteomes; UP000005640; Chromosome 19.
DR ExpressionAtlas; A0A087WTB1; baseline and differential.
DR GO; GO:0005622; C:intracellular; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF01352; KRAB; 1.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SUPFAM; SSF109640; SSF109640; 1.
DR SUPFAM; SSF57667; SSF57667; 4.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE 4: Predicted;
KW Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW Metal-binding {ECO:0000256|SAAS:SAAS00780264};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Repeat {ECO:0000256|SAAS:SAAS00780289};
KW Zinc {ECO:0000256|SAAS:SAAS00780264};
KW Zinc-finger {ECO:0000256|SAAS:SAAS00780264}.
FT DOMAIN 14 85 KRAB. {ECO:0000259|PROSITE:PS50805}.
FT DOMAIN 194 221 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 222 249 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 250 277 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 278 305 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 306 333 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 334 361 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 362 389 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
FT DOMAIN 390 417 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 196 216 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 222 244 ismart:ZnF_C2H2 [T]
FT MYHIT 194 216 ismart:ZnF_C2H2 [T]
FT MYHIT 250 272 ismart:ZnF_C2H2 [T]
FT MYHIT 364 384 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 306 328 ismart:ZnF_C2H2 [T]
FT MYHIT 308 328 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 250 277 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 280 300 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 278 305 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 334 356 ismart:ZnF_C2H2 [T]
FT MYHIT 362 384 ismart:ZnF_C2H2 [T]
FT MYHIT 14 85 iprf:KRAB [T]
FT MYHIT 306 333 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 390 412 ismart:ZnF_C2H2 [T]
FT MYHIT 14 54 ipfam:KRAB [T]
FT MYHIT 278 300 ismart:ZnF_C2H2 [T]
FT MYHIT 390 417 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 194 221 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 252 272 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 362 389 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 334 361 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 14 74 ismart:KRAB [T]
FT MYHIT 392 412 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 222 249 iprf:ZINC_FINGER_C2H2_2 [T]
FT MYHIT 224 244 ipat:ZINC_FINGER_C2H2_1 [T]
FT MYHIT 336 356 ipat:ZINC_FINGER_C2H2_1 [T]
SQ SEQUENCE 417 AA; 47700 MW; 9ECCF8021C1296B9 CRC64;
MNSEVIVDPI QGQVNFEDVF VYFSQEEWVL LDEAQRLLYR DVMLENFALM ASLGHTSFMS
HIVASLVMGS EPWVPDWVDM TLAVATETPG GSCWHGMEDE EIPFEQSFSI GIANLHQHQK
QHSGEKPFRS DKSRPFLLNN CAVQSMEMSF VTGEACKDFL ASSSIFEHHA PHNEWKPHSN
TKCEEASHCG KRHYKCSECG KTFSRKDSLV QHQRVHTGER PYECGECGKT FSRKPILAQH
QRIHTGEMPY ECGICGKVFN HSSNLIVHQR VHTGARPYKC SECGKAYSHK STLVQHESIH
TGERPYECSE CGKYFGHKYR LIKHWSVHTG ARPYECIACG KFFSQSSDLI AHQRVHNGEK
PYVCSECGKA FSHKHVLVQH HRIHTGERPY KCSECGKAFR QRASLIRHWK IHTGERP
//
|
