Entry ecoli:YJCE_ECOLI

ID   YJCE_ECOLI              Reviewed;         549 AA.
AC   P32703; Q2M6N9;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   03-NOV-2009, entry version 71.
DE   RecName: Full=Uncharacterized Na(+)/H(+) exchanger yjcE;
GN   Name=yjcE; OrderedLocusNames=b4065, JW4026;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   MEDLINE=94089392; PubMed=8265357; DOI=10.1093/nar/21.23.5408;
RA   Blattner F.R., Burland V.D., Plunkett G. III, Sofia H.J.,
RA   Daniels D.L.;
RT   "Analysis of the Escherichia coli genome. IV. DNA sequence of the
RT   region from 89.2 to 92.8 minutes.";
RL   Nucleic Acids Res. 21:5408-5417(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   MEDLINE=97426617; PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J.,
RA   Mau B., Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1474(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains
RT   MG1655 and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein (Potential).
CC   -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 1
CC       (CPA1) transporter (TC 2.A.36) family.
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DR   EMBL; U00006; AAC43159.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC77035.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE78067.1; -; Genomic_DNA.
DR   PIR; H65214; H65214.
DR   RefSeq; AP_004566.1; -.
DR   RefSeq; NP_418489.1; -.
DR   STRING; P32703; -.
DR   TCDB; 2.A.36.3.1; monovalent cation:proton antiporter-1 (CPA1) family.
DR   GeneID; 948577; -.
DR   GenomeReviews; AP009048_GR; JW4026.
DR   GenomeReviews; U00096_GR; b4065.
DR   KEGG; ecj:JW4026; -.
DR   KEGG; eco:b4065; -.
DR   EchoBASE; EB1884; -.
DR   EcoGene; EG11940; yjcE.
DR   HOGENOM; P32703; -.
DR   OMA; PAVVRWA; -.
DR   BioCyc; EcoCyc:YJCE-MON; -.
DR   Genevestigator; P32703; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031402; F:sodium ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0015299; F:solute:hydrogen antiporter activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR018422; Cation/H_exchanger_cons-reg.
DR   InterPro; IPR004705; Na/H_exchanger_yjcE-like_bac.
DR   PANTHER; PTHR10110; Cation/H_exchanger_cons-reg; 1.
DR   PANTHER; PTHR10110:SF1; NaHantiport_bac; 1.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
DR   TIGRFAMs; TIGR00831; a_cpa1; 1.
PE   3: Inferred from homology;
KW   Antiport; Cell inner membrane; Cell membrane; Complete proteome;
KW   Ion transport; Membrane; Sodium; Sodium transport; Transmembrane;
KW   Transport.
FT   CHAIN         1    549       Uncharacterized Na(+)/H(+) exchanger
FT                                yjcE.
FT                                /FTId=PRO_0000052399.
FT   TRANSMEM      1     21       Potential.
FT   TRANSMEM     28     48       Potential.
FT   TRANSMEM     50     70       Potential.
FT   TRANSMEM     85    105       Potential.
FT   TRANSMEM    106    126       Potential.
FT   TRANSMEM    165    185       Potential.
FT   TRANSMEM    187    207       Potential.
FT   TRANSMEM    222    242       Potential.
FT   TRANSMEM    278    298       Potential.
FT   TRANSMEM    310    330       Potential.
FT   TRANSMEM    361    381       Potential.
FT   TRANSMEM    398    418       Potential.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT         7    421       ipfam:Na_H_Exchanger [T]
SQ   SEQUENCE   549 AA;  60523 MW;  6F317CF098117DC3 CRC64;
     MEIFFTILIM TLVVSLSGVV TRVMPFQIPL PLMQIAIGAL LAWPTFGLHV EFDPELFLVL
     FIPPLLFADG WKTPTREFLE HGREIFGLAL ALVVVTVVGI GFLIYWVVPG IPLIPAFALA
     AVLSPTDAVA LSGIVGEGRI PKKIMGILQG EALMNDASGL VSLKFAVAVA MGTMIFTVGG
     ATVEFMKVAI GGILAGFVVS WLYGRSLRFL SRWGGDEPAT QIVLLFLLPF ASYLIAEHIG
     VSGILAAVAA GMTITRSGVM RRAPLAMRLR ANSTWAMLEF VFNGMVFLLL GLQLPGILET
     SLMAAEIDPN VEIWMLFTNI ILIYAALMLV RFGWLWTMKK FSNRFLKKKP MEFGSWTTRE
     ILIASFAGVR GAITLAGVLS IPLLLPDGNV FPARYELVFL AAGVILFSLF VGVVMLPILL
     QHIEVADHSQ QLKEERIARA ATAEVAIVAI QKMEERLAAD TEENIDNQLL TEVSSRVIGN
     LRRRADGRND VESSVQEENL ERRFRLAALR SERAELYHLR ATREISNETL QKLLHDLDLL
     EALLIEENQ
//