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DescriptionRecName: Full=UPF0053 inner membrane protein yfjD;
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MyHits synonymsYFJD_ECOLI , P37908 , P76600 , P76601 , P77009 , Q6BF70 , 38456865EDBCB151
match map segment
ipfam:DUF21 ismart:CorC_HlyC ipfam:CBS iprf:CBS ipfam:CorC_HlyC  
Legends: 1, TOPO_DOM Cytoplasmic (Potential); 2, TRANSMEM Potential; 3, TOPO_DOM Periplasmic (Potential); 4, ipfam:CBS [T].
ID   YFJD_ECOLI              Reviewed;         428 AA.
AC   P37908; P76600; P76601; P77009; Q6BF70;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 5.
DT   03-NOV-2009, entry version 80.
DE   RecName: Full=UPF0053 inner membrane protein yfjD;
GN   Name=yfjD; Synonyms=ypjE; OrderedLocusNames=b4461, JW5415;
GN   ORFNames=b2612/b2613;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   MEDLINE=97349980; PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA   Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K.,
RA   Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N.,
RA   Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H.,
RA   Oshima T., Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S.,
RA   Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C.,
RA   Yamagata S., Horiuchi T.;
RT   "Construction of a contiguous 874-kb sequence of the Escherichia coli-
RT   K12 genome corresponding to 50.0-68.8 min on the linkage map and
RT   analysis of its sequence features.";
RL   DNA Res. 4:91-113(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   MEDLINE=97426617; PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J.,
RA   Mau B., Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1474(1997).
RN   [3]
RP   SEQUENCE REVISION.
RX   PubMed=16397293; DOI=10.1093/nar/gkj405;
RA   Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R.,
RA   Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T.,
RA   Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H.,
RA   Thomas G.H., Thomson N.R., Wishart D., Wanner B.L.;
RT   "Escherichia coli K-12: a cooperatively developed annotation snapshot
RT   -- 2005.";
RL   Nucleic Acids Res. 34:1-9(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains
RT   MG1655 and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 322-428.
RC   STRAIN=B178;
RX   MEDLINE=88319942; PubMed=3045760; DOI=10.1093/nar/16.15.7545;
RA   Lipinska B., King J., Ang D., Georgopoulos C.;
RT   "Sequence analysis and transcriptional regulation of the Escherichia
RT   coli grpE gene, encoding a heat shock protein.";
RL   Nucleic Acids Res. 16:7545-7562(1988).
RN   [6]
RP   IDENTIFICATION.
RA   Rudd K.E.;
RL   Unpublished observations (AUG-1994).
RN   [7]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the UPF0053 family.
CC   -!- SIMILARITY: Contains 2 CBS domains.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=X07863; Type=Frameshift; Positions=326, 331, 348;
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DR   EMBL; U00096; AAT48144.3; -; Genomic_DNA.
DR   EMBL; AP009048; BAA16497.2; ALT_INIT; Genomic_DNA.
DR   EMBL; X07863; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; AP_003193.1; -.
DR   RefSeq; YP_026171.3; -.
DR   DIP; DIP:12070N; -.
DR   STRING; P37908; -.
DR   GeneID; 2847739; -.
DR   GenomeReviews; AP009048_GR; JW5415.
DR   GenomeReviews; U00096_GR; b4461.
DR   KEGG; ecj:JW5415; -.
DR   KEGG; eco:b4461; -.
DR   EchoBASE; EB2336; -.
DR   EcoGene; EG12442; yfjD.
DR   HOGENOM; P37908; -.
DR   OMA; IPDGDVC; -.
DR   BioCyc; EcoCyc:G7356-MON; -.
DR   Genevestigator; P37908; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR005170; CorC_transpt-asc.
DR   InterPro; IPR000644; Cysta_beta_synth_core.
DR   InterPro; IPR002550; DUF21.
DR   Pfam; PF00571; CBS; 1.
DR   Pfam; PF03471; CorC_HlyC; 1.
DR   Pfam; PF01595; DUF21; 1.
DR   PROSITE; PS51371; CBS; 1.
PE   1: Evidence at protein level;
KW   CBS domain; Cell inner membrane; Cell membrane; Complete proteome;
KW   Membrane; Repeat; Transmembrane.
FT   CHAIN         1    428       UPF0053 inner membrane protein yfjD.
FT                                /FTId=PRO_0000088357.
FT   TOPO_DOM      1      3       Cytoplasmic (Potential).
FT   TRANSMEM      4     24       Potential.
FT   TOPO_DOM     25     64       Periplasmic (Potential).
FT   TRANSMEM     65     85       Potential.
FT   TOPO_DOM     86     91       Cytoplasmic (Potential).
FT   TRANSMEM     92    112       Potential.
FT   TOPO_DOM    113    129       Periplasmic (Potential).
FT   TRANSMEM    130    150       Potential.
FT   TOPO_DOM    151    428       Cytoplasmic (Potential).
FT   DOMAIN      208    270       CBS 1.
FT   DOMAIN      272    332       CBS 2.
CC   --------------------------------------------------------------------------
CC   The following FT lines are automated annotations from the MyHits database.
CC   --------------------------------------------------------------------------
FT   MYHIT        11    184       ipfam:DUF21 [T]
FT   MYHIT       342    420       ismart:CorC_HlyC [T]
FT   MYHIT       278    326       ipfam:CBS [T]
FT   MYHIT       272    332       iprf:CBS [T]
FT   MYHIT       344    418       ipfam:CorC_HlyC [T]
SQ   SEQUENCE   428 AA;  48044 MW;  38456865EDBCB151 CRC64;
     MEHISTTTLI IILIIMVVIS AYFSGSETGM MTLNRYRLRH MAKQGNRSAK RVEKLLRKPD
     RLISLVLIGN NLVNILASAL GTIVGMRLYG DAGVAIATGV LTFVVLVFAE VLPKTIAALY
     PEKVAYPSSF LLAPLQILMM PLVWLLNAIT RMLMRMMGIK TDIVVSGSLS KEELRTIVHE
     SRSQISRRNQ DMLLSVLDLE KMTVDDIMVP RSEIIGIDIN DDWKSILRQL SHSPHGRIVL
     YRDSLDDAIS MLRVREAWRL MSEKKEFTKE TMLRAADEIY FVPEGTPLST QLVKFQRNKK
     KVGLVVNEYG DIQGLVTVED ILEEIVGDFT TSMSPTLAEE VTPQNDGSVI IDGTANVREI
     NKAFNWHLPE DDARTVNGVI LEALEEIPVA GTRVRIGEYD IDILDVQDNM IKQVKVFPVK
     PLRESVAE
//