ID YFJD_ECOLI Reviewed; 428 AA.
AC P37908; P76600; P76601; P77009; Q6BF70;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 5.
DT 03-NOV-2009, entry version 80.
DE RecName: Full=UPF0053 inner membrane protein yfjD;
GN Name=yfjD; Synonyms=ypjE; OrderedLocusNames=b4461, JW5415;
GN ORFNames=b2612/b2613;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX MEDLINE=97349980; PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K.,
RA Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N.,
RA Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H.,
RA Oshima T., Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S.,
RA Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C.,
RA Yamagata S., Horiuchi T.;
RT "Construction of a contiguous 874-kb sequence of the Escherichia coli-
RT K12 genome corresponding to 50.0-68.8 min on the linkage map and
RT analysis of its sequence features.";
RL DNA Res. 4:91-113(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX MEDLINE=97426617; PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J.,
RA Mau B., Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1474(1997).
RN [3]
RP SEQUENCE REVISION.
RX PubMed=16397293; DOI=10.1093/nar/gkj405;
RA Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R.,
RA Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T.,
RA Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H.,
RA Thomas G.H., Thomson N.R., Wishart D., Wanner B.L.;
RT "Escherichia coli K-12: a cooperatively developed annotation snapshot
RT -- 2005.";
RL Nucleic Acids Res. 34:1-9(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains
RT MG1655 and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 322-428.
RC STRAIN=B178;
RX MEDLINE=88319942; PubMed=3045760; DOI=10.1093/nar/16.15.7545;
RA Lipinska B., King J., Ang D., Georgopoulos C.;
RT "Sequence analysis and transcriptional regulation of the Escherichia
RT coli grpE gene, encoding a heat shock protein.";
RL Nucleic Acids Res. 16:7545-7562(1988).
RN [6]
RP IDENTIFICATION.
RA Rudd K.E.;
RL Unpublished observations (AUG-1994).
RN [7]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane
CC protein.
CC -!- SIMILARITY: Belongs to the UPF0053 family.
CC -!- SIMILARITY: Contains 2 CBS domains.
CC -!- SEQUENCE CAUTION:
CC Sequence=X07863; Type=Frameshift; Positions=326, 331, 348;
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DR EMBL; U00096; AAT48144.3; -; Genomic_DNA.
DR EMBL; AP009048; BAA16497.2; ALT_INIT; Genomic_DNA.
DR EMBL; X07863; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; AP_003193.1; -.
DR RefSeq; YP_026171.3; -.
DR DIP; DIP:12070N; -.
DR STRING; P37908; -.
DR GeneID; 2847739; -.
DR GenomeReviews; AP009048_GR; JW5415.
DR GenomeReviews; U00096_GR; b4461.
DR KEGG; ecj:JW5415; -.
DR KEGG; eco:b4461; -.
DR EchoBASE; EB2336; -.
DR EcoGene; EG12442; yfjD.
DR HOGENOM; P37908; -.
DR OMA; IPDGDVC; -.
DR BioCyc; EcoCyc:G7356-MON; -.
DR Genevestigator; P37908; -.
DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR005170; CorC_transpt-asc.
DR InterPro; IPR000644; Cysta_beta_synth_core.
DR InterPro; IPR002550; DUF21.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR Pfam; PF01595; DUF21; 1.
DR PROSITE; PS51371; CBS; 1.
PE 1: Evidence at protein level;
KW CBS domain; Cell inner membrane; Cell membrane; Complete proteome;
KW Membrane; Repeat; Transmembrane.
FT CHAIN 1 428 UPF0053 inner membrane protein yfjD.
FT /FTId=PRO_0000088357.
FT TOPO_DOM 1 3 Cytoplasmic (Potential).
FT TRANSMEM 4 24 Potential.
FT TOPO_DOM 25 64 Periplasmic (Potential).
FT TRANSMEM 65 85 Potential.
FT TOPO_DOM 86 91 Cytoplasmic (Potential).
FT TRANSMEM 92 112 Potential.
FT TOPO_DOM 113 129 Periplasmic (Potential).
FT TRANSMEM 130 150 Potential.
FT TOPO_DOM 151 428 Cytoplasmic (Potential).
FT DOMAIN 208 270 CBS 1.
FT DOMAIN 272 332 CBS 2.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 11 184 ipfam:DUF21 [T]
FT MYHIT 342 420 ismart:CorC_HlyC [T]
FT MYHIT 278 326 ipfam:CBS [T]
FT MYHIT 272 332 iprf:CBS [T]
FT MYHIT 344 418 ipfam:CorC_HlyC [T]
SQ SEQUENCE 428 AA; 48044 MW; 38456865EDBCB151 CRC64;
MEHISTTTLI IILIIMVVIS AYFSGSETGM MTLNRYRLRH MAKQGNRSAK RVEKLLRKPD
RLISLVLIGN NLVNILASAL GTIVGMRLYG DAGVAIATGV LTFVVLVFAE VLPKTIAALY
PEKVAYPSSF LLAPLQILMM PLVWLLNAIT RMLMRMMGIK TDIVVSGSLS KEELRTIVHE
SRSQISRRNQ DMLLSVLDLE KMTVDDIMVP RSEIIGIDIN DDWKSILRQL SHSPHGRIVL
YRDSLDDAIS MLRVREAWRL MSEKKEFTKE TMLRAADEIY FVPEGTPLST QLVKFQRNKK
KVGLVVNEYG DIQGLVTVED ILEEIVGDFT TSMSPTLAEE VTPQNDGSVI IDGTANVREI
NKAFNWHLPE DDARTVNGVI LEALEEIPVA GTRVRIGEYD IDILDVQDNM IKQVKVFPVK
PLRESVAE
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