ID UBIX_VIBCH Reviewed; 211 AA.
AC Q9KP38;
DT 21-FEB-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 15-MAR-2017, entry version 77.
DE RecName: Full=Flavin prenyltransferase UbiX {ECO:0000255|HAMAP-Rule:MF_01984};
DE EC=2.5.1.129 {ECO:0000255|HAMAP-Rule:MF_01984};
GN Name=ubiX {ECO:0000255|HAMAP-Rule:MF_01984};
GN OrderedLocusNames=VC_2541;
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC Vibrionaceae; Vibrio.
OX NCBI_TaxID=243277;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A.,
RA Gill S.R., Nelson K.E., Read T.D., Tettelin H., Richardson D.L.,
RA Ermolaeva M.D., Vamathevan J.J., Bass S., Qin H., Dragoi I.,
RA Sellers P., McDonald L.A., Utterback T.R., Fleischmann R.D.,
RA Nierman W.C., White O., Salzberg S.L., Smith H.O., Colwell R.R.,
RA Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
CC -!- FUNCTION: Flavin prenyltransferase that catalyzes the synthesis of
CC the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-
CC polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase
CC is metal-independent and links a dimethylallyl moiety from
CC dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms
CC of FMN. {ECO:0000255|HAMAP-Rule:MF_01984}.
CC -!- CATALYTIC ACTIVITY: Dimethylallyl phosphate + FMNH(2) = prenylated
CC FMNH(2) + phosphate. {ECO:0000255|HAMAP-Rule:MF_01984}.
CC -!- SIMILARITY: Belongs to the UbiX/PAD1 family. {ECO:0000255|HAMAP-
CC Rule:MF_01984}.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AE003852; AAF95682.1; -; Genomic_DNA.
DR PIR; G82063; G82063.
DR RefSeq; NP_232169.1; NC_002505.1.
DR RefSeq; WP_001883898.1; NC_002505.1.
DR ProteinModelPortal; Q9KP38; -.
DR SMR; Q9KP38; -.
DR STRING; 243277.VC2541; -.
DR DNASU; 2615558; -.
DR EnsemblBacteria; AAF95682; AAF95682; VC_2541.
DR GeneID; 2615558; -.
DR KEGG; vch:VC2541; -.
DR PATRIC; 20084105; VBIVibCho83274_2419.
DR eggNOG; ENOG4108UMA; Bacteria.
DR eggNOG; COG0163; LUCA.
DR KO; K03186; -.
DR OMA; QGLVPRW; -.
DR BioCyc; VCHO:VC2541-MONOMER; -.
DR Proteomes; UP000000584; Chromosome 1.
DR GO; GO:0008694; F:3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity; ISS:TIGR.
DR GO; GO:0016831; F:carboxy-lyase activity; IBA:GO_Central.
DR GO; GO:0004659; F:prenyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009108; P:coenzyme biosynthetic process; IBA:GO_Central.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; ISS:TIGR.
DR Gene3D; 3.40.50.1950; -; 1.
DR HAMAP; MF_01984; ubiX_pad; 1.
DR InterPro; IPR003382; Flavoprotein.
DR InterPro; IPR004507; UbiX_Pad1.
DR PANTHER; PTHR43374; PTHR43374; 1.
DR Pfam; PF02441; Flavoprotein; 1.
DR SUPFAM; SSF52507; SSF52507; 1.
DR TIGRFAMs; TIGR00421; ubiX_pad; 1.
PE 3: Inferred from homology;
KW Complete proteome; Flavoprotein; FMN; Prenyltransferase;
KW Reference proteome; Transferase.
FT CHAIN 1 211 Flavin prenyltransferase UbiX.
FT /FTId=PRO_0000134975.
FT NP_BIND 15 17 FMN. {ECO:0000255|HAMAP-Rule:MF_01984}.
FT NP_BIND 106 109 FMN. {ECO:0000255|HAMAP-Rule:MF_01984}.
FT BINDING 41 41 FMN. {ECO:0000255|HAMAP-Rule:MF_01984}.
FT BINDING 141 141 FMN. {ECO:0000255|HAMAP-Rule:MF_01984}.
FT BINDING 171 171 DMAP. {ECO:0000255|HAMAP-Rule:MF_01984}.
FT BINDING 187 187 DMAP. {ECO:0000255|HAMAP-Rule:MF_01984}.
CC --------------------------------------------------------------------------
CC The following FT lines are automated annotations from the MyHits database.
CC --------------------------------------------------------------------------
FT MYHIT 7 204 ihamap:ubiX_pad [T]
FT MYHIT 8 183 ipfam:Flavoprotein [T]
SQ SEQUENCE 211 AA; 22731 MW; 11D78C878DEB1F22 CRC64;
MSMNNNRTIT LAWTGASGAP YGLRLLQCLL AADYQVYLLI SSAARVVLAT EHGLKLPANP
EAAQAALVEH LGCASDKLVV CGKEDWFSPV ASGSAAPKQM VVCPCSAGSV AAIAHGMSDN
LIERAADVVL KERGQLLLVV RETPFSTLHL ENMLKLSHMG VTIMPAAPGF YHQPQSIDDL
VDFMVARILD HLGIEQALVP RWGYDQRVRG E
//
|
