Entry euk:Q68EK3_DANRE

ID   Q68EK3_DANRE            Unreviewed;       385 AA.
AC   Q68EK3;
DT   11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   11-OCT-2004, sequence version 1.
DT   10-MAY-2017, entry version 89.
DE   SubName: Full=Transmembrane protein 144a {ECO:0000313|Ensembl:ENSDARP00000054439};
DE   SubName: Full=Zgc:100814 {ECO:0000313|EMBL:AAH80225.1};
GN   Name=tmem144a {ECO:0000313|Ensembl:ENSDARP00000054439,
GN   ECO:0000313|ZFIN:ZDB-GENE-040822-12};
GN   ORFNames=zgc:100814 {ECO:0000313|EMBL:AAH80225.1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH80225.1};
RN   [1] {ECO:0000313|EMBL:AAH80225.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Singapore local strain {ECO:0000313|EMBL:AAH80225.1};
RC   TISSUE=Embryo {ECO:0000313|EMBL:AAH80225.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AAI52622.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary {ECO:0000313|EMBL:AAI52622.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSDARP00000054439}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000054439};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [4] {ECO:0000313|Ensembl:ENSDARP00000054439, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000054439,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
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DR   EMBL; CR762427; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC080225; AAH80225.1; -; mRNA.
DR   EMBL; BC152621; AAI52622.1; -; mRNA.
DR   RefSeq; NP_001003999.1; NM_001003999.1.
DR   UniGene; Dr.29999; -.
DR   Ensembl; ENSDART00000054440; ENSDARP00000054439; ENSDARG00000037409.
DR   GeneID; 445495; -.
DR   KEGG; dre:445495; -.
DR   CTD; 445495; -.
DR   ZFIN; ZDB-GENE-040822-12; tmem144a.
DR   eggNOG; ENOG410IHKE; Eukaryota.
DR   eggNOG; ENOG410XRUY; LUCA.
DR   GeneTree; ENSGT00390000012574; -.
DR   HOGENOM; HOG000019514; -.
DR   HOVERGEN; HBG108575; -.
DR   OMA; FFVANQH; -.
DR   OrthoDB; EOG091G0D8X; -.
DR   TreeFam; TF313673; -.
DR   Proteomes; UP000000437; Chromosome 1.
DR   Bgee; ENSDARG00000037409; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010651; Sugar_transport.
DR   InterPro; IPR012435; TMEM144.
DR   PANTHER; PTHR16119; PTHR16119; 1.
DR   Pfam; PF07857; TMEM144; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    385       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5010141397.
FT   TRANSMEM     45     65       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     77     96       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    102    124       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    131    152       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    164    183       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    231    251       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    271    293       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    305    325       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    331    354       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    363    382       Helical. {ECO:0000256|SAM:Phobius}.
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CC   The following FT lines are automated annotations from the MyHits database.
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FT   MYHIT        48    384       ipfam:TMEM144 [T]
SQ   SEQUENCE   385 AA;  41890 MW;  D17FDE28B1B9FE25 CRC64;
     MNPYVTAFIV ALICALSTGA AQHLEKENWL SHRPIESNST SNSSDLTYGF ISCAVSAVFF
     GSNFVPVKKI ETGDGMFFQW ILCAAIWTVS LVVNIILNSP KFWPLVMLGG AIWATGNITV
     VPIVKTIGLG LGLLIWASFN LLLGWASSRF GWFGIGAETV SKPVLNYCGA GVCLFSAIVF
     FFVKTDVQRS TTSEETPLLI DHVVNAESVV ATDDSWVDAL SPRMKRFVGS FLAVVAGLLY
     GSSFVPVLYI KNHASDPDSP YNGASQFDLD YVFAQYSGIF LASTVYFLLY CAIKRNKPQV
     FPKAVLPGFL SGIMWGVATC CWFLANHYLS AVVSFPIITT VPGLIAALWG VLVFKEVKGC
     RNYIVLIFAF CLVLSGALMT AFSKI
//